We narrowed to 10,556 results for: aav

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Redi.1.SaCas9-L9A-I934T-L1035A

Plasmid

#235230

Purpose

Expresses reduced immunogenicity variant of SaCas9 (Redi.1.SaCas9) with mutations L9A, I934T, L1035A. Has AAV ITRs

Depositor

Feng Zhang

Publication

Raghavan et al Nat Commun. 2025 Jan 2;16(1):105. doi: 1

Insert

hSaCas9

Use

AAV and CRISPR

Expression

Mammalian

Available since

June 29, 2026

Availability

Academic Institutions and Nonprofits only

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Redi.2.SaCas9-L9S-I934K-L1035V

Plasmid

#235231

Purpose

Expresses reduced immunogenicity variant of SaCas9 (Redi.2.SaCas9) with mutations L9S, I934K, L1035V. Has AAV ITRs

Depositor

Feng Zhang

Publication

Raghavan et al Nat Commun. 2025 Jan 2;16(1):105. doi: 1

Insert

hSaCas9

Use

AAV and CRISPR

Expression

Mammalian

Mutation

changed L9S, I934K, L1035V

Available since

June 23, 2026

Availability

Academic Institutions and Nonprofits only

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pEJS1553 pLenti-U1a-SpCas9-miniU6-tracrRNA

Plasmid

#211819

Purpose

lentiviral vector expressing SpCas9 and tracrRNA for stable cell line extablishment

Depositor

Erik Sontheimer

Publication

Zhang et al Nucleic Acids Res. 2023 Nov 30:gkad1125.

Insert

SpCas9, tracrRNA and blasticidin resistance gene

Use

Lentiviral

Expression

Mammalian

Promoter

U1a promoter and miniU6 promoter

Available since

Jan. 10, 2024

Availability

Academic Institutions and Nonprofits only

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pEJS1983 Lenti-dead_GFP_ABE reporter-BlastR

Plasmid

#211820

Purpose

Lentiviral vector expressing a dead GFP adenine base editing reporter

Depositor

Erik Sontheimer

Publication

Zhang et al Nucleic Acids Res. 2023 Nov 30:gkad1125.

Insert

dead GFP reporter

Use

Lentiviral

Expression

Mammalian

Promoter

CMV promoter and SV40 promoter

Available since

Jan. 10, 2024

Availability

Academic Institutions and Nonprofits only

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pEJS-HZ03-pLenti-U1a-mSpCas9-U6-tracrRNA-PuroR

Plasmid

#211815

Purpose

lentiviral vector expressing SpCas9 and tracrRNA for stable cell line establishment

Depositor

Erik Sontheimer

Publication

Zhang et al Nucleic Acids Res. 2023 Nov 30:gkad1125.

Insert

SpCas9, tracrRNA and puromycin selection gene

Use

Lentiviral

Expression

Mammalian

Promoter

U1a promoter, U6 promoter, and hPGK promoter

Available since

Jan. 10, 2024

Availability

Academic Institutions and Nonprofits only

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pEMS2023

Plasmid

#49130

Purpose

AAV plasmid with hs1218 promoter driving expression of iCre.

Depositor

Elizabeth Simpson

Publication

Simpson et al Hum Gene Ther. 2018 Jul 31. doi: 10.1089

Insert

ssAAV-hs1218-iCre

Use

AAV

Expression

Mammalian

Promoter

hs1218

Available since

May 10, 2016

Availability

Industry, Academic Institutions, and Nonprofits

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pEMS2024

Plasmid

#49131

Purpose

AAV plasmid with hs671 promoter driving expression of iCre.

Depositor

Elizabeth Simpson

Publication

Simpson et al Hum Gene Ther. 2018 Jul 31. doi: 10.1089

Insert

ssAAV-hs671-iCre

Use

AAV

Expression

Mammalian

Promoter

hs671

Available since

May 10, 2016

Availability

Industry, Academic Institutions, and Nonprofits

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pEMS2025

Plasmid

#49132

Purpose

AAV plasmid with NOV (Ple303) promoter driving expression of iCre.

Depositor

Elizabeth Simpson

Publication

Simpson et al Hum Gene Ther. 2018 Jul 31. doi: 10.1089

Insert

ssAAV-Ple303-iCre

Use

AAV

Expression

Mammalian

Promoter

NOV

Available since

May 10, 2016

Availability

Industry, Academic Institutions, and Nonprofits

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pCI108-SiT-Cas12a-[Cond]

Plasmid

#128407

Purpose

Conditionally express both AsCas12a and CRISPR arrays on single transcripts

Depositor

Randall Platt

Publication

Campa et al Nat Methods. 2019 Aug 12. pii: 10.1038/s

Insert

AsCas12a-Triplex

Use

AAV

Expression

Mammalian

Available since

Nov. 1, 2019

Availability

Academic Institutions and Nonprofits only

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shNg pA_RC3J1_CAGW

Plasmid

#92155

Purpose

Bicistronic AAV construct encoding GFP control and shRNA targeting Ng

Depositor

Weifeng Xu

Publication

Han et al Cell Rep. 2017 Jan 24;18(4):892-904. doi

Insert

shRNA targeting Ng (NRGN Human)

Use

AAV

Expression

Mammalian

Promoter

H1

Available since

March 22, 2019

Availability

Academic Institutions and Nonprofits only

Cited by

1 Article

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MS2_adRNA-MCP_ADAR2 DD (E488Q)_NES

Plasmid

#124707

Purpose

Expresses MS2_adRNA targeting the RAB7A transcript along with the MCP_ADAR2 DD(E488Q)_NES

Depositor

Prashant Mali

Publication

Katrekar et al Nat Methods. 2019 Mar;16(3):239-242. doi

Insert

MCP_ADAR2 DD (E488Q)_NES

Use

AAV

Tags

NES

Expression

Mammalian

Mutation

E488Q hyperactive mutant

Promoter

CMV

Available since

Sept. 26, 2019

Availability

Academic Institutions and Nonprofits only

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pSaCas9-1xPP7-2x3'UTR

Plasmid

#122947

Purpose

For expressing SaCas9 mRNA with one copy of PP7 aptamer and 2 copies of HBB 3' UTR

Depositor

Baisong Lu

Publication

Lu et al Nucleic Acids Res. 2019 Feb 13. pii: 531

Insert

SaCas9-PP7-HBB 3' UTR

Use

AAV

Expression

Mammalian

Available since

May 15, 2019

Availability

Academic Institutions and Nonprofits only

Cited by

1 Article

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pCAG-SpCas9-2A-GFP-noITR

Plasmid

#118415

Purpose

Cas9 GFP plasmid constitutively expressed from CAG promoter. AAV repeat region removed to increase expression

Depositor

Mark Denham

Publication

Hojland Knudsen et al Front Cell Dev Biol. 2018 May 15;6:54. d

Insert

Cas9

Use

CRISPR

Expression

Mammalian

Available since

Nov. 13, 2018

Availability

Academic Institutions and Nonprofits only

Cited by

1 Article

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MKC62_HBB(HBA1reg-HBA1-2A-YFP)

Plasmid

#232408

Purpose

AAV production plasmid for HBA1-2A-YFP vector from Fig. 2 that mediates HDR at HBB locus using HBB sg7 gRNA. HBA gene includes HBA1 exons and introns; HBA1 UTRs flank full HBA1-2A-YFP cassette.

Depositor

Kyle Cromer

Publication

Chu et al bioRxiv [Preprint]. 2024 May 7:2023.09.0

Insert

Hemoglobin Subunit Alpha 1 (HBA1 Human)

Use

AAV

Expression

Mammalian

Available since

April 18, 2025

Availability

Academic Institutions and Nonprofits only

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pyc111f

Plasmid

#158780

Purpose

ribosome-tagged, Cre-dependent GCaMP for soma localization

Depositor

Jennifer Garrison, Zachary Knight

Publication

Chen et al Neuron. 2020 Jun 5. pii: S0896-6273(20)3

Insert

GCaMP6f-RPL10a

Use

AAV

Available since

Sept. 28, 2020

Availability

Academic Institutions and Nonprofits only

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pCAG-mRhubarb720

Plasmid

#197212

Purpose

Expresses the protein of mRhubarb720 in mammalian cells

Depositor

Kiryl Piatkevich

Publication

Zhang et al Nat Methods. 2023 Sep 4. doi: 10.1038/s4

Insert

mRhubarb720

Use

AAV

Available since

Aug. 7, 2023

Availability

Academic Institutions and Nonprofits only

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UPB-colon (UPB4)

Plasmid

#180786

Purpose

Unique Projection Barcode (UPB4)-Colon for Projection-seq

Depositor

Rui Chang

Publication

Zhao et al Nature. 2022 Mar;603(7903):878-884. doi:

Insert

hM3Dq ( partial )

Use

AAV

Expression

Mammalian

Promoter

CAG

Available since

Aug. 15, 2022

Availability

Academic Institutions and Nonprofits only

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mDlx-SynTagMA_post-2A-mCerulean

Plasmid

#130899

Purpose

Synaptic Tag for Mapping Activity in GABAergic neurons

Depositor

Simon Wiegert

Publication

Perez-Alvarez et al Nat Commun. 2020 May 18;11(1):2464. doi:

Insert

SynTagMA

Use

AAV

Tags

mCerulean

Expression

Mammalian

Promoter

mDlx

Available since

Sept. 13, 2019

Availability

Academic Institutions and Nonprofits only

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hSyn-DIO-BiPOLES-mCerulean

Plasmid

#154950

Purpose

Optogenetic tool for blue-light inhibition and red-light excitation of neurons

Depositor

Simon Wiegert

Publication

Vierock et al Nat Commun. 2021 Jul 26;12(1):4527. doi:

Insert

BiPOLES

Use

AAV

Expression

Mammalian

Promoter

human synapsin

Available since

Aug. 18, 2020

Availability

Academic Institutions and Nonprofits only

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PZac2.1 hSyn1-Lck-13xLinker-BioID2-BioID2-HA

Plasmid

#176854

Purpose

Expresses membrane bound biotin ligase, BioID2, in neurons

Depositor

Baljit Khakh

Publication

Soto et al Nature. 2023 Apr;616(7958):764-773. doi:

Insert

Lck-13xLinker-BioID2-BioID2-HA

Use

AAV

Tags

HA

Expression

Bacterial

Promoter

hSyn1

Available since

April 11, 2023

Availability

Academic Institutions and Nonprofits only

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