We narrowed to 11,278 results for: Vars;

1. pHRSV_CHARMS-V43D/E52K/R62E

   Plasmid

   #233940

   Purpose

   Mammalian expression of Chimeric Higher-Order Assemblies for Receptor Mediated Signaling (CHARMS) variant: CHARMS three mutations in the death domain that disrupt oligomer formation

   Depositor

   Marcus Taylor

   Article

   Lichtenstein et al bioRxiv 2024.05.08.593169

   Insert

   CHARMS-V43D/E52K/R62E
   

   Use

   Lentiviral

   Tags

   mEGFP

   Expression

   Mammalian

   Promoter

   SV40

   Available Since

   April 28, 2025

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

2. pHRSV_CHARMS-1xA

   Plasmid

   #233924

   Purpose

   Mammalian expression of Chimeric Higher-Order Assemblies for Receptor Mediated Signaling (CHARMS) variant: CHARMS-1xA which contains 1 TRAF6 binding motif with a alanine mutation

   Depositor

   Marcus Taylor

   Article

   Lichtenstein et al bioRxiv 2024.05.08.593169

   Insert

   CHARMS-1xA
   

   Use

   Lentiviral

   Tags

   mEGFP

   Expression

   Mammalian

   Promoter

   SV40

   Available Since

   April 28, 2025

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

3. pHRSV_CHARMS-3xA

   Plasmid

   #233926

   Purpose

   Mammalian expression of Chimeric Higher-Order Assemblies for Receptor Mediated Signaling (CHARMS) variant: CHARMS-3xA which contains 3 TRAF6 binding motif with a alanine mutation

   Depositor

   Marcus Taylor

   Article

   Lichtenstein et al bioRxiv 2024.05.08.593169

   Insert

   CHARMS-3xA
   

   Use

   Lentiviral

   Tags

   mEGFP

   Expression

   Mammalian

   Promoter

   SV40

   Available Since

   April 28, 2025

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

4. pHRSV_CHARMS-5xA

   Plasmid

   #233928

   Purpose

   Mammalian expression of Chimeric Higher-Order Assemblies for Receptor Mediated Signaling (CHARMS) variant: CHARMS-5xA which contains only 5 TRAF6 binding motifs with a alanine mutation

   Depositor

   Marcus Taylor

   Article

   Lichtenstein et al bioRxiv 2024.05.08.593169

   Insert

   CHARMS-5xA
   

   Use

   Lentiviral

   Tags

   mEGFP

   Expression

   Mammalian

   Promoter

   SV40

   Available Since

   April 28, 2025

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

5. pHRSV_CHARMS-S34Y

   Plasmid

   #233929

   Purpose

   Mammalian expression of Chimeric Higher-Order Assemblies for Receptor Mediated Signaling (CHARMS) variant: CHARMS-S34Y which contains a mutation in the death domain that disrupt oligomer formation

   Depositor

   Marcus Taylor

   Article

   Lichtenstein et al bioRxiv 2024.05.08.593169

   Insert

   CHARMS-S34Y
   

   Use

   Lentiviral

   Tags

   mEGFP

   Expression

   Mammalian

   Promoter

   SV40

   Available Since

   April 28, 2025

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

6. pHRSV_CHARMS-17xTA-3xAla

   Plasmid

   #233936

   Purpose

   Mammalian expression of Chimeric Higher-Order Assemblies for Receptor Mediated Signaling (CHARMS) variant: CHARMS-17xTA with alanine mutation in the TRAF6 binding motif

   Depositor

   Marcus Taylor

   Article

   Lichtenstein et al bioRxiv 2024.05.08.593169

   Insert

   CHARMS-17xTA-3xA
   

   Use

   Lentiviral

   Tags

   mEGFP

   Expression

   Mammalian

   Promoter

   SV40

   Available Since

   April 28, 2025

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

7. pHRSV_CHARMS-20xTA-3xAla

   Plasmid

   #233937

   Purpose

   Mammalian expression of Chimeric Higher-Order Assemblies for Receptor Mediated Signaling (CHARMS) variant: CHARMS-20xTA with alanine mutation in the TRAF6 binding motif

   Depositor

   Marcus Taylor

   Article

   Lichtenstein et al bioRxiv 2024.05.08.593169

   Insert

   CHARMS-20xTA-20xA
   

   Use

   Lentiviral

   Tags

   mEGFP

   Expression

   Mammalian

   Promoter

   SV40

   Available Since

   April 28, 2025

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

8. pHRSV_CHARMS-TIR-5xT6BMs

   Plasmid

   #233938

   Purpose

   Mammalian expression of Chimeric Higher-Order Assemblies for Receptor Mediated Signaling (CHARMS) variant: CHARMS-TIR with 5 TRAF6 binding motifs

   Depositor

   Marcus Taylor

   Article

   Lichtenstein et al bioRxiv 2024.05.08.593169

   Insert

   CHARMS-TIR-5xT6BMs
   

   Use

   Lentiviral

   Tags

   mEGFP

   Expression

   Mammalian

   Promoter

   SV40

   Available Since

   April 28, 2025

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

9. pHR_CMV_MeltCasp1-37-GFP

   Plasmid

   #234069

   Purpose

   Encodes the caspase1 without CARD domain (with R391K mutation) controlled by a Melt variant with a switching temperature of 37°C

   Depositor

   Lukasz Bugaj

   Article

   Benman et al Nat Methods. 2025 Jan 23. doi: 10.1038/s

   Insert

   MeltCasp1-37-GFP
   

   Use

   Lentiviral

   Expression

   Mammalian

   Mutation

   Melt(C292A,Q355N); hcaspase1(R391K)

   Promoter

   CMV

   Available Since

   April 3, 2025

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

10. pAF125

    Plasmid

    #222373

    Purpose

    Recombinant human IgG antibody vector without variable regions. Contains mTagBFP marker.

    Depositor

    Andrew S. Flies

    Article

    Slyp et al Methods Mol Biol. 2024;2826:231-249. doi

    Insert

    IGHG (partial)
    

    Use

    Affinity Reagent/ Antibody

    Expression

    Mammalian

    Promoter

    EF1a

    Available Since

    Aug. 14, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

11. pLPC-C-SF-TAP-DEST-TLK1- M566T

    Plasmid

    #218831

    Purpose

    Expresses C-terminal Strep-FLAG-tagged M566T human TLK1 variant 5 in a retrovirus vector.

    Depositor

    Travis Stracker

    Insert

    TLK1 M566T (TLK1 Human)
    

    Tags

    FLAG-STREP

    Expression

    Mammalian

    Mutation

    M566T

    Promoter

    CMV

    Available Since

    July 24, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

12. pcDNA3.1-msEGFP1.8

    Plasmid

    #208619

    Purpose

    Mammalian expression of a EGFP variant. Mutations were adopted from (Addgene#135301, PMC7508230), named msEGFP1.8 because N-ter and C-ter features of that in msGFP2 (PMC7508230) not included.

    Depositor

    Quanfu Ma

    Insert

    msEGFP1.8
    

    Expression

    Mammalian

    Mutation

    (compared with pEGFP-C1, protein level) S30R, Y39…

    Promoter

    CMV

    Available Since

    Jan. 9, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

13. pTrc-CysGA-Im7 F84A

    Plasmid

    #201082

    Purpose

    Im7 F84A variant inserted into CysGA at G364 via GS linker

    Depositor

    Shu Quan

    Article

    Ren et al Proc Natl Acad Sci U S A. 2021 Mar 30;11

    Insert

    CysGA-Im7 F84A
    

    Expression

    Bacterial

    Mutation

    Im7 F84A

    Promoter

    pTrc

    Available Since

    Sept. 27, 2023

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

14. pGL0_18 [AMA1 long ORI]

    Plasmid

    #198931

    Purpose

    Level 0 part

    Depositor

    Charlie Gilbert, Nili Ostrov, Cultivarium Tools

    Article

    Gilbert et al bioRxiv 2023.05.19.541510

    Insert

    AMA1 long ORI
    

    Use

    Synthetic Biology

    Available Since

    Sept. 5, 2023

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

15. pGL0_15 [CEN6/ARSH4 ORI]

    Plasmid

    #198928

    Purpose

    Level 0 part

    Depositor

    Charlie Gilbert, Nili Ostrov, Cultivarium Tools

    Article

    Gilbert et al bioRxiv 2023.05.19.541510

    Insert

    CEN6/ARSH4 ORI
    

    Use

    Synthetic Biology

    Available Since

    July 18, 2023

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

16. pGL2_175

    Plasmid

    #199107

    Purpose

    Level 2 plasmid, barcoded ORI with gentamicin resistance cassette and mScarlet-I reporter

    Depositor

    Charlie Gilbert, Nili Ostrov, Cultivarium Tools

    Article

    Gilbert et al bioRxiv 2023.05.19.541510

    Insert

    Dummy ORI plus NGS barcode 23, gentamicin resistance cassette, mScarlet-I cassette, oriT
    

    Use

    Synthetic Biology

    Available Since

    June 27, 2023

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

17. pGL2_172

    Plasmid

    #199104

    Purpose

    Level 2 plasmid, barcoded ORI with gentamicin resistance cassette and mScarlet-I reporter

    Depositor

    Charlie Gilbert, Nili Ostrov, Cultivarium Tools

    Article

    Gilbert et al bioRxiv 2023.05.19.541510

    Insert

    pSG5 ORI plus NGS barcode 20, gentamicin resistance cassette, mScarlet-I cassette, oriT
    

    Use

    Synthetic Biology

    Available Since

    June 27, 2023

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

18. Paxillin DN

    Plasmid

    #186151

    Purpose

    For expressing recombinant paxillin variants in bacteria.

    Depositor

    Michael Rosen

    Article

    Case et al Elife. 2022 Jan 20;11. pii: 72588. doi:

    Insert

    PXN (PXN Human)
    

    Tags

    GST

    Expression

    Bacterial

    Mutation

    Paxilln residues 1-321 added to N-terminus of WT …

    Promoter

    Lac

    Available Since

    June 30, 2022

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

19. pAc5.1B-EGFP-HsTNRC6C_L

    Plasmid

    #146855

    Purpose

    Insect Expression of HsTNRC6C

    Depositor

    Elisa Izaurralde

    Article

    Huntzinger et al EMBO J. 2010 Dec 15;29(24):4146-60. doi:

    Insert

    HsTNRC6C (TNRC6C Human)
    

    Expression

    Insect

    Mutation

    one non silent mutation Q1183K compard to the seq…

    Available Since

    May 13, 2022

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

20. MSCV-mouse Mdm2 mutant M3 (399-489)-IRES-GFP

    Plasmid

    #180490

    Purpose

    Role of Mdm2 variants in tumorigenesis

    Depositor

    Martine Roussel

    Article

    Dang et al Cancer Res. 2002 Feb 15;62(4):1222-30.

    Inserts

    Mouse Mdm2 mutant
    Mouse Mdm2 mutant
    

    Expression

    Mammalian

    Mutation

    399-489

    Promoter

    MSCV

    Available Since

    March 29, 2022

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

21. MSCV-mouse Mdm2 mutant M2 (299-489)-IRES-GFP

    Plasmid

    #180489

    Purpose

    Role of Mdm2 variants in tumorigenesis

    Depositor

    Martine Roussel

    Article

    Dang et al Cancer Res. 2002 Feb 15;62(4):1222-30.

    Insert

    Mouse Mdm2 mutant
    

    Use

    Retroviral

    Expression

    Mammalian

    Mutation

    299-489

    Promoter

    MSCV

    Available Since

    March 29, 2022

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

22. CD44U-c010

    Plasmid

    #175453

    Purpose

    Protein expression/secretion in mammalian cells. CD44 splice variant 10 (exons 2-5, 11, 15-16), A20-E649.

    Depositor

    Opher Gileadi

    Insert

    CD44 (CD44 Human)
    

    Tags

    His6

    Expression

    Mammalian

    Available Since

    Jan. 27, 2022

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

23. pJH76

    Plasmid

    #172144

    Purpose

    Accessory Plasmid for PACE of pylBCD variants

    Depositor

    Matthew Bennett

    Article

    Ho et al Nat Commun. 2021 Jun 24;12(1):3914. doi:

    Insert

    Ppsp gIII.2TAG, luxAB; Plpp pylS; PproK pylT
    

    Expression

    Bacterial

    Mutation

    gIII(P29*, Y184*)

    Available Since

    Nov. 30, 2021

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

24. pJH578

    Plasmid

    #172162

    Purpose

    pylBCD variant in pBAD backbone

    Depositor

    Matthew Bennett

    Article

    Ho et al Nat Commun. 2021 Jun 24;12(1):3914. doi:

    Insert

    Para (pylBCD 3f2_v2); AraC
    

    Expression

    Bacterial

    Mutation

    PylB(N61S, E84K, E122K, E178K, G188R, E251D) PylC…

    Available Since

    Sept. 24, 2021

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

25. pJH581

    Plasmid

    #172165

    Purpose

    pylBCD variant in pBAD backbone

    Depositor

    Matthew Bennett

    Article

    Ho et al Nat Commun. 2021 Jun 24;12(1):3914. doi:

    Insert

    Para (pylBCD 3f2+C); AraC
    

    Expression

    Bacterial

    Mutation

    PylB(N61S, E84K, E122K, E178K, G188R, E251D) PylC…

    Available Since

    Sept. 24, 2021

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

26. pJH223

    Plasmid

    #172151

    Purpose

    pylBCD variant in pCDF backbone

    Depositor

    Matthew Bennett

    Article

    Ho et al Nat Commun. 2021 Jun 24;12(1):3914. doi:

    Insert

    PT7/lac (pylBCD 34B_sub-pop5); LacI
    

    Expression

    Bacterial

    Mutation

    PylB(N61S, E178K, E251D) PylD(A252V)

    Available Since

    Sept. 24, 2021

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

27. pJH224

    Plasmid

    #172152

    Purpose

    pylBCD variant in pCDF backbone

    Depositor

    Matthew Bennett

    Article

    Ho et al Nat Commun. 2021 Jun 24;12(1):3914. doi:

    Insert

    PT7/lac (pylBCD 40C_sub-pop6); LacI
    

    Expression

    Bacterial

    Mutation

    PylB(N61S, E175K, E178K)

    Available Since

    Sept. 24, 2021

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

28. pJH463

    Plasmid

    #172155

    Purpose

    pylBCD variant in pBAD backbone

    Depositor

    Matthew Bennett

    Article

    Ho et al Nat Commun. 2021 Jun 24;12(1):3914. doi:

    Insert

    Para (pylBCD 36A_sub-pop1); AraC
    

    Expression

    Bacterial

    Mutation

    PylB(N61S, E122K, E178K, G188R)

    Available Since

    Sept. 24, 2021

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

29. pJH573

    Plasmid

    #172157

    Purpose

    pylBCD variant in pBAD backbone

    Depositor

    Matthew Bennett

    Article

    Ho et al Nat Commun. 2021 Jun 24;12(1):3914. doi:

    Insert

    Para (Untagged pylBCD); AraC
    

    Expression

    Bacterial

    Mutation

    Codon-optimized Methanosarcina acetivorans pylBCD

    Available Since

    Sept. 24, 2021

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

30. pJH574

    Plasmid

    #172158

    Purpose

    pylBCD variant in pBAD backbone

    Depositor

    Matthew Bennett

    Article

    Ho et al Nat Commun. 2021 Jun 24;12(1):3914. doi:

    Insert

    Para (pylBCD 36A_sub-pop2); AraC
    

    Expression

    Bacterial

    Mutation

    PylB(N61S, E84K, E122K) PylC(E316D)

    Available Since

    Sept. 24, 2021

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge