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DNA repair library with 336 sgRNAs

Pooled Library

#177664

Purpose

CRISPR-interference (CRISPRi) library of 366 sgRNAs targeting 118 genes encoding factors involved in DNA repair and associated processes

Depositor

Brittany Adamson

Article

Hussmann et al Cell. 2021 Oct 28;184(22):5653-5669.e25.

Species

Homo sapiens

Use

CRISPR

Available since

Nov. 29, 2023

Availability

Academic Institutions and Nonprofits only
Human sgRNA library Brunello in lentiGuide-Puro

Pooled Library

#73178

Purpose

Human sgRNA library in backbone lentiGuide-Puro targeting 19,114 genes and containing 76,441 unique sgRNAs along with 1000 non-targeting controls

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Has Service

Lentiviral Prep

Expression

Mammalian

Use

CRISPR and Lentiviral

Available since

Feb. 9, 2016

Availability

Academic Institutions and Nonprofits only
Mouse sgRNA library Brie in lentiGuide-Puro

Pooled Library

#73633

Purpose

Mouse sgRNA library in backbone lentiGuide-Puro containing 78,637 unique sgRNAs targeting 19,674 genes along with 1000 non-targeting controls

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Has Service

Lentiviral Prep

Expression

Mammalian

Use

CRISPR and Lentiviral

Available since

Feb. 25, 2016

Availability

Academic Institutions and Nonprofits only
Human Epigenetic Knockout Library

Pooled Library

#162256

Purpose

Lentiviral CRISPR library targets human epigenetic genes

Depositor

Kivanc Birsoy

Article

Williams et al Cell Metab. 2020 Apr 7;31(4):852-861.e6.

Expression

Mammalian

Species

Homo sapiens

Use

CRISPR and Lentiviral

Available since

Nov. 17, 2020

Availability

Academic Institutions and Nonprofits only
Human Brunello kinome pooled library, guides 1-4 in lentiGuide-Puro backbone

Pooled Library

#75312

Purpose

Human sgRNA library in backbone lentiGuide-Puro targeting 763 kinase genes and containing 3,052 unique sgRNAs along with 100 non-targeting controls

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Expression

Mammalian

Use

CRISPR and Lentiviral

Available since

June 27, 2016

Availability

Academic Institutions and Nonprofits only
DNA repair library with 1,513 sgRNAs

Pooled Library

#177670

Purpose

CRISPR-interference (CRISPRi) library designed to target 476 genes involved in DNA repair and associated processes. It contains 1,513 sgRNAs and 60 non-targeting control sgRNAs.

Depositor

Brittany Adamson

Article

Chen et al Cell. 2021 Oct 28;184(22):5635-5652.e29.

Expression

Mammalian

Species

Homo sapiens

Use

CRISPR and Lentiviral

Available since

July 11, 2023

Availability

Academic Institutions and Nonprofits only
Human Brunello kinome pooled library, guides 5-8 in lentiGuide-Puro backbone

Pooled Library

#75313

Purpose

Human sgRNA library in backbone lentiGuide-Puro targeting 763 kinase genes and containing 3,052 unique sgRNAs along with 100 non-targeting controls

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Expression

Mammalian

Use

CRISPR and Lentiviral

Available since

June 27, 2016

Availability

Academic Institutions and Nonprofits only
Murine cell surface protein knockout (McspKO) library

Pooled Library

#200445

Purpose

A CRISPR library targeting 1,157 cell surface genes and 98 control genes with four sgRNAs per gene

Depositor

Junjie Chen

Article

Wang et al Proc Natl Acad Sci U S A. 2022 Jun 21;11

Expression

Mammalian

Species

Mus musculus

Use

CRISPR, Lentiviral, and Mouse Targeting

Available since

Oct. 26, 2023

Availability

Academic Institutions and Nonprofits only
Mouse SLC KO Library

Pooled Library

#141436

Purpose

Expresses gRNAs for knockout of the mouse Solute Carrier family

Depositor

Giulio Superti-Furga

Expression

Mammalian

Species

Mus musculus

Use

CRISPR and Lentiviral

Available since

May 18, 2020

Availability

Academic Institutions and Nonprofits only
LX-miR

Pooled Library

#112200

Purpose

gRNA library targets human primary miRNAs

Depositor

Ren-Jang Lin

Article

Kurata et al RNA. 2018 May 2. pii: rna.066282.118. do

Expression

Mammalian

Species

Homo sapiens

Use

Lentiviral

Available since

Sept. 20, 2018

Availability

Academic Institutions and Nonprofits only
Mouse Cherry Brie Pooled Library

Pooled Library

#170511

Purpose

CRISPR library targeting mouse genes

Depositor

Pavel Tolar

Article

Newman et al biorXiv 2021.03.02.433398

Expression

Mammalian

Species

Synthetic

Use

CRISPR and Lentiviral

Available since

Sept. 9, 2021

Availability

Academic Institutions and Nonprofits only
E.coli_GW-sgRNA_Lib3

Pooled Library

#113136

Purpose

Genome-wide gRNA library for E. coli, sub3

Depositor

Chong Zhang

Article

Wang et al Nat Commun. 2018 Jun 26;9(1):2475. doi:

Expression

Bacterial

Available since

May 14, 2019

Availability

Academic Institutions and Nonprofits only
E.coli_GW-sgRNA_Lib1

Pooled Library

#113134

Purpose

Genome-wide gRNA library for E. coli, sub1

Depositor

Chong Zhang

Article

Wang et al Nat Commun. 2018 Jun 26;9(1):2475. doi:

Expression

Bacterial

Available since

May 14, 2019

Availability

Academic Institutions and Nonprofits only
E.coli_GW-sgRNA_Lib4

Pooled Library

#113137

Purpose

Genome-wide gRNA library for E. coli, sub4

Depositor

Chong Zhang

Article

Wang et al Nat Commun. 2018 Jun 26;9(1):2475. doi:

Expression

Bacterial

Available since

May 14, 2019

Availability

Academic Institutions and Nonprofits only
E.coli_GW-sgRNA_Lib2

Pooled Library

#113135

Purpose

Genome-wide gRNA library for E. coli, sub2

Depositor

Chong Zhang

Article

Wang et al Nat Commun. 2018 Jun 26;9(1):2475. doi:

Expression

Bacterial

Available since

May 14, 2019

Availability

Academic Institutions and Nonprofits only
E.coli_NC_sgRNA_lib

Pooled Library

#113146

Purpose

Genome-wide gRNA library for E. coli, non-targeting control

Depositor

Chong Zhang

Article

Wang et al Nat Commun. 2018 Jun 26;9(1):2475. doi:

Expression

Bacterial

Available since

May 14, 2019

Availability

Academic Institutions and Nonprofits only
Membrane protein gRNA library

Pooled Library

#113345

Purpose

Contains 58,071 gRNAs targeting 6,213 membrane proteins and 500 non-targeting gRNAs

Depositor

Gavin Wright

Article

Chong et al Genome Biol. 2018 Nov 26;19(1):205. doi:

Species

Homo sapiens

Use

Lentiviral

Available since

Jan. 4, 2019

Availability

Academic Institutions and Nonprofits only
Sctrans-PP

Pooled Library

#153101

Purpose

CRISPR library targets all non-essential and conditionally essential transporter genes in S. cerevisiae

Depositor

Irina Borodina

Article

Wang et al Metab Eng. 2021 Jan 16. pii: S1096-7176(

Expression

Yeast

Species

Saccharomyces cerevisiae

Use

CRISPR

Available since

Jan. 20, 2021

Availability

Academic Institutions and Nonprofits only
Sctrans-PP-Grp1

Pooled Library

#153102

Purpose

CRISPR library targets a sub-pool of transporter genes in S. cerevisiae

Depositor

Irina Borodina

Article

Wang et al Metab Eng. 2021 Jan 16. pii: S1096-7176(

Expression

Yeast

Species

Saccharomyces cerevisiae

Use

CRISPR

Available since

Jan. 20, 2021

Availability

Academic Institutions and Nonprofits only
Sctrans-PP-Grp2

Pooled Library

#153103

Purpose

CRISPR library targets a sub-pool of transporter genes in S. cerevisiae

Depositor

Irina Borodina

Article

Wang et al Metab Eng. 2021 Jan 16. pii: S1096-7176(

Expression

Yeast

Species

Saccharomyces cerevisiae

Use

CRISPR

Available since

Jan. 20, 2021

Availability

Academic Institutions and Nonprofits only

Showing: 181 - 200 of 276 results

Results per page:

Sort results by:

DNA repair library with 336 sgRNAs

Human sgRNA library Brunello in lentiGuide-Puro

Mouse sgRNA library Brie in lentiGuide-Puro

Human Epigenetic Knockout Library

Human Brunello kinome pooled library, guides 1-4 in lentiGuide-Puro backbone

DNA repair library with 1,513 sgRNAs

Human Brunello kinome pooled library, guides 5-8 in lentiGuide-Puro backbone

Murine cell surface protein knockout (McspKO) library

Mouse SLC KO Library

LX-miR

Mouse Cherry Brie Pooled Library

E.coli_GW-sgRNA_Lib3

E.coli_GW-sgRNA_Lib1

E.coli_GW-sgRNA_Lib4

E.coli_GW-sgRNA_Lib2

E.coli_NC_sgRNA_lib

Membrane protein gRNA library

Sctrans-PP

Sctrans-PP-Grp1

Sctrans-PP-Grp2

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