Purpose
Expresses EFS promoter driven human codon optimized SpdCas9 directly fused to Dnmt3A/3L variant catΔ (C706A and R832E) followed by P2A-mCherry
Insert
S. pyogenes dCas9 with C-terminal fusion of murine Dnmt3A-Dnmt3L variant catΔ (C706A and R832E) engineered fusion
Mutation
D10A and H840A in S.pyogenes Cas9; C706A and R832…
Available since
Feb. 7, 2025
Availability
Academic Institutions and Nonprofits only