We narrowed to 11,278 results for: Vars;

1. pBiT3.1-N_GEMIN5:1-1508

   Plasmid

   #211123

   Purpose

   Mammalian expression of full-length human GEMIN5. N-terminal HiBiT tag.

   Depositor

   Cheryl Arrowsmith

   Article

   Ackloo et al J Med Chem. 2025 Jan 23;68(2):1092-1112.

   Insert

   Gemin5:M1-M1508 (GEMIN5 Human)
   

   Tags

   MVSGWRLFKKISGSSGGSSG

   Expression

   Mammalian

   Mutation

   R682Q natural variant (VAR_033807)

   Promoter

   CMV

   Available Since

   March 19, 2024

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

2. pBiT3.1-N_EML1:1-815

   Plasmid

   #211240

   Purpose

   Mammalian expression of full-length human EML1. N-terminal HiBiT tag.

   Depositor

   Cheryl Arrowsmith

   Article

   Ackloo et al J Med Chem. 2025 Jan 23;68(2):1092-1112.

   Insert

   EML1:M1-I815 (EML1 Human)
   

   Tags

   MVSGWRLFKKISGSSGGSSG

   Expression

   Mammalian

   Mutation

   H552N natural variant (VAR_031721)

   Promoter

   CMV

   Available Since

   March 19, 2024

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

3. pBiT3.1-N_EML4:1-981

   Plasmid

   #211241

   Purpose

   Mammalian expression of full-length human EML4. N-terminal HiBiT tag.

   Depositor

   Cheryl Arrowsmith

   Article

   Ackloo et al J Med Chem. 2025 Jan 23;68(2):1092-1112.

   Insert

   EML4:M1-S981 (EML4 Human)
   

   Tags

   MVSGWRLFKKISGSSGGSSG

   Expression

   Mammalian

   Mutation

   I382V natural variant (VAR_031727)

   Promoter

   CMV

   Available Since

   March 19, 2024

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

4. pBiT3.1-N_DCAF12:1-453

   Plasmid

   #211198

   Purpose

   Mammalian expression of full-length human DCAF12 N-terminal HiBiT tag.

   Depositor

   Cheryl Arrowsmith

   Article

   Ackloo et al J Med Chem. 2025 Jan 23;68(2):1092-1112.

   Insert

   DCAF12:M1-S453 (DCAF12 Human)
   

   Tags

   MVSGWRLFKKISGSSGGSSG

   Expression

   Mammalian

   Mutation

   R131Q natural variant (VAR_035322)

   Promoter

   CMV

   Available Since

   March 19, 2024

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

5. pBiT3.1-C_GEMIN5:1-739

   Plasmid

   #211165

   Purpose

   Mammalian expression of human GEMIN5 fragment M1 to A739. C-terminal HiBiT tag.

   Depositor

   Cheryl Arrowsmith

   Article

   Ackloo et al J Med Chem. 2025 Jan 23;68(2):1092-1112.

   Insert

   Gemin5:M1-A739 (GEMIN5 Human)
   

   Tags

   GSSGGSSGVSGWRLFKKIS

   Expression

   Mammalian

   Mutation

   R682Q natural variant (VAR_033807)

   Promoter

   CMV

   Available Since

   March 19, 2024

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

6. pBiT3.1-C_LRRK2:2142-2527

   Plasmid

   #211151

   Purpose

   Mammalian expression of human LRRK2 fragment R2142 to E2527. C-terminal HiBiT tag.

   Depositor

   Cheryl Arrowsmith

   Article

   Ackloo et al J Med Chem. 2025 Jan 23;68(2):1092-1112.

   Insert

   LRRK2:R2142-E2527 (LRRK2 Human)
   

   Tags

   GSSGGSSGVSGWRLFKKIS

   Expression

   Mammalian

   Mutation

   M2397T natural variant ( VAR_024965)

   Promoter

   CMV

   Available Since

   March 19, 2024

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

7. pBiT3.1-C_EML1:1-815

   Plasmid

   #211314

   Purpose

   Mammalian expression of full-length human EML1. C-terminal HiBiT tag.

   Depositor

   Cheryl Arrowsmith

   Article

   Ackloo et al J Med Chem. 2025 Jan 23;68(2):1092-1112.

   Insert

   EML1:M1-I815 (EML1 Human)
   

   Tags

   GSSGGSSGVSGWRLFKKIS

   Expression

   Mammalian

   Mutation

   H552N natural variant (VAR_031721)

   Promoter

   CMV

   Available Since

   Feb. 21, 2024

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

8. pBiT3.1-C_ATG16L1:1-607

   Plasmid

   #211308

   Purpose

   Mammalian expression of full-length human ATG16L1. C-terminal HiBiT tag.

   Depositor

   Cheryl Arrowsmith

   Article

   Ackloo et al J Med Chem. 2025 Jan 23;68(2):1092-1112.

   Insert

   ATG16L1:M1-Y607 (ATG16L1 Human)
   

   Tags

   GSSGGSSGVSGWRLFKKIS

   Expression

   Mammalian

   Mutation

   T300A natural variant (VAR_021834)

   Promoter

   CMV

   Available Since

   Feb. 21, 2024

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

9. pBiT3.1-C_DCAF12:1-453

   Plasmid

   #211272

   Purpose

   Mammalian expression of full-length human DCAF12. C-terminal HiBiT tag.

   Depositor

   Cheryl Arrowsmith

   Article

   Ackloo et al J Med Chem. 2025 Jan 23;68(2):1092-1112.

   Insert

   DCAF12:M1-S453 (DCAF12 Human)
   

   Tags

   GSSGGSSGVSGWRLFKKIS

   Expression

   Mammalian

   Mutation

   R131Q natural variant (VAR_035322)

   Promoter

   CMV

   Available Since

   Feb. 21, 2024

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

10. pHTC-HaloTag_DCAF12:1-453

    Plasmid

    #210967

    Purpose

    Mammalian expression of full-length human DCAF12. C-terminal HaloTag.

    Depositor

    Cheryl Arrowsmith

    Article

    Ackloo et al J Med Chem. 2025 Jan 23;68(2):1092-1112.

    Insert

    DCAF12:M1-S453 (DCAF12 Human)
    

    Tags

    HaloTag

    Expression

    Mammalian

    Mutation

    R131Q natural variant (VAR_035322)

    Promoter

    CMV

    Available Since

    Feb. 21, 2024

    Availability

    Industry, Academic Institutions, and Nonprofits

    

    Enlarge

11. FGFR2 K41E 3xFlag

    Plasmid

    #110105

    Purpose

    expresses FGFR2 with a single amino acid change in mammalian cells

    Depositor

    Martin Fernandez-Zapico

    Article

    Egan et al JCO Precis Oncol. 2017;2017:PO.17.00018.

    Insert

    fibroblast growth factor receptor 2 (FGFR2 Human)
    

    Tags

    Flag

    Expression

    Mammalian

    Mutation

    mutated Lysine 41 to Glutamic acid (K41E)

    Promoter

    CMV

    Available Since

    May 3, 2018

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

12. pFBOH-avi-TEV-LIC_DCAF12:1-453

    Plasmid

    #210940

    Purpose

    Insect expression of full-length human DCAF12. N-terminal 6X His tag, biotin acceptor peptide tag and TEV cleavage site.

    Depositor

    Cheryl Arrowsmith

    Article

    Ackloo et al J Med Chem. 2025 Jan 23;68(2):1092-1112.

    Insert

    DCAF12:M1-S453 (DCAF12 Human)
    

    Expression

    Insect

    Mutation

    R131Q natural variant (VAR_035322)

    Promoter

    Polyhedrin

    Available Since

    March 20, 2024

    Availability

    Industry, Academic Institutions, and Nonprofits

    

    Enlarge

13. pFBD-BirA_LRRK2:2141-2527

    Plasmid

    #210901

    Purpose

    Insect expression of human LRRK2 fragment T2141 to E2527. N-terminal biotin acceptor peptide tag and C-terminal 6X His tag.

    Depositor

    Cheryl Arrowsmith

    Article

    Ackloo et al J Med Chem. 2025 Jan 23;68(2):1092-1112.

    Insert

    LRRK2:T2141-E2527 (LRRK2 Human)
    

    Tags

    GGSGHHHHHH and MSGLNDIFEAQKIEWHEGSAGGSG

    Expression

    Insect

    Mutation

    M2397T natural variant ( VAR_024965)

    Promoter

    Polyhedrin

    Available Since

    March 1, 2024

    Availability

    Industry, Academic Institutions, and Nonprofits

    

    Enlarge

14. pBacMam2-DiEx-LIC_LRRK2:2141-2527

    Plasmid

    #210900

    Purpose

    Insect expression of human LRRK2 fragment T2141 to E2527. C-terminal 10X His and Flag tag with TEV cleavage site.

    Depositor

    Cheryl Arrowsmith

    Article

    Ackloo et al J Med Chem. 2025 Jan 23;68(2):1092-1112.

    Insert

    LRRK2:T2141-E2527 (LRRK2 Human)
    

    Tags

    AENLYFQSHHHHHHHHHHDYKDDDDK and M

    Expression

    Insect

    Mutation

    M2397T natural variant ( VAR_024965)

    Promoter

    P10 and CMV

    Available Since

    March 1, 2024

    Availability

    Industry, Academic Institutions, and Nonprofits

    

    Enlarge

15. AiP13450: pAAV-AiE0140h-minBG-iCre-4X2C-WPRE3-BGHpA (Alias: CN3450)

    Plasmid

    #214845

    Purpose

    Expression of iCre in striatal Pvalb neurons

    Depositor

    Jonathan Ting, Allen Institute for Brain Science

    Article

    Hunker et al Neuron. 2025 May 21;113(10):1507-1524.e1

    Insert

    iCre
    

    Use

    AAV

    Available Since

    July 15, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

16. pLVX-EF1alpha-eGFP-2xStrep-IRES-Puro

    Plasmid

    #141395

    Purpose

    Lentiviral expression of SARS-CoV-2 protein; transient expression and generate lentivirus

    Depositor

    Nevan Krogan

    Article

    Gordon et al Nature. 2020 Jul;583(7816):459-468. doi:

    Insert

    eGFP
    

    Use

    Lentiviral

    Tags

    2xStrep

    Expression

    Mammalian

    Mutation

    human codon optimized

    Promoter

    EF1alpha

    Available Since

    April 13, 2020

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

17. AiP13777: pAAV-AiE0682h-minBG-iCre(R297T)-BGHpA (Alias: CN3777)

    Plasmid

    #214847

    Purpose

    Expression of iCre(R297T) in striatal Sst neurons

    Depositor

    Jonathan Ting, Allen Institute for Brain Science

    Article

    Hunker et al Neuron. 2025 May 21;113(10):1507-1524.e1

    Insert

    iCre(R297T)
    

    Use

    AAV

    Mutation

    R297T

    Available Since

    July 15, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

18. AiP13780: pAAV-AiE0743m_3xC2-minBG-iCre(R297T)-BGHpA (Alias: CN3780)

    Plasmid

    #214848

    Purpose

    Expression of iCre(R297T) in striatal cholinergic neurons

    Depositor

    Jonathan Ting, Allen Institute for Brain Science

    Article

    Hunker et al Neuron. 2025 May 21;113(10):1507-1524.e1

    Insert

    iCre(R297T)
    

    Use

    AAV

    Mutation

    R297T

    Available Since

    July 15, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

19. AiP15646: pAAV-AiE1426m_3xC2-minBG-SYFP2-WPRE3-BGHpA (Alias: CN5646)

    Plasmid

    #230884

    Purpose

    AiE1426m_3xC2 is an enhancer sequence, designed to drive AAV-mediated transgene expression in cortical and striatal Sst-Chodl neurons

    Depositor

    Jonathan Ting, Allen Institute for Brain Science

    Article

    Hunker et al Neuron. 2025 May 21;113(10):1507-1524.e1

    Insert

    SYFP2
    

    Use

    AAV

    Expression

    Mammalian

    Available Since

    Jan. 29, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

20. AiP15138: pAAV-AiE0873m_3xC2-minBG-iCre(R297T)-BGHpA (Alias: CN5138)

    Plasmid

    #214868

    Purpose

    Expression of iCre(R297T) in striatal cholinergic neurons

    Depositor

    Jonathan Ting, Allen Institute for Brain Science

    Article

    Hunker et al Neuron. 2025 May 21;113(10):1507-1524.e1

    Insert

    iCre(R297T)
    

    Use

    AAV

    Mutation

    R297T

    Available Since

    July 15, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

21. AiP14573: pAAV-AiE0452h-minBG-FlpO-WPRE3-BGHpA (Alias: CN4573)

    Plasmid

    #230871

    Purpose

    AiE0452h is an enhancer sequence, designed to drive AAV-mediated transgene expression in striatal indirect pathway MSNs (D2-MSNs)

    Depositor

    Jonathan Ting, Allen Institute for Brain Science

    Article

    Hunker et al Neuron. 2025 May 21;113(10):1507-1524.e1

    Insert

    FlpO
    

    Use

    AAV

    Expression

    Mammalian

    Available Since

    Jan. 29, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

22. AiP14201: pAAV-AiE0779m_3xC2-minBG-FlpO-WPRE3-BGHpA (Alias: CN4201)

    Plasmid

    #214855

    Purpose

    Expression of FlpO in striatal direct pathway medium spiny neurons (D1 MSNs)

    Depositor

    Jonathan Ting, Allen Institute for Brain Science

    Article

    Hunker et al Neuron. 2025 May 21;113(10):1507-1524.e1

    Insert

    FlpO
    

    Use

    AAV

    Available Since

    July 15, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

23. AiP14460: pAAV-AiE0452h_3xC2-minBG-SYFP2-WPRE3-BarcodeR-BGHpA (Alias: CN4460)

    Plasmid

    #236599

    Purpose

    Barcoded enhancer AAV vector for multiplexed screening applications; AiE0452h_3xC2 is an enhancer active in striatal D2-MSNs and cortical L5_ET neurons

    Depositor

    Jonathan Ting

    Article

    Hunker et al Neuron. 2025 May 21;113(10):1507-1524.e1

    Insert

    SYFP2
    

    Use

    AAV

    Available Since

    May 14, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

24. AiP15745: pAAV-AiE0452h-minBG-mScarlet-WPRE3-BGHpA (Alias: CN5745)

    Plasmid

    #230880

    Purpose

    AiE0452h is an enhancer sequence, designed to drive AAV-mediated transgene expression in striatal indirect pathway MSNs (D2-MSNs)

    Depositor

    Jonathan Ting, Allen Institute for Brain Science

    Article

    Hunker et al Neuron. 2025 May 21;113(10):1507-1524.e1

    Insert

    mScarlet
    

    Use

    AAV

    Expression

    Mammalian

    Available Since

    Jan. 27, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

25. AiP12701: pAAV-hChATp-SYFP2-WPRE3-BGHpA (Alias: CN2701)

    Plasmid

    #236601

    Purpose

    hChATp is a promoter fragment with activity in striatal cholinergic neurons

    Depositor

    Jonathan Ting

    Article

    Hunker et al Neuron. 2025 May 21;113(10):1507-1524.e1

    Insert

    SYFP2
    

    Use

    AAV

    Available Since

    May 14, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

26. AiP12747 - pAAV-AiE0784m-minBG-SYFP2-WPRE3-BGHpA (Alias: CN2747)

    Plasmid

    #191710

    Purpose

    AI plasmid ALIAS: AiP12747. Expression of SYFP2 (yellow fluorescent protein) in striatal medium spiny neurons

    Depositor

    Jonathan Ting, Allen Institute for Brain Science

    Article

    Hunker et al Neuron. 2025 May 21;113(10):1507-1524.e1

    Insert

    SYFP2
    

    Use

    AAV

    Mutation

    none

    Available Since

    Feb. 1, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

27. AiP15827 - pAAV-AiE0780m-minCMV-SYFP2-WPRE3-BGHpA (Alias: CN5827)

    Plasmid

    #224206

    Purpose

    AiE0780m is an enhancer sequence, designed to drive AAV-mediated transgene expression in striatal D1 MSNs

    Depositor

    Jonathan Ting, Allen Institute for Brain Science

    Article

    Hunker et al Neuron. 2025 May 21;113(10):1507-1524.e1

    Insert

    SYFP2
    

    Use

    AAV

    Available Since

    Sept. 26, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

28. AiP12410 - pAAV-AiE0603m-minBG-SYFP2-WPRE3-BGHpA (Alias: CN2410)

    Plasmid

    #191738

    Purpose

    AI plasmid ALIAS: AiP12410. Expression of SYFP2 (yellow fluorescent protein) in striatal medium spiny neurons

    Depositor

    Jonathan Ting, Allen Institute for Brain Science

    Article

    Hunker et al Neuron. 2025 May 21;113(10):1507-1524.e1

    Insert

    SYFP2
    

    Use

    AAV

    Mutation

    none

    Available Since

    Feb. 1, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

29. AiP15385: pAAV-AiE0873m_3xC2-minBG-mScarlet-WPRE3-BGHpA (Alias: CN5385)

    Plasmid

    #230875

    Purpose

    AiE0873m_3xC2 is an enhancer sequence, designed to drive AAV-mediated transgene expression in striatal cholinergic interneurons

    Depositor

    Jonathan Ting, Allen Institute for Brain Science

    Article

    Hunker et al Neuron. 2025 May 21;113(10):1507-1524.e1

    Insert

    mScarlet
    

    Use

    AAV

    Expression

    Mammalian

    Available Since

    Jan. 29, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

30. AiP15747: pAAV-AiE0779m_3xC2-minBG-mScarlet-WPRE3-BGHpA (Alias: CN5747)

    Plasmid

    #230882

    Purpose

    AiE0779m_3xC2 is an enhancer sequence, designed to drive AAV-mediated transgene expression in striatal direct pathway MSNs (D1-MSNs)

    Depositor

    Jonathan Ting, Allen Institute for Brain Science

    Article

    Hunker et al Neuron. 2025 May 21;113(10):1507-1524.e1

    Insert

    mScarlet
    

    Use

    AAV

    Expression

    Mammalian

    Available Since

    Jan. 27, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge