Purpose
vector for encoding an engineered glycosylase-based guanine base editor (gGBEv6.3) with SpG nickase driven by EF1a promoter, guide RNA compatible with SpG driven by hU6, mCherry driven by CBh promoter
Insert
nSpG(D10A)-MPGv6.3
Mutation
SpG = D1135L, S1136W, G1218K, E1219Q, R1335Q, T13…
Available Since
June 27, 2023
Availability
Academic Institutions and Nonprofits only