We narrowed to 232 results for: SYN1

1. pOTTC1761 - pAAV SYN1 DIO HA-hM3D(Gq)

   Plasmid

   #125147

   Purpose

   An adeno-associated viral vector expressing Cre-dependent HA-tagged inhibitory DREADD (hM3D(Gq)) from a synapsin promoter

   Depositor

   Christopher Richie

   Insert

   HA-tagged hM3D(Gq) (CHRM3 Human)
   

   Use

   AAV and Cre/Lox

   Tags

   HA

   Expression

   Mammalian

   Mutation

   Promoter

   SYN1

   Available since

   May 13, 2019

   Availability

   Academic Institutions and Nonprofits only

   

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2. pAAV-Syn1-GRAB-HTR6-cilia

   Plasmid

   #189615

   Purpose

   Expresses cilia-targeted serotonin sensor based on HTR6 receptor and cpEGFP, driven by SYN promoter

   Depositor

   David Clapham

   Article

   Sheu et al Cell. 2022 Sep 1;185(18):3390-3407.e18.

   Insert

   HTR6_GRAB
   

   Use

   AAV

   Tags

   Expression

   Mutation

   Promoter

   Syn1

   Available since

   March 15, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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3. pAAV-Syn1-DIO-VGLUT2:miniSOG

   Plasmid

   #214200

   Purpose

   For Cre-dependent expression of VGLUT2:miniSOG (miniSOG is lumen-facing and HA-tagged)

   Depositor

   Thomas Hnasko

   Article

   Steinkellner et al ACS Chem Neurosci. 2021 Feb 17;12(4):626

   Insert

   Slc17a6 tagged with miniSOG and hemagglutinin
   

   Use

   AAV and Cre/Lox

   Tags

   miniSOG (tagged with HA) is fused to the first in…

   Expression

   Mammalian

   Mutation

   Promoter

   Available since

   April 16, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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4. pAAV2-hSyn1-NES-ChemoG-CaM

   Plasmid

   #193817

   Purpose

   Expression of ChemoG-CaM in primary neurons

   Depositor

   Julien Hiblot

   Article

   Hellweg et al Nat Chem Biol. 2023 Jun 8. doi: 10.1038/

   Insert

   ChemoG-CaM
   

   Use

   AAV

   Tags

   Expression

   Mutation

   EGFP:A206K; HT7: L271E

   Promoter

   hSyn1

   Available since

   June 9, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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5. pAAV hSyn1 CaRhGC wt T2A tDimer

   Plasmid

   #101720

   Purpose

   humanized, Neuron-specific promoter driven expression of the rhodopsin guanylyl cyclase from Catenaria anguillulae with a neuron-specific promoter. Useful for raising intracellular cAMP close to the m

   Depositor

   Thomas Oertner

   Article

   Scheib et al Nat Commun. 2018 May 24;9(1):2046. doi:

   Inserts

   CatRhGC
   red fluorescent protein
   

   Use

   AAV

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   hSyn1 and ribosomal skip sequence T2A

   Available since

   Jan. 2, 2018

   Availability

   Academic Institutions and Nonprofits only

   

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6. pOTTC533 - pAAV SYN1 eGFP-2A-mKv1.2

   Plasmid

   #75295

   Purpose

   An AAV packaging vector that expresses eGFP and Kv1.2 under the control of a neuronal promoter.

   Depositor

   Brandon Harvey

   Insert

   eGFP-2A-mKv1.2 (Kcna2 Synthetic, Mouse)
   

   Use

   AAV

   Tags

   Expression

   Mutation

   Promoter

   human SYN1

   Available since

   Jan. 22, 2019

   Availability

   Academic Institutions and Nonprofits only

   

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7. pAAV hSyn1 CaRhAC T2A tDimer

   Plasmid

   #101722

   Purpose

   - humanized - variant of pAAV hSyn YFP-CaRhAC Addgene # 101721– less reliable in hippocampal neurons

   Depositor

   Thomas Oertner

   Article

   Scheib et al Nat Commun. 2018 May 24;9(1):2046. doi:

   Inserts

   CatRhAC
   red fluorescent protein
   

   Use

   AAV

   Tags

   Expression

   Mutation

   E497K,C569D

   Promoter

   human Synapsin1 promotor and ribosomal skip seque…

   Available since

   Jan. 2, 2018

   Availability

   Academic Institutions and Nonprofits only

   

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8. pOTTC1617 pAAV SYN1 Nuc-EYFP

   Plasmid

   #135567

   Purpose

   An AAV vector expressing a neuronally expressed nuclear EYFP reporter

   Depositor

   Christopher Richie

   Article

   Venniro et al Proc Natl Acad Sci U S A. 2020 Apr 7;117

   Inserts

   empty
   Nuc-EYFP
   

   Use

   AAV

   Tags

   3xNLS

   Expression

   Mammalian

   Mutation

   Promoter

   hSYN1

   Available since

   Sept. 1, 2021

   Availability

   Academic Institutions and Nonprofits only

   

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9. AAV-U6-sgLacZ-U6-sgGFP-hSyn1-mCherry

   Plasmid

   #208834

   Purpose

   Control plasmid expresses mCherry under the hSyn1 promoter with sgRNAs against LacZ and GFP

   Depositor

   Ben Emery

   Article

   Duncan et al Nat Commun. 2024 Oct 23;15(1):9148. doi:

   Insert

   mCherry
   

   Use

   AAV and CRISPR

   Tags

   Expression

   Bacterial and Mammalian

   Mutation

   Promoter

   hSyn1

   Available since

   Oct. 23, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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10. AAV-U6-sgMap3K12(1)-U6-sgMap3K12(2)-hSyn1-mCherry

    Plasmid

    #208835

    Purpose

    Knockout of Map3K12 (DLK) using tandem sgRNAs, expresses mCherry under the hSyn1 promoter

    Depositor

    Ben Emery

    Article

    Duncan et al Nat Commun. 2024 Oct 23;15(1):9148. doi:

    Insert

    mCherry
    

    Use

    AAV and CRISPR

    Tags

    Expression

    Bacterial and Mammalian

    Mutation

    Promoter

    hSyn1

    Available since

    Oct. 23, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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