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pTE_23 - pDonor_TRAC-2a-FMC6.3-BBz-2a

Plasmid

#252019

Purpose

Donor for CD19 CAR knock-in at TRAC locus

Depositor

Neville Sanjana

Article

Burrell et al bioRxiv 2026.02.19.706875

Insert

2a-FMC6.3-BBz-2a

Use

Unspecified

Mutation

NA

Available Since

March 4, 2026

Availability

Academic Institutions and Nonprofits only

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pTE_15 - pCMV-Cas9-XTEN-ZRANB3

Plasmid

#252011

Purpose

Mammalian expression of Cas9-ZRANB3 TruEditor

Depositor

Neville Sanjana

Article

Burrell et al bioRxiv 2026.02.19.706875

Insert

Cas9-ZRANB3

Use

CRISPR

Expression

Mammalian

Mutation

NA

Available Since

March 3, 2026

Availability

Academic Institutions and Nonprofits only

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pTE_12 - pCMV-Cas9-XTEN-SLX1A

Plasmid

#252008

Purpose

Mammalian expression of Cas9-SLX1A TruEditor

Depositor

Neville Sanjana

Article

Burrell et al bioRxiv 2026.02.19.706875

Insert

Cas9-SLX1A

Use

CRISPR

Expression

Mammalian

Mutation

NA

Available Since

March 3, 2026

Availability

Academic Institutions and Nonprofits only

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pTE_11 - pCMV-Cas9-XTEN-BARD1

Plasmid

#252007

Purpose

Mammalian expression of Cas9-BARD1 TruEditor

Depositor

Neville Sanjana

Article

Burrell et al bioRxiv 2026.02.19.706875

Insert

Cas9-BARD1

Use

CRISPR

Expression

Mammalian

Mutation

NA

Available Since

March 3, 2026

Availability

Academic Institutions and Nonprofits only

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pTE_07 - pLenti_EFS-Cas9-XTEN-FEN1-2A-BlastR

Plasmid

#252003

Purpose

Lentiviral mammalian expression of Cas9-FEN1 TruEditor

Depositor

Neville Sanjana

Article

Burrell et al bioRxiv 2026.02.19.706875

Insert

Cas9-FEN1

Use

CRISPR and Lentiviral

Mutation

NA

Available Since

March 3, 2026

Availability

Academic Institutions and Nonprofits only

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pTE_06 - pLenti_EFS-Cas9-XTEN-RAD18-2A-BlastR

Plasmid

#252002

Purpose

Lentiviral mammalian expression of Cas9-RAD18 TruEditor

Depositor

Neville Sanjana

Article

Burrell et al bioRxiv 2026.02.19.706875

Insert

Cas9-RAD18

Use

CRISPR and Lentiviral

Mutation

NA

Available Since

March 3, 2026

Availability

Academic Institutions and Nonprofits only

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pTE_05 - pLenti_EFS-Cas9-XTEN-SLX1A-2A-BlastR

Plasmid

#252001

Purpose

Lentiviral mammalian expression of Cas9-SLX1A TruEditor

Depositor

Neville Sanjana

Article

Burrell et al bioRxiv 2026.02.19.706875

Insert

Cas9-SLX1A

Use

CRISPR and Lentiviral

Mutation

NA

Available Since

March 3, 2026

Availability

Academic Institutions and Nonprofits only

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pTE_04 - pLenti_EFS-Cas9-XTEN-ZNF146-2A-BlastR

Plasmid

#252000

Purpose

Lentiviral mammalian expression of Cas9-ZNF146 TruEditor

Depositor

Neville Sanjana

Article

Burrell et al bioRxiv 2026.02.19.706875

Insert

Cas9-ZNF146

Use

CRISPR and Lentiviral

Mutation

NA

Available Since

March 3, 2026

Availability

Academic Institutions and Nonprofits only

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pTE_03 - pLenti_EFS-Cas9-XTEN-BARD1-2A-BlastR

Plasmid

#251999

Purpose

Lentiviral mammalian expression of Cas9-BARD1 TruEditor

Depositor

Neville Sanjana

Article

Burrell et al bioRxiv 2026.02.19.706875

Insert

Cas9-BARD1

Use

CRISPR and Lentiviral

Mutation

NA

Available Since

March 3, 2026

Availability

Academic Institutions and Nonprofits only

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pTE_01 - pLenti_EFS-Cas9-XTEN-ZRANB3-2A-BlastR

Plasmid

#251997

Purpose

Lentiviral mammalian expression of Cas9-ZRANB3 TruEditor

Depositor

Neville Sanjana

Article

Burrell et al bioRxiv 2026.02.19.706875

Insert

Cas9-ZRANB3

Use

CRISPR and Lentiviral

Mutation

NA

Available Since

March 3, 2026

Availability

Academic Institutions and Nonprofits only

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pAC-U63-gRNA2.1-tub-miRFP680-T2A-HO1(HA)

Plasmid

#250795

Purpose

Drosophila transgenic vector: nMAGIC vector with tub promoter, 3x HA tags, miRFP680, and HO1. Optimized nMAGIC vector with a far red/infra red FP marker.

Depositor

Chun Han

Article

Shen et al Elife. 2026 Mar 11;14:RP108453. doi: 10.

Type

Empty backbone

Use

CRISPR

Expression

Insect

Available Since

Feb. 18, 2026

Availability

Academic Institutions and Nonprofits only

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pYPQ134B-TLS

Plasmid

#245879

Purpose

Golden gate entry vector carrying TLS mobile RNA sequence

Depositor

Yiping Qi

Article

Rocha et al Plant Cell Rep. 2025 Oct 22;44(11):244.

Insert

TLS2

Use

CRISPR and Synthetic Biology

Expression

Plant

Promoter

AtU3

Available Since

Feb. 2, 2026

Availability

Academic Institutions and Nonprofits only

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pYPQ133B-TLS

Plasmid

#245882

Purpose

Golden gate entry vector carrying TLS mobile RNA sequence

Depositor

Yiping Qi

Article

Rocha et al Plant Cell Rep. 2025 Oct 22;44(11):244.

Insert

TLS2

Use

CRISPR and Synthetic Biology

Expression

Plant

Promoter

AtU3

Available Since

Feb. 2, 2026

Availability

Academic Institutions and Nonprofits only

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pYPQ131-FCY-UPP

Plasmid

#245873

Purpose

Golden gate entry vector carrying expression cassette for genes FCY and UPP

Depositor

Yiping Qi

Article

Rocha et al Plant Cell Rep. 2025 Oct 22;44(11):244.

Insert

FCY1-UPP

Use

CRISPR

Expression

Plant

Promoter

AtUBQ10

Available Since

Feb. 2, 2026

Availability

Academic Institutions and Nonprofits only

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pAcr

Plasmid

#207570

Purpose

AcrIIC1-mediated inhibition of ThermoCas9 and GeoCas9 cleavage activity in E. coli

Depositor

John van der Oost

Article

Trasanidou et al Commun Biol. 2023 Oct 13;6(1):1042. doi:

Insert

Prha_AcrIIC1Nme

Expression

Bacterial

Mutation

Wild-type

Available Since

Dec. 17, 2025

Availability

Academic Institutions and Nonprofits only

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pU6_H1-g3

Plasmid

#247169

Purpose

U6 driven gRNA expression of H1-g3 for targeting Dn29 attH1

Depositor

Patrick Hsu

Article

Fanton et al Nat Biotechnol. 2025 Nov 6. doi: 10.1038

Insert

H1-g3

Expression

Mammalian

Promoter

U6

Available Since

Nov. 4, 2025

Availability

Academic Institutions and Nonprofits only

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pVTCL1

Plasmid

#234919

Purpose

All-in-one subcellar localization vector. Construct containing EGFP tag and cell nucleus-targeted mCherry for co-localization study in plants.

Depositor

Guoli Song

Article

Hao et al Plant Commun. 2025 May 19:101379. doi: 1

Type

Empty backbone

Expression

Plant

Available Since

Sept. 23, 2025

Availability

Academic Institutions and Nonprofits only

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pEM9_CL7_Bac_2NLS-iCas12a (LbCas12a)-4NLS

Plasmid

#244844

Purpose

Bacterial expression of iCas12a LbCas12a with 2xSV40 nuclear localization sequence for protein purification

Depositor

Jennifer Doudna

Article

Ma et al Nucleic Acids Res. 2025 Jul 8;53(13):gka

Insert

iCas12a

Use

CRISPR

Tags

10xHis-CL7-2xSV40 NLS and 4xSV40 NLS

Expression

Bacterial

Mutation

F863V/D952N/C965Y/V1011A/Q1108L/A1113V/S1132T/S12…

Promoter

T7

Available Since

Sept. 17, 2025

Availability

Academic Institutions and Nonprofits only

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pEM5_CL7_Bac_2NLS-Lbm6 (LbCas12a)-4NLS

Plasmid

#244840

Purpose

Bacterial expression of Lbm6 LbCas12a with 2xSV40 NLS at N-terminus and 4xSV40 at C-terminus

Depositor

Jennifer Doudna

Article

Ma et al Nucleic Acids Res. 2025 Jul 8;53(13):gka

Insert

Lbm6-Cas12a

Use

CRISPR

Tags

10xHis-CL7-2xSV40 NLS and 4xSV40 NLS

Expression

Bacterial

Mutation

D535G/S551F/D665N

Promoter

T7

Available Since

Sept. 17, 2025

Availability

Academic Institutions and Nonprofits only

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pHS641_Flex-Cas12a-ABE

Plasmid

#244846

Purpose

Mammalian expression of Flex-Cas12a adenine base editor

Depositor

Jennifer Doudna

Article

Ma et al Nucleic Acids Res. 2025 Jul 8;53(13):gka

Insert

Flex-dCas12a-ABE

Use

CRISPR

Tags

SV40 NLS-ABE8e

Expression

Mammalian

Mutation

G146R/R182V/D535G/S551F/D665N/E795Q/D832A

Promoter

CMV

Available Since

Sept. 16, 2025

Availability

Academic Institutions and Nonprofits only

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