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pUC_cohNaV1.1_2009aa_IRES2_GFP

Plasmid

#227642

Purpose

Expresses Nav 1.1 and IRES-GFP

Depositor

Dravet Syndrome Foundation Spain

Insert

NaV1.1 (SCN1A Human)

Use

Tags

IRES-GFP

Expression

Mammalian

Mutation

Promoter

Available since

Jan. 16, 2025

Availability

Academic Institutions and Nonprofits only

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hNav1.8_pcDNA3.1

Plasmid

#182847

Purpose

Expresses hNav1.8 in mammalian cells

Depositor

Paul DeCaen

Article

McCollum et al Cell Rep. 2022 Aug 23;40(8):111248. doi:

Insert

SCN10A (SCN10A Human)

Use

Tags

Expression

Mammalian

Mutation

Promoter

Available since

April 1, 2025

Availability

Academic Institutions and Nonprofits only

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Pt NaV1.4

Plasmid

#200233

Purpose

Expression in mammalian cells or oocytes

Depositor

Dan Minor

Article

Abderemane-Ali et al J Gen Physiol. 2021 Sep 6;153(9):e202112

Insert

Phyllobates terriblis NaV1.4 – muscle channel

Use

Tags

Expression

Mammalian

Mutation

Promoter

CMV and T7

Available since

Sept. 10, 2024

Availability

Academic Institutions and Nonprofits only

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Dt NaV1.4

Plasmid

#200250

Purpose

Expression in mammalian cells or oocytes

Depositor

Dan Minor

Article

Abderemane-Ali et al J Gen Physiol. 2021 Sep 6;153(9):e202112

Insert

Dendrobates tinctorius NaV1.4 – muscle channel

Use

Tags

Expression

Mammalian

Mutation

Promoter

CMV and T7

Available since

Sept. 10, 2024

Availability

Academic Institutions and Nonprofits only

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psgRNAv1-empty

Plasmid

#171611

Purpose

sgRNA_v1 plasmid for AsCas12f1 in bacteria

Depositor

Quanjiang Ji

Article

Wu et al Nat Chem Biol. 2021 Sep 2. pii: 10.1038/

Insert

AsCas12f1_sgRNA_1

Use

Tags

Expression

Bacterial

Mutation

Promoter

Available since

Sept. 10, 2021

Availability

Academic Institutions and Nonprofits only

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Pum NaV1.4

Plasmid

#200230

Purpose

Expression in mammalian cells or oocytes

Depositor

Dan Minor

Article

Abderemane-Ali et al J Gen Physiol. 2021 Sep 6;153(9):e202112

Insert

Pitohui uropygialis meridionalis NaV1.4

Use

Tags

Expression

Mammalian

Mutation

Promoter

CMV and T7

Available since

Sept. 10, 2024

Availability

Academic Institutions and Nonprofits only

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Pum NaV1.5

Plasmid

#200232

Purpose

Expression in mammalian cells or oocytes

Depositor

Dan Minor

Article

Abderemane-Ali et al J Gen Physiol. 2021 Sep 6;153(9):e202112

Insert

Pitohui uropygialis meridionalis Nav1.5

Use

Tags

Expression

Mammalian

Mutation

Promoter

CMV and T7

Available since

Sept. 10, 2024

Availability

Academic Institutions and Nonprofits only

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Pt NaV1.4-N1600T

Plasmid

#200289

Purpose

Expression in mammalian cells or oocytes

Depositor

Dan Minor

Article

Abderemane-Ali et al J Gen Physiol. 2021 Sep 6;153(9):e202112

Insert

Phyllobates terriblis NaV1.4 – muscle channel

Use

Tags

Expression

Mammalian

Mutation

N1600T

Promoter

CMV and T7

Available since

Sept. 10, 2024

Availability

Academic Institutions and Nonprofits only

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Dt NaV1.4-N1600T

Plasmid

#200308

Purpose

Expression in mammalian cells or oocytes

Depositor

Dan Minor

Article

Abderemane-Ali et al J Gen Physiol. 2021 Sep 6;153(9):e202112

Insert

Dendrobates tinctorius NaV1.4 – muscle channel

Use

Tags

Expression

Mammalian

Mutation

N1600T

Promoter

CMV and T7

Available since

Sept. 10, 2024

Availability

Academic Institutions and Nonprofits only

Enlarge
Pum NaV1.4-N432T

Plasmid

#200284

Purpose

Expression in mammalian cells or oocytes

Depositor

Dan Minor

Article

Abderemane-Ali et al J Gen Physiol. 2021 Sep 6;153(9):e202112

Insert

Pitohui uropygialis meridionalis NaV1.4

Use

Tags

Expression

Mammalian

Mutation

N432T

Promoter

CMV and T7

Available since

Sept. 10, 2024

Availability

Academic Institutions and Nonprofits only

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Pum NaV1.4-N830T

Plasmid

#200285

Purpose

Expression in mammalian cells or oocytes

Depositor

Dan Minor

Article

Abderemane-Ali et al J Gen Physiol. 2021 Sep 6;153(9):e202112

Insert

Pitohui uropygialis meridionalis NaV1.4

Use

Tags

Expression

Mammalian

Mutation

N830T

Promoter

CMV and T7

Available since

Sept. 10, 2024

Availability

Academic Institutions and Nonprofits only

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Pum NaV1.4-N11306T

Plasmid

#200286

Purpose

Expression in mammalian cells or oocytes

Depositor

Dan Minor

Article

Abderemane-Ali et al J Gen Physiol. 2021 Sep 6;153(9):e202112

Insert

Pitohui uropygialis meridionalis NaV1.4

Use

Tags

Expression

Mammalian

Mutation

N11306T

Promoter

CMV and T7

Available since

Sept. 10, 2024

Availability

Academic Institutions and Nonprofits only

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Pum NaV1.4-N1609T

Plasmid

#200287

Purpose

Expression in mammalian cells or oocytes

Depositor

Dan Minor

Article

Abderemane-Ali et al J Gen Physiol. 2021 Sep 6;153(9):e202112

Insert

Pitohui uropygialis meridionalis NaV1.4

Use

Tags

Expression

Mammalian

Mutation

N1609T

Promoter

CMV and T7

Available since

Sept. 10, 2024

Availability

Academic Institutions and Nonprofits only

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Pum NaV1.4-N1609A

Plasmid

#200288

Purpose

Expression in mammalian cells or oocytes

Depositor

Dan Minor

Article

Abderemane-Ali et al J Gen Physiol. 2021 Sep 6;153(9):e202112

Insert

Pitohui uropygialis meridionalis NaV1.4

Use

Tags

Expression

Mammalian

Mutation

N1609A

Promoter

CMV and T7

Available since

Sept. 10, 2024

Availability

Academic Institutions and Nonprofits only

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Anti-Nav1.4 Na+ channel [N255/38]

Plasmid

#190306

Purpose

Mammalian Expression Plasmid of anti-Nav1.4 Na+ channel (Rat). Derived from hybridoma N255/38.

Depositor

James Trimmer

Article

Mitchell et al Sci Rep. 2023 Sep 27;13(1):16200. doi: 1

Insert

anti-Nav1.4 Na+ channel (Rattus norvegicus) recombinant Mouse monoclonal antibody (Scn4a Mouse)

Use

Tags

Expression

Mammalian

Mutation

Promoter

Dual CMV

Available since

Nov. 1, 2022

Availability

Academic Institutions and Nonprofits only

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Nav1.7 Na+ channel scFv [N68/6]

Plasmid

#182094

Purpose

Mammalian Expression of Nav1.7 Na+ channel scFv. Derived from hybridoma N68/6.

Depositor

James Trimmer

Article

Mitchell et al Sci Rep. 2023 Sep 27;13(1):16200. doi: 1

Insert

recombinant mouse scFv targeting Nav1.7 Na+ channel (Homo sapiens) (SCN9A Mouse)

Use

Tags

6xHis

Expression

Mammalian

Mutation

Promoter

CMV

Available since

March 25, 2022

Availability

Academic Institutions and Nonprofits only

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Nav1.8 Na+ channel scFv [N134/12]

Plasmid

#190530

Purpose

Mammalian Expression of Nav1.8 Na+ channel scFV. Derived from hybridoma N134/12.

Depositor

James Trimmer

Article

Mitchell et al Sci Rep. 2023 Sep 27;13(1):16200. doi: 1

Insert

Nav1.8 Na+ channel (Rattus norvegicus) recombinant scFV (Scn10a Mouse)

Use

Tags

Sortase, 6xHis

Expression

Mammalian

Mutation

Promoter

CMV

Available since

Nov. 1, 2022

Availability

Academic Institutions and Nonprofits only

Enlarge
Anti-Nav1.7 Na+ channel [N68/6R]

Plasmid

#177566

Purpose

Mammalian Expression Plasmid of anti-Nav1.7 Na+ channel (Human). Derived from hybridoma N68/6.

Depositor

James Trimmer

Article

Mitchell et al Sci Rep. 2023 Sep 27;13(1):16200. doi: 1

Insert

anti-Nav1.7 Na+ channel (Homo sapiens) recombinant mouse monoclonal antibody (SCN9A Mouse)

Use

Tags

Expression

Mammalian

Mutation

Promoter

Dual CMV

Available since

Nov. 24, 2021

Availability

Academic Institutions and Nonprofits only

Enlarge
Nav1.8 Na+ channel scFv [N134/12]

Plasmid

#190531

Purpose

Mammalian Expression of Nav1.8 Na+ channel scFV. Derived from hybridoma N134/12.

Depositor

James Trimmer

Article

Mitchell et al Sci Rep. 2023 Sep 27;13(1):16200. doi: 1

Insert

Nav1.8 Na+ channel (Rattus norvegicus) recombinant scFV (Scn10a Mouse)

Use

Tags

HA, Sortase, 6xHis

Expression

Mammalian

Mutation

Promoter

CMV

Available since

Nov. 1, 2022

Availability

Academic Institutions and Nonprofits only

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Nav1.5_1-2linker411-717_PPSYtoAASA1960-1996

Plasmid

#187732

Purpose

Express a chimera of the Nav1.5 linker between the first and second transmembrane domain with the motif surrounding PPSY; residues 1974-1977 PPSY mutated to AASA

Depositor

Sandra Gabelli

Article

Wright et al J Biol Chem. 2024 Mar;300(3):105715. doi

Insert

Nav1.5 1,2linker residues 411-717 and Nav1.5 residues 1960-1996 PPSY mutated to AASA (SCN5A Human)

Use

Tags

His-TEV

Expression

Bacterial

Mutation

deletion of residues 1-410 and 718-1959 and 1997-…

Promoter

Available since

Oct. 24, 2024

Availability

Academic Institutions and Nonprofits only

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