We narrowed to 3,089 results for: sam

1. lentiSAMv2 rs11257655-guide2

   Plasmid

   #118205

   Purpose

   CRISPR-mediated activation of human islet enhancer containing T2D-associated variant rs11257655 (CDC123/CAMK1D GWAS locus)

   Depositor

   Jorge Ferrer

   Article

   Miguel-Escalada et al Nat Genet. 2019 Jun 28. pii: 10.1038/s41

   Insert

   dCas9-VP64-2A-BlastR
   

   Use

   CRISPR and Lentiviral

   Expression

   Mammalian

   Promoter

   EF1a core and U6

   Available Since

   April 3, 2019

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

2. lentiSAMv2 BFP-guide1

   Plasmid

   #118165

   Purpose

   CRISPRa negative control. Catalytically inactive Cas9 from S. pyogenes and VP64 with 2A-BlastR, and sgRNA1 against the BFP CDS

   Depositor

   Jorge Ferrer

   Article

   Miguel-Escalada et al Nat Genet. 2019 Jun 28. pii: 10.1038/s41

   Insert

   dCas9-VP64-2A-BlastR
   

   Use

   CRISPR and Lentiviral

   Expression

   Mammalian

   Promoter

   EF1a core and U6

   Available Since

   April 3, 2019

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

3. lentiSAMv2 rs11257655-guide4

   Plasmid

   #118207

   Purpose

   CRISPR-mediated activation of human islet enhancer containing T2D-associated variant rs11257655 (CDC123/CAMK1D GWAS locus)

   Depositor

   Jorge Ferrer

   Article

   Miguel-Escalada et al Nat Genet. 2019 Jun 28. pii: 10.1038/s41

   Insert

   dCas9-VP64-2A-BlastR
   

   Use

   CRISPR and Lentiviral

   Expression

   Mammalian

   Promoter

   EF1a core and U6

   Available Since

   April 2, 2019

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

4. lentiSAMv2 rs11257655-guide3

   Plasmid

   #118206

   Purpose

   CRISPR-mediated activation of human islet enhancer containing T2D-associated variant rs11257655 (CDC123/CAMK1D GWAS locus)

   Depositor

   Jorge Ferrer

   Article

   Miguel-Escalada et al Nat Genet. 2019 Jun 28. pii: 10.1038/s41

   Insert

   dCas9-VP64-2A-BlastR
   

   Use

   CRISPR and Lentiviral

   Expression

   Mammalian

   Promoter

   EF1a core and U6

   Available Since

   April 2, 2019

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

5. lentiSAMv2 rs7903146-guide3

   Plasmid

   #118204

   Purpose

   CRISPR-mediated activation of human islet enhancer containing T2D-associated variant rs7903146 (TCF7L2 GWAS locus)

   Depositor

   Jorge Ferrer

   Article

   Miguel-Escalada et al Nat Genet. 2019 Jun 28. pii: 10.1038/s41

   Insert

   dCas9-VP64-2A-BlastR
   

   Use

   CRISPR and Lentiviral

   Expression

   Mammalian

   Promoter

   EF1a core and U6

   Available Since

   April 2, 2019

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

6. lentiSAMv2 EGFP-guide3

   Plasmid

   #118168

   Purpose

   CRISPRa negative control. Catalytically inactive Cas9 from S. pyogenes and VP64 with 2A-BlastR, and sgRNA3 against the EGFP CDS

   Depositor

   Jorge Ferrer

   Article

   Miguel-Escalada et al Nat Genet. 2019 Jun 28. pii: 10.1038/s41

   Insert

   dCas9-VP64-2A-BlastR
   

   Use

   CRISPR and Lentiviral

   Expression

   Mammalian

   Promoter

   EF1a core and U6

   Available Since

   March 29, 2019

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

7. sgRNA(MS2)_Prnp_SAM2

   Plasmid

   #78625

   Purpose

   Encodes sgRNA2.0 targeting 138nt upstream of TSS

   Depositor

   Walker Jackson

   Article

   Kaczmarczyk et al PLoS One. 2016 Apr 29;11(4):e0154604. do

   Insert

   sgRNA(MS2)_Prnp_SAM2 (Prnp Mouse)
   

   Use

   CRISPR

   Expression

   Mammalian

   Promoter

   U6

   Available Since

   July 19, 2016

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

8. sgRNA(MS2)_Prnp_SAM1

   Plasmid

   #78624

   Purpose

   Encodes sgRNA2.0 targeting 158nt upstream of TSS

   Depositor

   Walker Jackson

   Article

   Kaczmarczyk et al PLoS One. 2016 Apr 29;11(4):e0154604. do

   Insert

   sgRNA(MS2)_Prnp_SAM2 (Prnp Mouse)
   

   Use

   CRISPR

   Expression

   Mammalian

   Promoter

   U6

   Available Since

   July 19, 2016

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

9. pGCDNsam-Hnf4a-IRES-GFP

   Plasmid

   #33006

   Depositor

   Atsushi Suzuki

   Article

   Sekiya et al Nature. 2011 Jun 29;475(7356):390-3. doi

   Insert

   hepatic nuclear factor 4 alpha (Hnf4a Mouse)
   

   Use

   Retroviral

   Available Since

   March 6, 2012

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

10. pGCDNsam-Foxa1-IRES-GFP

    Plasmid

    #33007

    Depositor

    Atsushi Suzuki

    Article

    Sekiya et al Nature. 2011 Jun 29;475(7356):390-3. doi

    Insert

    forkhead box A1 (Foxa1 Mouse)
    

    Use

    Retroviral

    Available Since

    March 6, 2012

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

11. pKVL2-U6gRNA_SAM(BbsI)-PGKpuroBFP-W

    Plasmid

    #112925

    Purpose

    Lentiviral vector for SAM-CRISPRa gRNA expression with puroBFP

    Depositor

    Kosuke Yusa

    Article

    Chong et al Genome Biol. 2018 Nov 26;19(1):205. doi:

    Insert

    hU6 promoter, gRNA-SAM expression cassette
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Available Since

    Sept. 4, 2019

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

12. pGCDNsam-Foxa2-IRES-GFP

    Plasmid

    #33008

    Depositor

    Atsushi Suzuki

    Article

    Sekiya et al Nature. 2011 Jun 29;475(7356):390-3. doi

    Insert

    forkhead box A2 (Foxa2 Mouse)
    

    Use

    Retroviral

    Available Since

    March 6, 2012

    Availability

    Academic Institutions and Nonprofits only

13. pGCDNsam-Foxa3-IRES-GFP

    Plasmid

    #33009

    Depositor

    Atsushi Suzuki

    Article

    Sekiya et al Nature. 2011 Jun 29;475(7356):390-3. doi

    Insert

    forkhead box A3 (Foxa3 Mouse)
    

    Use

    Retroviral

    Available Since

    March 6, 2012

    Availability

    Academic Institutions and Nonprofits only

14. CAG::PSAML141F:GlyR-IRES-GFP

    Plasmid

    #32478

    Purpose

    Expresses PSAM-GlyR (L141F) neuronal inhibitor, with IRES-EGFP marker

    Depositor

    Scott Sternson

    Article

    Magnus et al Science. 2011 Sep 2;333(6047):1292-6.

    Insert

    PSAML141F-GlyR
    

    Tags

    IRES-GFP

    Expression

    Mammalian

    Promoter

    CAG

    Available Since

    April 10, 2012

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

15. lentiSAMv2 OPTN TSS-guide4

    Plasmid

    #118199

    Purpose

    CRISPR-mediated activation of OPTN. Catalytically inactive Cas9 from S. pyogenes and VP64 with 2A-BlastR.

    Depositor

    Jorge Ferrer

    Article

    Miguel-Escalada et al Nat Genet. 2019 Jun 28. pii: 10.1038/s41

    Insert

    dCas9-VP64-2A-BlastR
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Promoter

    EF1a core and U6

    Available Since

    April 3, 2019

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

16. CAG::PSAMQ79G:GlyR-IRES-GFP

    Plasmid

    #32482

    Purpose

    Expresses PSAM-GlyR (Q79G) neuronal inhibitor, with IRES-EGFP marker

    Depositor

    Scott Sternson

    Article

    Magnus et al Science. 2011 Sep 2;333(6047):1292-6.

    Insert

    PSAMQ79G-GlyR
    

    Tags

    IRES-EGFP

    Expression

    Mammalian

    Promoter

    CAG

    Available Since

    April 11, 2012

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

17. lentiSAMv2 ZBED3-TSS-guide1

    Plasmid

    #125506

    Purpose

    CRISPR-mediated activation of ZBED3. Catalytically inactive Cas9 from S. pyogenes and VP64 with 2A-BlastR.

    Depositor

    Jorge Ferrer

    Article

    Miguel-Escalada et al Nat Genet. 2019 Jun 28. pii: 10.1038/s41

    Insert

    dCas9-VP64-2A-BlastR
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Promoter

    EF1a core and U6

    Available Since

    July 25, 2019

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

18. lentiSAMv2 CRY2-TSS-guide3

    Plasmid

    #125491

    Purpose

    CRISPR-mediated activation of CRY2. Catalytically inactive Cas9 from S. pyogenes and VP64 with 2A-BlastR.

    Depositor

    Jorge Ferrer

    Article

    Miguel-Escalada et al Nat Genet. 2019 Jun 28. pii: 10.1038/s41

    Insert

    dCas9-VP64-2A-BlastR
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Promoter

    EF1a core and U6

    Available Since

    July 25, 2019

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

19. lentiSAMv2 CRY2-TSS-guide2

    Plasmid

    #125490

    Purpose

    CRISPR-mediated activation of CRY2. Catalytically inactive Cas9 from S. pyogenes and VP64 with 2A-BlastR.

    Depositor

    Jorge Ferrer

    Article

    Miguel-Escalada et al Nat Genet. 2019 Jun 28. pii: 10.1038/s41

    Insert

    dCas9-VP64-2A-BlastR
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Promoter

    EF1a core and U6

    Available Since

    July 25, 2019

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

20. lentiSAMv2 TCF7L2 TSS-guide1

    Plasmid

    #118184

    Purpose

    CRISPR-mediated activation of TCF7L2. Catalytically inactive Cas9 from S. pyogenes and VP64 with 2A-BlastR.

    Depositor

    Jorge Ferrer

    Article

    Miguel-Escalada et al Nat Genet. 2019 Jun 28. pii: 10.1038/s41

    Insert

    dCas9-VP64-2A-BlastR
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Promoter

    EF1a core and U6

    Available Since

    April 5, 2019

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge