165,567 results

1. pMini-CMV-NLS-dead R-IscB-NLS_T2A_EGFP (Y67X)_LNMA intron

   Plasmid

   #246435

   Purpose

   Expresses inactive EGFP (Y67X) in mammalian cells for trans-splicing assessments. LMNA intron is inserted into EGFP CDS.

   Depositor

   Ailong Ke

   Article

   Xu et al Cell. 2025 Aug 18:S0092-8674(25)00854-2.

   Inserts

   O.gue IscB with dead mutations (D60A, H269A) and delta-TID
   EGFP
   

   Tags

   SV40 NLS, Thosea asigna virus 2A peptide, and nuc…

   Expression

   Mammalian

   Mutation

   changed Aspartic Acid 60 to Alanine, changed Hist…

   Promoter

   CMV

   Available Since

   Oct. 27, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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2. pNP3440 [pNP2922 - ISCro4 bRNA (TBL2, WT + DBL1, WT) + ISCro4 Recombinase (WT)]

   Plasmid

   #247263

   Purpose

   Express ISCro4 recombinase and bridge RNA

   Depositor

   Patrick Hsu

   Article

   Perry et al Science. 2025 Sep 25:eadz0276. doi: 10.1

   Insert

   pNP2922 - ISCro4 bRNA1-179 (WT, TBL2 + DBL1)
   

   Expression

   Mammalian

   Available Since

   Oct. 23, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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3. pNP3414 [pNP2922 - ISCro4 Enhanced TBL (TBL4, WT) + ISCro4 Recombinase (WT)]

   Plasmid

   #247261

   Purpose

   Express ISCro4 recombinase and bridge RNA

   Depositor

   Patrick Hsu

   Article

   Perry et al Science. 2025 Sep 25:eadz0276. doi: 10.1

   Insert

   pNP2922 - ISCro4 bRNA1-100 C60U, A61G, U73C, dU86, A87G, dU88 (TBL4)
   

   Expression

   Mammalian

   Mutation

   C60U, A61G, U73C, dU86, A87G, dU88

   Available Since

   Oct. 23, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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4. pNP2389 [pNP2314 - ISCro4 Donor + ISCro4 Target-RTG-Matched]

   Plasmid

   #247251

   Purpose

   Measure ISCro4 activity via luciferase expression

   Depositor

   Patrick Hsu

   Article

   Perry et al Science. 2025 Sep 25:eadz0276. doi: 10.1

   Insert

   pNP2314 - ISCro4_Donor, ISCro4_Target_RTG-Matched
   

   Expression

   Mammalian

   Available Since

   Oct. 23, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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5. FEOX-PBCS-TBF2- MC2

   Plasmid

   #234406

   Purpose

   Tool for genetically encoded fluorescent biosensor of cellular iron microenvironment

   Depositor

   Carolyn Sangokoya

   Article

   Sangokoya et al Sci Rep. 2025 Oct 21;15(1):36596. doi: 1

   Inserts

   FEOX1 CONTROL
   FEOX
   

   Use

   Synthetic Biology

   Tags

   mTagBFP2

   Expression

   Mammalian

   Promoter

   EF1-alpha and hpgk

   Available Since

   Oct. 22, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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6. pLPC-Myc-BirA

   Plasmid

   #234039

   Purpose

   Expresses Myc-His-BirA(R118G)

   Depositor

   Roderick O'Sullivan

   Article

   Garcia-Exposito et al Cell Rep. 2016 Nov 8;17(7):1858-1871. do

   Insert

   BirA
   

   Use

   Retroviral

   Tags

   Myc-6xHis

   Expression

   Mammalian

   Mutation

   R118G

   Available Since

   Aug. 15, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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7. pLPC-Myc-BirA-TRF1

   Plasmid

   #234040

   Purpose

   Expresses Myc-His-BirA(R118G)-TRF1

   Depositor

   Roderick O'Sullivan

   Article

   Garcia-Exposito et al Cell Rep. 2016 Nov 8;17(7):1858-1871. do

   Insert

   TRF1 (TERF1 Human)
   

   Use

   Retroviral

   Tags

   Myc-6xHis-BirA(R118G)

   Expression

   Mammalian

   Available Since

   Aug. 15, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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8. pcDNA5 HIS-Ub-K48R

   Plasmid

   #221368

   Purpose

   Expresses 6xHIS-tagged Ubiquitin containing K48R mutation in mammalian cells

   Depositor

   Aga Gambus

   Article

   Jones et al iScience. 2024 Jun 12;27(7):110260. doi:

   Insert

   Ubiquitin
   

   Tags

   6xHIS

   Expression

   Mammalian

   Mutation

   Changed Lysine 48 to Arginine

   Promoter

   CMV

   Available Since

   Aug. 14, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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9. pcDNA3.1(+)-Flag-SOD1-G93A

   Plasmid

   #235662

   Purpose

   Express human SOD1-G93A in mammalian cells

   Depositor

   Chen Seng Ng

   Article

   Hiew et al Commun Biol. 2025 Mar 2;8(1):347. doi: 1

   Insert

   SOD1-G93A (SOD1 Human)
   

   Tags

   Flag-tag at N-terminal

   Expression

   Mammalian

   Mutation

   changed Glycine 93 to alanine

   Promoter

   CMV promoter

   Available Since

   July 28, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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10. pPBbsr2-RaichuEV-Rac1HRasCT

    Plasmid

    #214818

    Purpose

    Encoding a Förster resonance energy transfer (FRET) biosensor for Rac1 activity with cyan and yellow fluorescent protein.

    Depositor

    Michiyuki Matsuda

    Article

    Jikko et al J Cell Sci. 2025 Jul 16:jcs.263779. doi:

    Insert

    RaichuEV-Rac1HRasCT
    

    Tags

    HRasCAAX

    Expression

    Mammalian

    Promoter

    CAG promoter

    Available Since

    July 22, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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