We narrowed to 9,263 results for: CAG

1. pXPR_BRD003-sgWRN-EIJ

   Plasmid

   #125774

   Purpose

   constitutive expression of a guide RNA targeting an exon-intron junction of human WRN

   Depositor

   Francisca Vazquez

   Article

   Chan et al Nature. 2019 Apr 10. pii: 10.1038/s41586

   Insert

   sgWRN-EIJ (WRN Human)
   

   Use

   CRISPR

   Available Since

   June 11, 2019

   Availability

   Academic Institutions and Nonprofits only

   

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2. pENTR1A_mmFbxw7(res) (closed)

   Plasmid

   #160105

   Purpose

   Expresses murine Fbxw7 alpha with a T199 silent mutation in mammalian cells. The T199 silent mutation confers resistance to the 5'-TGAACATGGTACAAGGCCAG-3' sgRNA

   Depositor

   Rizwan Haq

   Article

   Gstalder et al Cancer Discov. 2020 May 5. pii: 2159-829

   Insert

   Fbxw7alpha (Fbxw7 Mouse)
   

   Use

   Gateway entry vector

   Expression

   Mammalian

   Available Since

   Oct. 13, 2020

   Availability

   Academic Institutions and Nonprofits only

   

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3. pXPR_BRD003 PSMB5 guide 2

   Plasmid

   #117074

   Purpose

   single guide RNA targeting PSMB5; guide 2

   Depositor

   William Hahn

   Article

   Hong et al Elife. 2019 Mar 12;8. pii: 44161. doi: 1

   Insert

   LMPX (PSMB5 Human)
   

   Use

   CRISPR

   Promoter

   hU6

   Available Since

   March 13, 2019

   Availability

   Academic Institutions and Nonprofits only

   

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4. HK1 gRNA (BRDN0001147564)

   Plasmid

   #77644

   Purpose

   3rd generation lentiviral gRNA plasmid targeting human HK1

   Depositor

   John Doench, David Root

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Insert

   HK1 (HK1, HOOK1 Human)
   

   Use

   CRISPR and Lentiviral

   Expression

   Mammalian

   Promoter

   hU6

   Available Since

   July 6, 2016

   Availability

   Academic Institutions and Nonprofits only

   

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5. AAV-U6-sgPlxnb2-KO-4-EF1a-LibVec

   Plasmid

   #239600

   Purpose

   expresses guide#4 to knock-out mouse Plxnb2, via CRISPR-Cas9

   Depositor

   Andreas Moor

   Article

   Borrelli et al Nature. 2024 Aug;632(8024):411-418. doi:

   Insert

   Plxnb2 (Plxnb2 Mouse)
   

   Use

   AAV

   Expression

   Mammalian

   Promoter

   hU6

   Available Since

   July 11, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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6. AAV-U6-sgPlxnb2-KO-2-EF1a-LibVec

   Plasmid

   #239598

   Purpose

   expresses guide#2 to knock-out mouse Plxnb2, via CRISPR-Cas9

   Depositor

   Andreas Moor

   Article

   Borrelli et al Nature. 2024 Aug;632(8024):411-418. doi:

   Insert

   Plxnb2 (Plxnb2 Mouse)
   

   Use

   AAV

   Expression

   Mammalian

   Promoter

   hU6

   Available Since

   July 11, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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7. pLV-RnSyt1-sgRNA2-dCas9-KRAB-TagBFP2 (identifier AAAA-0246)

   Plasmid

   #202555

   Purpose

   Synaptotagmin-1 sgRNA2 with TagBFP2

   Depositor

   Frederic Meunier

   Article

   Joensuu et al EMBO J. 2023 Jul 3;42(13):e112095. doi:

   Insert

   CRISPRi single guide RNA sequence against 5’-UTR of rat synaptotagmin-1 (Syt1) gene (insert 5’ - CACCAGTACTCGCGTGCCTCGCACCGG) (Syt1 Rat)
   

   Use

   CRISPR and Lentiviral

   Tags

   3xFlag (N-terminus of Cas9-KRAB), T2A-TagBFP2

   Available Since

   Dec. 12, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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8. pLV hU6-sgKRAS hUbC-dCas9-KRAB-T2a-GFP2

   Plasmid

   #184557

   Purpose

   Knockdown of murine KRAS gene by targeting the promoter region via CRISPRi system

   Depositor

   Sandeep Prabhu

   Article

   Qian et al Cell Rep. 2023 Jul 25;42(7):112794. doi:

   Insert

   Kirsten rat sarcoma virus (Kras Mouse)
   

   Use

   CRISPR, Lentiviral, and Mouse Targeting

   Tags

   Flag

   Expression

   Bacterial

   Available Since

   Oct. 15, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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9. RB1-TP53-LRG-GFP

   Plasmid

   #225876

   Purpose

   Guides targeting TP53 and RB1

   Depositor

   Janai Carr-Ascher

   Article

   Freeland et al Clin Cancer Res. 2024 Aug 23. doi: 10.11

   Insert

   RB1 and TP53 (TP53, RB1 Human)
   

   Use

   CRISPR and Lentiviral

   Promoter

   U6

   Available Since

   Oct. 15, 2024

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

10. Anti-CASK [K56A/50R-2b]

    Plasmid

    #222168

    Purpose

    Mammalian Expression Plasmid of anti-CASK (Human). Derived from hybridoma K56A/50.

    Depositor

    James Trimmer

    Article

    Mitchell et al Sci Rep. 2023 Sep 27;13(1):16200. doi: 1

    Insert

    Anti-CASK (Homo sapiens) recombinant mouse monoclonal antibody. (CASK Mouse)
    

    Expression

    Mammalian

    Promoter

    Dual CMV

    Available Since

    Sept. 5, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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11. TfR-SpyCatcher003(K31TAG)-sfGFP-MycTag-CTag

    Plasmid

    #210021

    Purpose

    Expression of transferrin receptor transmembrane domain and photocaged SpyCatcher003(K31HCK)-sfGFP on mammalian cell surface.

    Depositor

    Vesa Hytönen

    Article

    Rahikainen et al J Am Chem Soc. 2023 Nov 15;145(45):24459

    Insert

    Transferrin receptor transmembrane domain-SpyCatcher003(K31TAG)-superfolderGFP-MycTag-CTag (TFRC Human, Synthetic)
    

    Tags

    MycTag, CTag

    Expression

    Mammalian

    Mutation

    Transferrin receptor transmembrane domain with Y2…

    Promoter

    CMV promoter

    Available Since

    March 15, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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12. pKLV2.2-h7SKgRNA5(SMARCA4(43))-hU6gRNA5(AAVS1)-PGKpuroBFP-W

    Plasmid

    #200503

    Purpose

    Lentiviral vector expressing gRNA targeting human SMARCA4 and AAVS1

    Depositor

    Kosuke Yusa

    Article

    Aoki et al Blood. 2023 Nov 3:blood.2023020857. doi:

    Insert

    SMARCA4(43), AAVS1 (SMARCA4, AAVS1 Human)
    

    Use

    Lentiviral

    Available Since

    Jan. 17, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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13. pMXS-IRES-BLAST flag-CAD hCPS1 TL

    Plasmid

    #188150

    Purpose

    Expresses C-terminal flag-tagged human CAD hCPS1 TL in mammalian cells

    Depositor

    Richard Possemato

    Article

    Shin et al Nat Metab. 2023 Feb 6. doi: 10.1038/s422

    Insert

    CAD (CAD Human)
    

    Use

    Retroviral

    Tags

    Flag tag

    Expression

    Mammalian

    Mutation

    TCC -> AGT silent mutations at nt439-441 elimi…

    Available Since

    Feb. 6, 2023

    Availability

    Academic Institutions and Nonprofits only

14. pLD-puro-Cc-CR-PARK7WT-VA

    Plasmid

    #115187

    Purpose

    Lentiviral transduction and expression of CRISPR/Cas9-resistant PARK7WT into any mammalian cell (when using sgRNA seq agtacagtgtagccgtgatg)

    Depositor

    Mohan Babu

    Article

    Moutaoufik et al iScience. 2019 Sep 4;19:1114-1132. doi:

    Insert

    CR (CRISPR/Cas9-resistant)-PARK7WT (PARK7 Human)
    

    Use

    Lentiviral

    Tags

    Versatile affinity tag (2XStreptactin II-6XHis-3X…

    Mutation

    c.150G>A (silent when translated to protein, c…

    Promoter

    CMV

    Available Since

    March 26, 2021

    Availability

    Academic Institutions and Nonprofits only

    

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15. pLD-puro-Cc-CR-PARK7V51G-VA

    Plasmid

    #115188

    Purpose

    Lentiviral transduction and expression of CRISPR/Cas9-resistant PARK7V51G into any mammalian cell (when using sgRNA seq agtacagtgtagccgtgatg)

    Depositor

    Mohan Babu

    Article

    Moutaoufik et al iScience. 2019 Sep 4;19:1114-1132. doi:

    Insert

    CR (CRISPR/Cas9-resistant)-PARK7V51G (PARK7 Human)
    

    Use

    Lentiviral

    Tags

    Versatile affinity tag (2XStreptactin II-6XHis-3X…

    Mutation

    c.150G>A (silent when translated to protein, c…

    Promoter

    CMV

    Available Since

    March 26, 2021

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

16. pLD-puro-Cc-CR-PARK7C53A-VA

    Plasmid

    #115189

    Purpose

    Lentiviral transduction and expression of CRISPR/Cas9-resistant PARK7C53A into any mammalian cell (when using sgRNA seq agtacagtgtagccgtgatg)

    Depositor

    Mohan Babu

    Article

    Moutaoufik et al iScience. 2019 Sep 4;19:1114-1132. doi:

    Insert

    CR (CRISPR/Cas9-resistant)-PARK7C53A (PARK7 Human)
    

    Use

    Lentiviral

    Tags

    Versatile affinity tag (2XStreptactin II-6XHis-3X…

    Mutation

    c.150G>A (silent when translated to protein, c…

    Promoter

    CMV

    Available Since

    March 26, 2021

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

17. pLD-puro-Cc-CR-PARK7H126A-VA

    Plasmid

    #115190

    Purpose

    Lentiviral transduction and expression of CRISPR/Cas9-resistant PARK7H126A into any mammalian cell (when using sgRNA seq agtacagtgtagccgtgatg)

    Depositor

    Mohan Babu

    Article

    Moutaoufik et al iScience. 2019 Sep 4;19:1114-1132. doi:

    Insert

    CR (CRISPR/Cas9-resistant)-PARK7H126A (PARK7 Human)
    

    Use

    Lentiviral

    Tags

    Versatile affinity tag (2XStreptactin II-6XHis-3X…

    Mutation

    c.150G>A (silent when translated to protein, c…

    Promoter

    CMV

    Available Since

    March 26, 2021

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

18. pLD-puro-Cc-CR-PARK7E163K-VA

    Plasmid

    #115191

    Purpose

    Lentiviral transduction and expression of CRISPR/Cas9-resistant PARK7E163K into any mammalian cell (when using sgRNA seq agtacagtgtagccgtgatg)

    Depositor

    Mohan Babu

    Article

    Moutaoufik et al iScience. 2019 Sep 4;19:1114-1132. doi:

    Insert

    CR (CRISPR/Cas9-resistant)-PARK7E163K (PARK7 Human)
    

    Use

    Lentiviral

    Tags

    Versatile affinity tag (2XStreptactin II-6XHis-3X…

    Mutation

    c.150G>A (silent when translated to protein, c…

    Promoter

    CMV

    Available Since

    March 26, 2021

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

19. pLX304_zeo_mmFbxw7(res)

    Plasmid

    #160106

    Purpose

    Expresses murine Fbxw7 alpha with a T199 silent mutation in mammalian cells. The T199 silent mutation confers resistance to the 5'-TGAACATGGTACAAGGCCAG-3' sgRNA

    Depositor

    Rizwan Haq

    Article

    Gstalder et al Cancer Discov. 2020 May 5. pii: 2159-829

    Insert

    Fbxw7alpha (Fbxw7 Mouse)
    

    Use

    Lentiviral

    Expression

    Mammalian

    Available Since

    Oct. 13, 2020

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

20. pXPR_BRD003 UBE2C guide 1

    Plasmid

    #117068

    Purpose

    single guide RNA targeting UBE2C; guide 1

    Depositor

    William Hahn

    Article

    Hong et al Elife. 2019 Mar 12;8. pii: 44161. doi: 1

    Insert

    UBCH10 (UBE2C Human)
    

    Use

    CRISPR

    Promoter

    hU6

    Available Since

    March 13, 2019

    Availability

    Academic Institutions and Nonprofits only

    

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