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pSTTa-GPA1-Q222L

Plasmid

#248650

Purpose

Vector for protein expression of 2x StrepII-tagged Arabidopsis heterotrimeric G protein GPA1-Q222L ("constitutively active" mutant) in E. coli.

Depositor

Sarah Assmann

Publication

Gookin et al Front Mol Biosci. 2025 Apr 7;12:1513660.

Insert

GPA1 (GP ALPHA 1 Mustard Weed)

Tags

2x StrepII, Thrombin site, TEV site

Expression

Bacterial

Mutation

Q222L

Promoter

tac

Available since

Jan. 13, 2026

Availability

Academic Institutions and Nonprofits only

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pCAG coca-GlyR-IRES-GFP

Plasmid

#242194

Purpose

Expression vector for cocaine-gated chemogenetic anion channel

Depositor

Scott Sternson

Publication

Gomez et al Nature. 2025 Aug 27. doi: 10.1038/s41586

Insert

coca-GlyR-IRES-GFP

Expression

Mammalian

Mutation

L141G G175K Y217F

Promoter

CAG

Available since

Dec. 15, 2025

Availability

Academic Institutions and Nonprofits only

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pCAG coca-5HT3-IRES-GFP

Plasmid

#242193

Purpose

Expression vector for cocaine-gated chemogenetic cation channel

Depositor

Scott Sternson

Publication

Gomez et al Nature. 2025 Aug 27. doi: 10.1038/s41586

Insert

coca-5HT3-IRES-GFP (Htr3a Mouse)

Expression

Mammalian

Mutation

L141G G175K Y210F Y217F

Promoter

CAG

Available since

Oct. 2, 2025

Availability

Academic Institutions and Nonprofits only

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NPM1c-TurboID-MSCV-IRES-GFP

Plasmid

#240129

Purpose

Expresses mutant NPM1c-TurboID fusion in mammalian cells

Depositor

Timothy Ley

Publication

Kramer et al J Clin Invest. 2025 Aug 7:e195929. doi:

Insert

NPM1c (NPM1 Human)

Use

Retroviral

Tags

IRES-GFP and TurboID

Expression

Mammalian

Mutation

C-terminal frameshift mutation as seen in Acute M…

Available since

Aug. 7, 2025

Availability

Academic Institutions and Nonprofits only

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Gab2-TurboID-MSCV-IRES-GFP

Plasmid

#240131

Purpose

Expresses Gab2-TurboID fusion in mammalian cells

Depositor

Timothy Ley

Publication

Kramer et al J Clin Invest. 2025 Aug 7:e195929. doi:

Insert

Gab2 (Gab2 Mouse)

Use

Retroviral

Tags

IRES-GFP and TurboID

Expression

Mammalian

Available since

Aug. 7, 2025

Availability

Academic Institutions and Nonprofits only

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TurboID-Gab2-MSCV-IRES-GFP

Plasmid

#240132

Purpose

Expresses TurboID-Gab2 fusion in mammalian cells

Depositor

Timothy Ley

Publication

Kramer et al J Clin Invest. 2025 Aug 7:e195929. doi:

Insert

Gab2 (Gab2 Mouse)

Use

Retroviral

Tags

IRES-GFP and TurboID

Expression

Mammalian

Available since

Aug. 7, 2025

Availability

Academic Institutions and Nonprofits only

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NPM1-TurboID-MSCV-IRES-GFP

Plasmid

#240134

Purpose

Expresses NPM1-TurboID fusion in mammalian cells

Depositor

Timothy Ley

Publication

Kramer et al J Clin Invest. 2025 Aug 7:e195929. doi:

Insert

NPM1 (NPM1 Human)

Use

Retroviral

Tags

IRES-GFP and TurboID

Expression

Mammalian

Available since

Aug. 7, 2025

Availability

Academic Institutions and Nonprofits only

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Gab2-MSCV-IRES-GFP

Plasmid

#240126

Purpose

Expresses Gab2 (mouse) in mammalian cells

Depositor

Timothy Ley

Publication

Kramer et al J Clin Invest. 2025 Aug 7:e195929. doi:

Insert

Gab2 (Gab2 Mouse)

Use

Retroviral

Tags

IRES-GFP

Expression

Mammalian

Available since

Aug. 7, 2025

Availability

Academic Institutions and Nonprofits only

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Pak1-MSCV-IRES-GFP

Plasmid

#240127

Purpose

Expresses Pak1 (mouse) in mammalian cells

Depositor

Timothy Ley

Publication

Kramer et al J Clin Invest. 2025 Aug 7:e195929. doi:

Insert

Pak1 (Pak1 Mouse)

Use

Retroviral

Tags

IRES-GFP

Expression

Mammalian

Available since

Aug. 7, 2025

Availability

Academic Institutions and Nonprofits only

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proUBI10::VIH2-FL::FLAG-H505A-H741A-H975A

Plasmid

#238337

Purpose

proUBI10::VIH2-FL::FLAG-H505A-H741A-H975A ubiquitous expression in Arabidopsis plants

Depositor

Michael Hothorn

Publication

Raia et al Nat Commun. 2025 Feb 19;16(1):1753. doi:

Insert

VIP1 (VIP1 Mustard Weed)

Tags

3x Flag-tag

Expression

Plant

Mutation

AtVIH2-H505A-H741A-H975A

Available since

Aug. 4, 2025

Availability

Academic Institutions and Nonprofits only

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pFastBac1-ScVip1-536-1107-delta848-918-R547A-H548A-R551A

Plasmid

#238314

Purpose

ScVip1-536-1107-delta848-918-R547A-H548A-R551A protein expression in insect cells

Depositor

Michael Hothorn

Publication

Raia et al Nat Commun. 2025 Feb 19;16(1):1753. doi:

Insert

VIP1 (VIP1 Budding Yeast)

Tags

His10-Tag, Twin-Strep-tag, TEV

Expression

Insect

Mutation

ScVip1-536-1107-delta848-918-R547A-H548A-R551A

Available since

July 14, 2025

Availability

Academic Institutions and Nonprofits only

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pBB3-ScVip1-536-1107-R547A-H548A-R551A

Plasmid

#238317

Purpose

ScVip1-536-1107-R547A-H548A-R551A protein expression in insect cells

Depositor

Michael Hothorn

Publication

Raia et al Nat Commun. 2025 Feb 19;16(1):1753. doi:

Insert

VIP1 (VIP1 Budding Yeast)

Tags

His10-Tag, Twin-Strep-tag, TEV

Expression

Insect

Mutation

ScVip1-536-1107-R547A-H548A-R551A

Available since

July 14, 2025

Availability

Academic Institutions and Nonprofits only

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pBB3-ScVip1-536-1107-E576A-K623A-Q625S-K627A

Plasmid

#238327

Purpose

ScVip1-536-1107-E576A-K623A-Q625S-K627A protein expression in insect cells

Depositor

Michael Hothorn

Publication

Raia et al Nat Commun. 2025 Feb 19;16(1):1753. doi:

Insert

VIP1 (VIP1 Budding Yeast)

Tags

His10-Tag, Twin-Strep-tag, TEV

Expression

Insect

Mutation

ScVip1-536-1107-E576A-K623A-Q625S-K627A

Available since

July 14, 2025

Availability

Academic Institutions and Nonprofits only

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pKLV2-U6gRNA5(hEGFR_2b)-PGKpuro2ABFP-W

Plasmid

#208432

Purpose

Lentiviral gRNA plasmid targeting human EGFR gene, co-expression of BFP tag

Depositor

Sok Ching Cheong

Publication

Chai et al Heliyon. 2024 Oct 22;10(21):e39677. doi:

Insert

EGFR (EGFR Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Mutation

N/A

Promoter

human U6

Available since

July 1, 2025

Availability

Academic Institutions and Nonprofits only

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pKLV2-U6gRNA5(hPTPN11_1k)-PGKpuro2ABFP-W

Plasmid

#208427

Purpose

Lentiviral gRNA plasmid targeting human PTPN11 gene, co-expression of BFP tag

Depositor

Sok Ching Cheong

Publication

Chai et al Heliyon. 2024 Oct 22;10(21):e39677. doi:

Insert

PTPN11 (PTPN11 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Mutation

N/A

Promoter

human U6

Available since

July 1, 2025

Availability

Academic Institutions and Nonprofits only

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pKLV2-U6gRNA5(hPTPN11_2b)-PGKpuro2ABFP-W

Plasmid

#208428

Purpose

Lentiviral gRNA plasmid targeting human PTPN11 gene, co-expression of BFP tag

Depositor

Sok Ching Cheong

Publication

Chai et al Heliyon. 2024 Oct 22;10(21):e39677. doi:

Insert

PTPN11 (PTPN11 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Mutation

N/A

Promoter

human U6

Available since

July 1, 2025

Availability

Academic Institutions and Nonprofits only

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pKLV2-U6gRNA5(hMTOR_1k)-PGKpuro2ABFP-W

Plasmid

#208429

Purpose

Lentiviral gRNA plasmid targeting human MTOR gene, co-expression of BFP tag

Depositor

Sok Ching Cheong

Publication

Chai et al Heliyon. 2024 Oct 22;10(21):e39677. doi:

Insert

MTOR (MTOR Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Mutation

N/A

Promoter

human U6

Available since

July 1, 2025

Availability

Academic Institutions and Nonprofits only

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pKLV2-U6gRNA5(hMTOR_2b)-PGKpuro2ABFP-W

Plasmid

#208430

Purpose

Lentiviral gRNA plasmid targeting human MTOR gene, co-expression of BFP tag

Depositor

Sok Ching Cheong

Publication

Chai et al Heliyon. 2024 Oct 22;10(21):e39677. doi:

Insert

MTOR (MTOR Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Mutation

N/A

Promoter

human U6

Available since

July 1, 2025

Availability

Academic Institutions and Nonprofits only

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pKLV2-U6gRNA5(hEGFR_1k)-PGKpuro2ABFP-W

Plasmid

#208431

Purpose

Lentiviral gRNA plasmid targeting human EGFR gene, co-expression of BFP tag

Depositor

Sok Ching Cheong

Publication

Chai et al Heliyon. 2024 Oct 22;10(21):e39677. doi:

Insert

EGFR (EGFR Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Mutation

N/A

Promoter

human U6

Available since

July 1, 2025

Availability

Academic Institutions and Nonprofits only

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pBB3-ScVip1-536-1107-K554A-K556A-K644A

Plasmid

#238328

Purpose

ScVip1-536-1107-K554A-K556A-K644A protein expression in insect cells

Depositor

Michael Hothorn

Publication

Raia et al Nat Commun. 2025 Feb 19;16(1):1753. doi:

Insert

VIP1 (VIP1 Budding Yeast)

Tags

His10-Tag, Twin-Strep-tag, TEV

Expression

Insect

Mutation

ScVip1-536-1107-K554A-K556A-K644A

Available since

June 12, 2025

Availability

Academic Institutions and Nonprofits only

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