We narrowed to 88,229 results for: Mal;

1. SAM-DNMT3A empty

   Plasmid

   #213164

   Purpose

   Empty vector (no sgRNA) for induction of global DNA methylation.

   Depositor

   Sefi Rosenbluh

   Article

   Hosseinpour et al Nat Commun. 2024 Dec 1;15(1):10449. doi:

   Type

   Empty backbone

   Use

   CRISPR, Lentiviral, and Synthetic Biology

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   E1Fa and U6

   Available Since

   Dec. 2, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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2. SAM-DNMT3A+sgGFP

   Plasmid

   #213165

   Purpose

   Vector with sgGFP for induction of global DNA methylation.

   Depositor

   Sefi Rosenbluh

   Article

   Hosseinpour et al Nat Commun. 2024 Dec 1;15(1):10449. doi:

   Insert

   sgGFP
   

   Use

   CRISPR, Lentiviral, and Synthetic Biology

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   E1Fa and U6 and PGK

   Available Since

   Dec. 2, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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3. SAM-DNMT3A+sgAAVS1_145

   Plasmid

   #213166

   Purpose

   Vector with sgAAVS1 for induction of global DNA methylation.

   Depositor

   Sefi Rosenbluh

   Article

   Hosseinpour et al Nat Commun. 2024 Dec 1;15(1):10449. doi:

   Insert

   sgAAVS1_145
   

   Use

   CRISPR, Lentiviral, and Synthetic Biology

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   E1Fa and U6

   Available Since

   Dec. 2, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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4. SAM-DNMT3A+sgAAVS1_118

   Plasmid

   #213167

   Purpose

   Vector with sgAAVS1 for induction of global DNA methylation.

   Depositor

   Sefi Rosenbluh

   Article

   Hosseinpour et al Nat Commun. 2024 Dec 1;15(1):10449. doi:

   Insert

   sgAAVS1_118
   

   Use

   CRISPR, Lentiviral, and Synthetic Biology

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   E1Fa and U6

   Available Since

   Dec. 2, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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5. SAM-DNMT3A-inactiveEmpty

   Plasmid

   #213168

   Purpose

   Empty Vector (no sgRNA) used as a negative control (inactive DNMT3A) for induction of global DNA methylation.

   Depositor

   Sefi Rosenbluh

   Article

   Hosseinpour et al Nat Commun. 2024 Dec 1;15(1):10449. doi:

   Type

   Empty backbone

   Use

   CRISPR, Lentiviral, and Synthetic Biology

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   E1Fa and U6

   Available Since

   Dec. 2, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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6. pUC-hU6-crBACH1-array_EF1a-BFP

   Plasmid

   #224787

   Purpose

   BACH1 targeting crRNA array for RfxCas13d expressed from multiple hU6 promoter and reporter BFP protein expressed from EF1a promoter

   Depositor

   Gabor Balazsi

   Article

   Wan et al ACS Synth Biol. 2024 Oct 18;13(10):3212-

   Insert

   crBACH1-1, crBACH1-2, crBACH1-3,
   

   Use

   CRISPR and Synthetic Biology

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   hU6 and hU6-2xTetO

   Available Since

   Oct. 31, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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7. LPUtopia-7_CoV-2

   Plasmid

   #224782

   Purpose

   Landing Pad donor vector containing partial RdRp and N gene sequences from SARS-CoV-2 for fluorescent reporter assay

   Depositor

   Gabor Balazsi

   Article

   Wan et al ACS Synth Biol. 2024 Oct 18;13(10):3212-

   Insert

   partial RdRp and N gene (N, ORF1ab SARS-CoV-2)
   

   Use

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   Available Since

   Oct. 31, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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8. pTRE3G-marmoset cGASdeltaN-HA

   Plasmid

   #186863

   Purpose

   Doxycycline-dependent expression of marmoset cGAS gene in mammalian cells by retroviral transduction

   Depositor

   Jonathan Kagan

   Article

   Mosallanejad et al Sci Immunol. 2023 Jan 20;8(79):eabp9765.

   Insert

   Marmoset cGAS truncation mutant (160-547 a.a.) with C-terminal HA tag
   

   Use

   Retroviral

   Tags

   HA

   Expression

   Mutation

   N-terminal truncation

   Promoter

   TRE3G

   Available Since

   Oct. 23, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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9. pTRE3G-WHG cGASdeltaN-HA

   Plasmid

   #186868

   Purpose

   Doxycycline-dependent expression of white-handed gibbon cGAS gene in mammalian cells by retroviral transduction

   Depositor

   Jonathan Kagan

   Article

   Mosallanejad et al Sci Immunol. 2023 Jan 20;8(79):eabp9765.

   Insert

   White-handed gibbon cGAS truncation mutant (193-557 a.a.) with C-terminal HA tag
   

   Use

   Retroviral

   Tags

   HA

   Expression

   Mutation

   N-terminal truncation

   Promoter

   TRE3G

   Available Since

   Oct. 23, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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10. pU6-hL1-5'_3.3kb plasmid

    Plasmid

    #226006

    Purpose

    Plasmid used to generate DNA-FISH probe targeting at human L1HS

    Depositor

    Miguel Ramalho-Santos

    Article

    Zhang et al Dev Cell. 2024 Oct 14:S1534-5807(24)0057

    Insert

    Human L1 element 3.3kb sequences at the 5' end
    

    Use

    Synthetic Biology

    Tags

    Expression

    Mutation

    Promoter

    Available Since

    Oct. 16, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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11. pBSII-PGK-FLPo-IRES-Puro

    Plasmid

    #205989

    Purpose

    Expresses Flp recombinase and puromycin resistance

    Depositor

    Sharon Torigoe

    Article

    Waite et al PLoS One. 2024 Sep 30;19(9):e0311120. do

    Inserts

    PGK promoter
    FLPo (flp )
    IRES-PuroR cassette
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    PGK promoter

    Available Since

    Oct. 1, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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12. pWZL-hygro-FAKS722A

    Plasmid

    #216545

    Purpose

    This retroviral plasmid expresses a mutated cDNA (dominant negative: S722A) of human PTK2

    Depositor

    Georgia Konstantinidou

    Article

    Pozzato et al EMBO Mol Med. 2024 Sep 13. doi: 10.1038/

    Insert

    PTK2 (S722A) (PTK2 Human)
    

    Use

    Retroviral

    Tags

    No

    Expression

    Mammalian

    Mutation

    FAK dominant negative mutation S722A

    Promoter

    Available Since

    Sept. 16, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

13. pWZL-hygro-FAKY861F

    Plasmid

    #216546

    Purpose

    This retroviral plasmid expresses a mutated cDNA (dominant negative: Y861F) of human PTK2

    Depositor

    Georgia Konstantinidou

    Article

    Pozzato et al EMBO Mol Med. 2024 Sep 13. doi: 10.1038/

    Insert

    PTK2 (Y861F) (PTK2 Human)
    

    Use

    Retroviral

    Tags

    No

    Expression

    Mammalian

    Mutation

    FAK dominant negative mutation Y861F

    Promoter

    Available Since

    Sept. 16, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

14. pWZL-hygro-FAKY397F

    Plasmid

    #216677

    Purpose

    This retroviral plasmid expresses a mutated cDNA (dominant negative: Y397F) of human PTK2

    Depositor

    Georgia Konstantinidou

    Article

    Pozzato et al EMBO Mol Med. 2024 Sep 13. doi: 10.1038/

    Insert

    PTK2 (Y397F) (PTK2 Human)
    

    Use

    Retroviral

    Tags

    No

    Expression

    Mammalian

    Mutation

    FAK dominant negative mutation Y397F

    Promoter

    Available Since

    Sept. 16, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

15. pWZL-hygro-FAKS732A

    Plasmid

    #216541

    Purpose

    This retroviral plasmid expresses a mutated cDNA (dominant negative: S732A) of human PTK2

    Depositor

    Georgia Konstantinidou

    Article

    Pozzato et al EMBO Mol Med. 2024 Sep 13. doi: 10.1038/

    Insert

    PTK2 (S732A) (PTK2 Human)
    

    Use

    Retroviral

    Tags

    No

    Expression

    Mammalian

    Mutation

    FAK dominant negative mutation S732A

    Promoter

    Available Since

    Sept. 16, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

16. pWZL-hygro-FAKS910A

    Plasmid

    #216542

    Purpose

    This retroviral plasmid expresses a mutated cDNA (dominant negative: S910A) of human PTK2

    Depositor

    Georgia Konstantinidou

    Article

    Pozzato et al EMBO Mol Med. 2024 Sep 13. doi: 10.1038/

    Insert

    PTK2 (S910A) (PTK2 Human)
    

    Use

    Retroviral

    Tags

    No

    Expression

    Mammalian

    Mutation

    FAK dominant negative mutation S910A

    Promoter

    Available Since

    Sept. 16, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

17. pET21b-Cdc42/13C-FKBP-MBP

    Plasmid

    #214291

    Purpose

    Express split-Cdc42 fragment fused with FKBP and MBP

    Depositor

    Cliff Stains

    Article

    He et al Angew Chem Int Ed Engl. 2024 Jul 26:e202

    Insert

    Split-Cdc42 fragment fused with FKBP (CDC42 Human)
    

    Use

    Tags

    Maltose-binding protein (MBP)

    Expression

    Bacterial

    Mutation

    Cdc42-Q61L

    Promoter

    T7

    Available Since

    July 29, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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18. pET21b-Rac1/13C-FKBP-MBP

    Plasmid

    #214295

    Purpose

    Express split-Rac1 fragment fused with FKBP and MBP

    Depositor

    Cliff Stains

    Article

    He et al Angew Chem Int Ed Engl. 2024 Jul 26:e202

    Insert

    Split-Rac1 fragment fused with FKBP (RAC1 Human)
    

    Use

    Tags

    Maltose-binding protein (MBP)

    Expression

    Bacterial

    Mutation

    Rac1-Q61L

    Promoter

    T7

    Available Since

    July 29, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

19. pET21b-RhoA/13C-FKBP-MBP

    Plasmid

    #214299

    Purpose

    Express split-RhoA fragment fused with FKBP and MBP

    Depositor

    Cliff Stains

    Article

    He et al Angew Chem Int Ed Engl. 2024 Jul 26:e202

    Insert

    Split-RhoA fragment fused with FKBP (RHOA Human)
    

    Use

    Tags

    Maltose-binding protein (MBP)

    Expression

    Bacterial

    Mutation

    RhoA-Q63L

    Promoter

    T7

    Available Since

    July 29, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

20. pTFG011_Spike_Parental_D614G_3xFlag

    Plasmid

    #191571

    Purpose

    SARS-CoV-2 Spike protein under CMV with D614G, C-term 19 amino acid truncation, and 3x FLAG. For expression and pseudotyping lentiviral particles.

    Depositor

    Joshua Leonard

    Article

    Gunnels et al Small. 2022 May;18(19):e2200125. doi: 10

    Insert

    SARS-CoV-2 Spike Protein (S Synthetic)
    

    Use

    Tags

    3x FLAG

    Expression

    Mammalian

    Mutation

    D614G mutation. Last 19 amino acids truncated.

    Promoter

    CMV

    Available Since

    July 25, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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