We narrowed to 19,334 results for: Mut

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TRIPZ-CTID195-GSQ-SUMO1nc-PURO

Plasmid

#208035

Purpose

Enables inducible expression of C-terminal Split-TurboID-fused SUMO1nc, to perform SUMO-ID; nc = non-cleavable mutation; selection with puromycin

Depositor

Rosa Barrio, James Sutherland

Article

Barroso-Gomila et al Nat Commun. 2021 Nov 18;12(1):6671. doi:

Insert

SUMO1nc (SUMO1 Human)

Use

Lentiviral

Tags

Myc, C-terminal Split-TurboID

Mutation

Q94P Mutation near C-terminus suppresses cleavage…

Promoter

tetO/UBC

Available Since

Nov. 29, 2023

Availability

Academic Institutions and Nonprofits only

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PIG-MycT58A

Plasmid

#177648

Purpose

Expression of mouse Myc with T58A point mutation

Depositor

Trudy Oliver

Article

Mollaoglu et al Cancer Cell. 2017 Feb 13;31(2):270-285.

Insert

Myc-T58A (Myc Mouse)

Use

Retroviral

Tags

GFP and IRES

Expression

Mammalian

Mutation

T58A point mutation

Available Since

Feb. 2, 2022

Availability

Academic Institutions and Nonprofits only

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pDONR223_DECR1_WT_V5

Plasmid

#82989

Purpose

Gateway Donor vector containing DECR1, used as an over expression control for gene expression analysis. Part of the Target Accelerator Plasmid Collection.

Depositor

Jesse Boehm, Matthew Meyerson, David Root

Article

Berger et al Cancer Cell. 2016 Aug 8;30(2):214-28. do

Insert

DECR1 (DECR1 Human)

Use

Gateway entry vector

Promoter

None

Available Since

April 24, 2017

Availability

Academic Institutions and Nonprofits only

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pDONR223_ERBB2_p.S310F

Plasmid

#82854

Purpose

Gateway Donor vector containing ERBB2, part of the Target Accelerator Plasmid Collection.

Depositor

Jesse Boehm, Matthew Meyerson, David Root

Article

Berger et al Cancer Cell. 2016 Aug 8;30(2):214-28. do

Insert

ERBB2 (ERBB2 Human)

Use

Gateway entry vector

Mutation

S310F

Promoter

None

Available Since

April 24, 2017

Availability

Academic Institutions and Nonprofits only

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pHAGE-PTPN11-N308D

Plasmid

#116644

Purpose

Lentiviral expression of PTPN11 N308D

Depositor

Gordon Mills, Kenneth Scott

Article

Ng et al Cancer Cell. 2018 Mar 12;33(3):450-462.e

Insert

PTPN11 (PTPN11 Human)

Use

Lentiviral

Mutation

N308D

Available Since

March 14, 2019

Availability

Academic Institutions and Nonprofits only

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pMini-CMV-NLS-dead R-IscB_ADAR2dd-NES_T2A_mCherry (W98X)_U6-ωRNA

Plasmid

#246432

Purpose

All-in-one plasmid. Expresses R-IscB_ADAR2dd in mammalian cells for A-to-I RNA editing. Inactive mCherry included to assess A-to-I editing. Spacer included can direct mCherry fluorescence recovery.

Depositor

Ailong Ke

Article

Xu et al Cell. 2025 Aug 18:S0092-8674(25)00854-2.

Inserts

O.gue IscB with dead mutations (D60A, H269A) and delta-TID, fused to human ADAR2 deaminase domain
mCherry
ωRNA

Tags

HIV NES, SGGSSGGSSGSETPGTSESATPESSGGSSGGS linker …

Expression

Mammalian

Mutation

R-IscB: changed Aspartic Acid 60 to Alanine, chan…

Promoter

CMV and U6

Available Since

Nov. 13, 2025

Availability

Academic Institutions and Nonprofits only

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PGKp-GFP-YAP (S94A)

Plasmid

#174173

Purpose

Lentiviral vector to constitutively express TEAD-binding mutant YAP under control of the human PGK promoter.

Depositor

Rod Bremner

Article

Pearson et al Cancer Cell. 2021 Jul 13. pii: S1535-610

Insert

YAP (YAP1 Human)

Use

Lentiviral

Tags

3x FLAG tag

Expression

Mammalian

Mutation

Serine 94 mutated to Alanine

Promoter

PGK

Available Since

Aug. 19, 2021

Availability

Industry, Academic Institutions, and Nonprofits

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pdCas9-DNMT3A-PuroR (ANV)

Plasmid

#71684

Purpose

Expression of mutant human codon-optimized dCas9-DNMT3A fusion (inactive catalytic domain of DNMT3A) with T2A-PuroR; cloning backbone for sgRNA

Depositor

Vlatka Zoldos

Article

Vojta et al Nucleic Acids Res. 2016 Mar 11. pii: gkw

Insert

S. pyogenes dCas9 fused with the inactivated (E756A) catalytic domain of human DNMT3A (amino acids P602-V912) and T2A-PuroR (DNMT3A Synthetic, S. pyogenes, Human)

Use

CRISPR

Tags

3xFLAG, SV40 NLS, and T2A-PuroR

Expression

Mammalian

Mutation

D10A and H840A in S.pyogenes Cas9; E756A inactiva…

Promoter

CBh

Available Since

March 7, 2016

Availability

Academic Institutions and Nonprofits only

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pDONR223_EBNA1BP2_WT_V5

Plasmid

#82932

Purpose

Gateway Donor vector containing EBNA1BP2, used as an over expression control for gene expression analysis. Part of the Target Accelerator Plasmid Collection.

Depositor

Jesse Boehm, Matthew Meyerson, David Root

Article

Berger et al Cancer Cell. 2016 Aug 8;30(2):214-28. do

Insert

EBNA1BP2 (EBNA1BP2 Human)

Use

Gateway entry vector

Promoter

None

Available Since

April 24, 2017

Availability

Academic Institutions and Nonprofits only

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pDONR223_BMP4_WT_V5

Plasmid

#82937

Purpose

Gateway Donor vector containing BMP4 , used as an over expression control for gene expression analysis. Part of the Target Accelerator Plasmid Collection.

Depositor

Jesse Boehm, Matthew Meyerson, David Root

Article

Berger et al Cancer Cell. 2016 Aug 8;30(2):214-28. do

Insert

BMP4 (BMP4 Human)

Use

Gateway entry vector

Mutation

V152A

Promoter

None

Available Since

April 24, 2017

Availability

Academic Institutions and Nonprofits only

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pDONR223_DNTTIP2_WT_V5

Plasmid

#82939

Purpose

Gateway Donor vector containing DNTTIP2, used as an over expression control for gene expression analysis. Part of the Target Accelerator Plasmid Collection.

Depositor

Jesse Boehm, Matthew Meyerson, David Root

Article

Berger et al Cancer Cell. 2016 Aug 8;30(2):214-28. do

Insert

DNTTIP2 (DNTTIP2 Human)

Use

Gateway entry vector

Mutation

E309D

Promoter

None

Available Since

April 24, 2017

Availability

Academic Institutions and Nonprofits only

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pHAGE-PTEN-R130G

Plasmid

#116630

Purpose

Lentiviral expression of PTEN R130G

Depositor

Gordon Mills, Kenneth Scott

Article

Ng et al Cancer Cell. 2018 Mar 12;33(3):450-462.e

Insert

PTEN (PTEN Human)

Use

Lentiviral

Mutation

R130G

Available Since

March 14, 2019

Availability

Academic Institutions and Nonprofits only

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pDONR223_ID2_WT_V5

Plasmid

#82960

Purpose

Gateway Donor vector containing ID2, used as an over expression control for gene expression analysis. Part of the Target Accelerator Plasmid Collection.

Depositor

Jesse Boehm, Matthew Meyerson, David Root

Article

Berger et al Cancer Cell. 2016 Aug 8;30(2):214-28. do

Insert

ID2 (ID2 Human)

Use

Gateway entry vector

Promoter

None

Available Since

April 24, 2017

Availability

Academic Institutions and Nonprofits only

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pHoY110_pAC8_hsDCAF5_FL

Plasmid

#249183

Purpose

Express DCAF5(full length) in Insect cells

Depositor

Eric Fischer

Article

Radko-Juettner et al Nature. 2024 Apr;628(8007):442-449. doi:

Insert

DCAF5 full length (DCAF5 Human)

Tags

Strep_BirA_short-linker-TEV

Expression

Insect

Mutation

N/A

Available Since

Dec. 1, 2025

Availability

Academic Institutions and Nonprofits only

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JDW 762 (pCS2-EGFP-hsKRAS4B-G12V)

Plasmid

#156407

Purpose

pCS2 CMV expression vector driving EGFP fused human KRAS4B-G12V

Depositor

Joshua Wythe

Article

Fish et al Circ Res. 2020 Jun 17. doi: 10.1161/CIRC

Insert

human mutant KRAS4B-G12V (KRAS Human)

Tags

EGFP

Expression

Mammalian

Mutation

mutant KRAS4B-G12V

Promoter

CMV

Available Since

Aug. 18, 2020

Availability

Academic Institutions and Nonprofits only

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pHAGE-MAPK1

Plasmid

#116760

Purpose

Lentiviral expression of MAPK1

Depositor

Gordon Mills, Kenneth Scott

Article

Ng et al Cancer Cell. 2018 Mar 12;33(3):450-462.e

Insert

MAPK1 (MAPK1 Human)

Use

Lentiviral

Mutation

WT

Available Since

March 14, 2019

Availability

Academic Institutions and Nonprofits only

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pHAGE-ERBB2-S310F

Plasmid

#116349

Purpose

Lentiviral expression of ERBB2 S310F

Depositor

Gordon Mills, Kenneth Scott

Article

Ng et al Cancer Cell. 2018 Mar 12;33(3):450-462.e

Insert

ERBB2 (ERBB2 Human)

Use

Lentiviral

Mutation

S310F

Available Since

March 14, 2019

Availability

Academic Institutions and Nonprofits only

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pYY166 pcDNA3.4-His-MBP-hAID

Plasmid

#231942

Purpose

Expression of His-MBP-AID fusion protein in mammalian cells

Depositor

Fei-Long Meng

Article

Wang et al Cell. 2023 May 11;186(10):2193-2207.e19.

Insert

AID (AICDA Human)

Tags

His-MBP

Expression

Mammalian

Promoter

CMV

Available Since

March 21, 2025

Availability

Academic Institutions and Nonprofits only

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pLenti-Ef1a-mClover-W377A/W428A YTHDC1-T2A-BSD-siRNA-Resistant

Plasmid

#177130

Purpose

Generate lentivirus to introduce mClover tagged m6A binding null mutant W377A/W428A YTHDC1

Depositor

Wenbo Li

Article

Lee et al Mol Cell. 2021 Aug 19;81(16):3368-3385.e

Insert

YTHDC1 (YTHDC1 Human)

Use

Lentiviral

Tags

mClover3

Mutation

W428A/W377A (m6A binding defects), and siRNA resi…

Promoter

Ef1a

Available Since

July 7, 2022

Availability

Academic Institutions and Nonprofits only

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pcDNA5-FRT/T0-Flag-CIP2A

Plasmid

#222623

Purpose

mammalian expression vector of Flag-tagged CIP2A

Depositor

Daniel Durocher

Article

Adam et al Nat Cancer. 2021 Dec;2(12):1357-1371. do

Insert

CIP2A (CIP2A Human)

Tags

Flag

Expression

Mammalian

Promoter

CMV

Available Since

July 18, 2024

Availability

Industry, Academic Institutions, and Nonprofits

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