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TRCN0000279952

Plasmid

#78155

Purpose

shCDK4 targeting 3UTR

Depositor

William Hahn

Article

Hong et al Nat Commun. 2016 Jun 22;7:11987. doi: 10

Insert

CDK4 (CDK4 Human)

Use

Lentiviral and RNAi

Promoter

hU6 and hU6

Available Since

June 22, 2016

Availability

Academic Institutions and Nonprofits only
TRCN0000279953

Plasmid

#78154

Purpose

shCDK4 targeting CDS

Depositor

William Hahn

Article

Hong et al Nat Commun. 2016 Jun 22;7:11987. doi: 10

Insert

CDK4 (CDK4 Human)

Use

Lentiviral and RNAi

Promoter

hU6 and hU6

Available Since

June 22, 2016

Availability

Academic Institutions and Nonprofits only
pCS2-mkgDUX4mal*leu*

Plasmid

#21173

Depositor

Stephen Tapscott

Article

Snider et al Hum Mol Genet. 2009 Jul 1;18(13):2414-30

Insert

DUX4 (DUX4 Human)

Expression

Bacterial and Mammalian

Mutation

First point mutation at nucleotide 5114 (numberin…

Available Since

Aug. 28, 2009

Availability

Academic Institutions and Nonprofits only
pMiR-RECK-3'UTR-miR-7-mut

Plasmid

#53692

Purpose

Luciferase reporter assay for RECK 3'UTR that has point mutations on miR-7 binding site

Depositor

Edward Chan

Article

Jung et al J Biol Chem. 2012 Aug 24;287(35):29261-7

Insert

RECK-3'UTR (RECK Human)

Use

Luciferase

Mutation

nucleotide position 171-174 are mutated to GAAG

Available Since

July 22, 2014

Availability

Academic Institutions and Nonprofits only
lentiCRISPR v2-sgFDX1-2

Plasmid

#251680

Purpose

gRNA to knock out FDX1 in mammalian cells

Depositor

Boyi Gan

Article

Lei et al Cancer Cell. 2025 Jun 9;43(6):1076-1092.

Insert

FDX1 ferredoxin 1 (FDX1 Human)

Use

CRISPR and Lentiviral

Available Since

Feb. 18, 2026

Availability

Academic Institutions and Nonprofits only

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lentiCRISPR v2-sgFDX1-1

Plasmid

#251679

Purpose

gRNA to knock out FDX1 in mammalian cells

Depositor

Boyi Gan

Article

Lei et al Cancer Cell. 2025 Jun 9;43(6):1076-1092.

Insert

FDX1 ferredoxin 1 (FDX1 Human)

Use

CRISPR and Lentiviral

Available Since

Feb. 3, 2026

Availability

Academic Institutions and Nonprofits only

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pLentiGuide-Puro-FE

Plasmid

#248560

Purpose

A CRISPR-based technology to study chromosome-specific aneuploidy by targeting human centromeres

Depositor

Teresa Davoli

Article

Bosco et al Cell. 2023 Apr 27;186(9):1985-2001.e19.

Type

Empty backbone

Use

CRISPR

Expression

Mammalian

Available Since

Feb. 3, 2026

Availability

Academic Institutions and Nonprofits only

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pLenti-gRNA-NC3

Plasmid

#248559

Purpose

A CRISPR-based technology to study chromosome-specific aneuploidy by targeting human centromeres

Depositor

Teresa Davoli

Article

Bosco et al Cell. 2023 Apr 27;186(9):1985-2001.e19.

Insert

gRNA-NC3 TD#417

Use

CRISPR

Expression

Mammalian

Promoter

U6

Available Since

Jan. 28, 2026

Availability

Academic Institutions and Nonprofits only

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pCS2_hsPum2_hsAdar2

Plasmid

#250539

Purpose

In vitro transcription (SP6 promotor) or mammalian expression (CMV promotor) of human Pum2 fused to the catalytic domain of human Adar2

Depositor

Daniel Cifuentes

Article

Kretov et al Mol Cell. 2026 Feb 6:S1097-2765(26)00023

Insert

hsPum2_hsAdar2 (ADARB1, PUM1 Human)

Use

Synthetic Biology

Available Since

Jan. 26, 2026

Availability

Academic Institutions and Nonprofits only

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pDonor MAFA-P2A-tdTomato

Plasmid

#246654

Purpose

Donor plasmid for Crispr/Cas9 gene editing of the human MAFA locus

Depositor

Joriene de Nooij

Article

Malka-Gibor et al Stem Cell Reports. 2026 Jan 2:102753. do

Insert

P2A-tdTomato flanked by MAFA homology regions (MAFA Synthetic, Human)

Use

CRISPR

Expression

Mammalian

Available Since

Jan. 26, 2026

Availability

Academic Institutions and Nonprofits only

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pDonor AVIL-P2A-iCre

Plasmid

#246652

Purpose

Donor plasmid for Crispr/Cas9 gene editing of the human AVIL locus

Depositor

Joriene de Nooij

Article

Malka-Gibor et al Stem Cell Reports. 2026 Jan 2:102753. do

Insert

P2A-iCre flanked by AVIL homology regions (AVIL Synthetic, Human)

Use

CRISPR

Expression

Mammalian

Available Since

Jan. 7, 2026

Availability

Academic Institutions and Nonprofits only

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pLenti-gRNA2-4

Plasmid

#248525

Purpose

A CRISPR-based technology to study chromosome-specific aneuploidy by targeting human centromeres

Depositor

Teresa Davoli

Article

Bosco et al Cell. 2023 Apr 27;186(9):1985-2001.e19.

Insert

gRNA2-4

Use

CRISPR

Expression

Mammalian

Promoter

U6

Available Since

Jan. 5, 2026

Availability

Academic Institutions and Nonprofits only

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pLenti-gRNAY-4

Plasmid

#248556

Purpose

A CRISPR-based technology to study chromosome-specific aneuploidy by targeting human centromeres

Depositor

Teresa Davoli

Article

Bosco et al Cell. 2023 Apr 27;186(9):1985-2001.e19.

Insert

gRNAY-4

Use

CRISPR

Expression

Mammalian

Promoter

U6

Available Since

Dec. 18, 2025

Availability

Academic Institutions and Nonprofits only

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pLenti-gRNA22-3

Plasmid

#248550

Purpose

A CRISPR-based technology to study chromosome-specific aneuploidy by targeting human centromeres

Depositor

Teresa Davoli

Article

Bosco et al Cell. 2023 Apr 27;186(9):1985-2001.e19.

Insert

gRNA22-3

Use

CRISPR

Expression

Mammalian

Promoter

U6

Available Since

Dec. 18, 2025

Availability

Academic Institutions and Nonprofits only

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pLenti-gRNA14-3

Plasmid

#248542

Purpose

A CRISPR-based technology to study chromosome-specific aneuploidy by targeting human centromeres

Depositor

Teresa Davoli

Article

Bosco et al Cell. 2023 Apr 27;186(9):1985-2001.e19.

Insert

gRNA14-3

Use

CRISPR

Expression

Mammalian

Promoter

U6

Available Since

Dec. 18, 2025

Availability

Academic Institutions and Nonprofits only

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pLenti-gRNA10-1

Plasmid

#248535

Purpose

A CRISPR-based technology to study chromosome-specific aneuploidy by targeting human centromeres

Depositor

Teresa Davoli

Article

Bosco et al Cell. 2023 Apr 27;186(9):1985-2001.e19.

Insert

gRNA10-1

Use

CRISPR

Expression

Mammalian

Promoter

U6

Available Since

Dec. 18, 2025

Availability

Academic Institutions and Nonprofits only

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pLenti-gRNA4-3

Plasmid

#248527

Purpose

A CRISPR-based technology to study chromosome-specific aneuploidy by targeting human centromeres

Depositor

Teresa Davoli

Article

Bosco et al Cell. 2023 Apr 27;186(9):1985-2001.e19.

Insert

gRNA4-3

Use

CRISPR

Expression

Mammalian

Promoter

U6

Available Since

Dec. 18, 2025

Availability

Academic Institutions and Nonprofits only

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pcDNA5-ZNF207-3xFLAG

Plasmid

#231929

Purpose

Vector for generating Flp-In cell lines allowing dox-inducible mammalian expression of ZNF207-3xFLAG

Depositor

Thomas Gonatopoulos-Pournatzis

Article

Behera et al Mol Cell. 2026 Jan 8;86(1):41-59.e15. do

Insert

ZNF207 (ZNF207 Human)

Tags

FLAG

Expression

Mammalian

Promoter

CMV/TO inducible promoter

Available Since

Dec. 12, 2025

Availability

Academic Institutions and Nonprofits only

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pcDNA5-ZNF207_∆GLEBS_3xFLAG

Plasmid

#231935

Purpose

Vector for generating Flp-In cell lines allowing dox-inducible mammalian expression of ZNF207_∆GLEBS_3xFLAG

Depositor

Thomas Gonatopoulos-Pournatzis

Article

Behera et al Mol Cell. 2026 Jan 8;86(1):41-59.e15. do

Insert

ZNF207 (ZNF207 Human)

Tags

FLAG

Expression

Mammalian

Mutation

?GLEBS

Promoter

CMV/TO inducible promoter

Available Since

Dec. 12, 2025

Availability

Academic Institutions and Nonprofits only

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pcDNA5-ZNF207-miniTurbo

Plasmid

#231938

Purpose

Vector for generating Flp-In cell lines allowing dox-inducible mammalian expression of ZNF207-miniTurbo

Depositor

Thomas Gonatopoulos-Pournatzis

Article

Behera et al Mol Cell. 2026 Jan 8;86(1):41-59.e15. do

Insert

ZNF207 (ZNF207 Human)

Tags

FLAG-miniTurbo

Expression

Mammalian

Promoter

CMV/TO inducible promoter

Available Since

Dec. 12, 2025

Availability

Academic Institutions and Nonprofits only

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