We narrowed to 9,263 results for: CAG

1. pLKO.1-puro-shWRN1

   Plasmid

   #125781

   Purpose

   constitutive expression of a short-hairpin RNA targeting human WRN

   Depositor

   Francisca Vazquez

   Article

   Chan et al Nature. 2019 Apr 10. pii: 10.1038/s41586

   Insert

   shWRN1 (WRN Human)
   

   Use

   RNAi

   Available Since

   May 29, 2019

   Availability

   Academic Institutions and Nonprofits only

   

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2. pKLV2-U6gRNA5(SOX2_v32_7-4)-PGKpuroBFP-W

   Plasmid

   #211986

   Purpose

   Express gRNA against SOX2 with puro and BFP

   Depositor

   Kosuke Yusa

   Article

   Ishikawa et al Commun Biol. 2023 Dec 28;6(1):1290. doi:

   Insert

   sgRNA targeting SOX2 (SOX2 Human)
   

   Use

   CRISPR and Lentiviral

   Expression

   Mammalian

   Promoter

   Human U6 promoter

   Available Since

   Jan. 24, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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3. pMXS-IRES-BLAST flag-CAD hCPS1 AD

   Plasmid

   #188130

   Purpose

   Expresses C-terminal flag-tagged human CAD hCPS1 AD in mammalian cells

   Depositor

   Richard Possemato

   Article

   Shin et al Nat Metab. 2023 Feb 6. doi: 10.1038/s422

   Insert

   CAD (CAD Human)
   

   Use

   Retroviral

   Tags

   Flag tag

   Expression

   Mammalian

   Mutation

   TCC -> AGT silent mutations at nt439-441 elimi…

   Available Since

   Feb. 6, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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4. B52 + CHEK2 sgSTOP

   Plasmid

   #100712

   Purpose

   B52 plasmid expressing CHEK2 sgSTOP (cloned in BbsI site) and containing an empty sgRNA-expression cassette (use BsmBI for cloning)

   Depositor

   Alberto Ciccia

   Article

   Billon et al Mol Cell. 2017 Sep 4. pii: S1097-2765(17

   Insert

   sgSTOP targeting CHEK2 (cloned using BbsI) (CHEK2 Human)
   

   Use

   CRISPR

   Expression

   Mammalian

   Promoter

   U6 promoters

   Available Since

   Sept. 6, 2017

   Availability

   Academic Institutions and Nonprofits only

   

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5. pLKO.1-puro-shWRN2

   Plasmid

   #125782

   Purpose

   constitutive expression of a short-hairpin RNA targeting human WRN

   Depositor

   Francisca Vazquez

   Article

   Chan et al Nature. 2019 Apr 10. pii: 10.1038/s41586

   Insert

   shWRN2 (WRN Human)
   

   Use

   RNAi

   Available Since

   June 27, 2019

   Availability

   Academic Institutions and Nonprofits only

   

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6. pGEX-2TK-arc105

   Plasmid

   #133425

   Purpose

   Human ARC105 coding sequence in vector for bacterial expression of GST fusion protein.

   Depositor

   Gerhard Wagner

   Article

   Yang et al Nature. 2006 Aug 10;442(7103):700-4. doi

   Insert

   PCQAP (MED15 Human)
   

   Expression

   Bacterial

   Mutation

   Contains amino acids 1-95 or ARC105 fused to the …

   Available Since

   Jan. 6, 2020

   Availability

   Academic Institutions and Nonprofits only

   

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7. sgCRY1

   Plasmid

   #176511

   Purpose

   Expresses sgRNA in mammalian cells

   Depositor

   Han Kyoung Choe

   Article

   Kim et al Sci Rep. 2021 Jan 28;11(1):2575. doi: 10

   Insert

   hU6-sgCRY1-2 (Cry1, Cry2 Mouse)
   

   Use

   AAV

   Tags

   mCherry (K14E, N210D, E249G)

   Promoter

   U6, hSyn

   Available Since

   Jan. 5, 2022

   Availability

   Academic Institutions and Nonprofits only

   

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8. CHUK gRNA (BRDN0001148194)

   Plasmid

   #77035

   Purpose

   3rd generation lentiviral gRNA plasmid targeting human CHUK

   Depositor

   John Doench, David Root

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Insert

   CHUK (CHUK Human)
   

   Use

   CRISPR and Lentiviral

   Expression

   Mammalian

   Promoter

   hU6

   Available Since

   July 6, 2016

   Availability

   Academic Institutions and Nonprofits only

   

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9. Lenti-sgFbxw7#1/Cre

   Plasmid

   #173635

   Purpose

   Expresses a Fbxw7-targeting gRNA and Cre-recombinase

   Depositor

   Charles Swanton

   Article

   Cai et al Cancer Discov. 2021 Feb 19. pii: 2159-82

   Insert

   gRNA targeting Fbxw7 (Fbxw7 Mouse)
   

   Use

   CRISPR, Cre/Lox, and Lentiviral

   Available Since

   May 18, 2022

   Availability

   Academic Institutions and Nonprofits only

   

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10. GCK gRNA (BRDN0001144982)

    Plasmid

    #77581

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human GCK

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    GCK (GCK Human)
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Promoter

    hU6

    Available Since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

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11. FGFR2 gRNA (BRDN0001148071)

    Plasmid

    #76182

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human FGFR2

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    FGFR2 (FGFR2 Human)
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Promoter

    hU6

    Available Since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

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12. pLKO.1-puro-shPSMD2

    Plasmid

    #125779

    Purpose

    constitutive expression of a short-hairpin RNA targeting human PSMD2 (RNAi positive control)

    Depositor

    Francisca Vazquez

    Article

    Chan et al Nature. 2019 Apr 10. pii: 10.1038/s41586

    Insert

    shPSMD2 (PSMD2 Human)
    

    Use

    RNAi

    Available Since

    June 4, 2019

    Availability

    Academic Institutions and Nonprofits only

    

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13. shERK2b-mlpx-neo

    Plasmid

    #65231

    Purpose

    encodes a shRNA against ERK2

    Depositor

    Gerardo Ferbeyre

    Article

    Deschenes-Simard et al Genes Dev. 2013 Apr 15;27(8):900-15. doi

    Insert

    shRNA against ERK2 (MAPK1 Human)
    

    Expression

    Mammalian

    Promoter

    PGK

    Available Since

    Aug. 12, 2015

    Availability

    Academic Institutions and Nonprofits only

    

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14. pDONR223-PLXNA4B

    Plasmid

    #23608

    Depositor

    William Hahn, David Root

    Article

    Johannessen et al Nature. 2010 Dec 16;468(7326):968-72. do

    Insert

    PLXNA4B (PLXNA4 Human)
    

    Use

    Gateway donor vector

    Available Since

    July 30, 2010

    Availability

    Academic Institutions and Nonprofits only

15. AURKB gRNA (BRDN0001149202)

    Plasmid

    #77617

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human AURKB

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    AURKB (AURKB Human)
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Promoter

    hU6

    Available Since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

16. FGFR1 gRNA (BRDN0001146517)

    Plasmid

    #76069

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human FGFR1

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    FGFR1 (FGFR1 Human)
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Promoter

    hU6

    Available Since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

17. pXPR_BRD051-sgCh2-2

    Plasmid

    #125775

    Purpose

    constitutive expression of a guide RNA targeting an intergenic region of human chromosome 2 (CRISPR cutting control) and S. pyogenes Cas9

    Depositor

    Francisca Vazquez

    Article

    Chan et al Nature. 2019 Apr 10. pii: 10.1038/s41586

    Insert

    sgCh2-2
    

    Use

    CRISPR

    Available Since

    June 4, 2019

    Availability

    Academic Institutions and Nonprofits only

    

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18. px330-Apob-3

    Plasmid

    #162550

    Purpose

    sgRNA targeting Apob

    Depositor

    Amaia Lujambio

    Article

    Molina-Sanchez et al Gastroenterology. 2020 Aug 16. pii: S001

    Insert

    sgRNA targeting Apob (Apob Mouse)
    

    Expression

    Mammalian

    Mutation

    None

    Promoter

    U6

    Available Since

    Feb. 16, 2021

    Availability

    Academic Institutions and Nonprofits only

    

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19. px330-Apob-4

    Plasmid

    #162551

    Purpose

    sgRNA targeting Apob

    Depositor

    Amaia Lujambio

    Article

    Molina-Sanchez et al Gastroenterology. 2020 Aug 16. pii: S001

    Insert

    sgRNA targeting Apob (Apob Mouse)
    

    Expression

    Mammalian

    Mutation

    None

    Promoter

    U6

    Available Since

    Feb. 16, 2021

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

20. HK2 gRNA (BRDN0001162236)

    Plasmid

    #76309

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human HK2

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    HK2 (HK2, HOOK2 Human)
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Promoter

    hU6

    Available Since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

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