We narrowed to 279 results for: Spr

1. Pan-Druggable Cancer Library

   Pooled Library

   #182133

   Purpose

   All-in-one CRISPR/Cas system with 74 individual elements. 63 elements target cancer-related genes with FDA-approved drug treatments, and 3 elements target key medulloblastoma driver genes.

   Depositor

   Prashant Mali

   Article

   Hu et al Biomaterials. 2022 Jan;280:121276. doi:

   Species

   Homo sapiens

   Use

   CRISPR and Lentiviral

   Available since

   Aug. 26, 2022

   Availability

   Academic Institutions and Nonprofits only

2. DNA repair library with 336 sgRNAs

   Pooled Library

   #177664

   Purpose

   CRISPR-interference (CRISPRi) library of 366 sgRNAs targeting 118 genes encoding factors involved in DNA repair and associated processes

   Depositor

   Brittany Adamson

   Article

   Hussmann et al Cell. 2021 Oct 28;184(22):5653-5669.e25.

   Species

   Homo sapiens

   Use

   CRISPR

   Available since

   Nov. 29, 2023

   Availability

   Academic Institutions and Nonprofits only

3. Human sgRNA library Brunello in lentiGuide-Puro

   Pooled Library

   #73178

   Purpose

   Human sgRNA library in backbone lentiGuide-Puro targeting 19,114 genes and containing 76,441 unique sgRNAs along with 1000 non-targeting controls

   Depositor

   David Root, John Doench

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Has Service

   Lentiviral Prep

   Expression

   Mammalian

   Use

   CRISPR and Lentiviral

   Available since

   Feb. 9, 2016

   Availability

   Academic Institutions and Nonprofits only

4. Human Epigenetic Knockout Library

   Pooled Library

   #162256

   Purpose

   Lentiviral CRISPR library targets human epigenetic genes

   Depositor

   Kivanc Birsoy

   Article

   Williams et al Cell Metab. 2020 Apr 7;31(4):852-861.e6.

   Expression

   Mammalian

   Species

   Homo sapiens

   Use

   CRISPR and Lentiviral

   Available since

   Nov. 17, 2020

   Availability

   Academic Institutions and Nonprofits only

5. Mouse sgRNA library Brie in lentiGuide-Puro

   Pooled Library

   #73633

   Purpose

   Mouse sgRNA library in backbone lentiGuide-Puro containing 78,637 unique sgRNAs targeting 19,674 genes along with 1000 non-targeting controls

   Depositor

   David Root, John Doench

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Has Service

   Lentiviral Prep

   Expression

   Mammalian

   Use

   CRISPR and Lentiviral

   Available since

   Feb. 25, 2016

   Availability

   Academic Institutions and Nonprofits only

6. Human Brunello kinome pooled library, guides 1-4 in lentiGuide-Puro backbone

   Pooled Library

   #75312

   Purpose

   Human sgRNA library in backbone lentiGuide-Puro targeting 763 kinase genes and containing 3,052 unique sgRNAs along with 100 non-targeting controls

   Depositor

   David Root, John Doench

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Expression

   Mammalian

   Use

   CRISPR and Lentiviral

   Available since

   June 27, 2016

   Availability

   Academic Institutions and Nonprofits only

7. DNA repair library with 1,513 sgRNAs

   Pooled Library

   #177670

   Purpose

   CRISPR-interference (CRISPRi) library designed to target 476 genes involved in DNA repair and associated processes. It contains 1,513 sgRNAs and 60 non-targeting control sgRNAs.

   Depositor

   Brittany Adamson

   Article

   Chen et al Cell. 2021 Oct 28;184(22):5635-5652.e29.

   Expression

   Mammalian

   Species

   Homo sapiens

   Use

   CRISPR and Lentiviral

   Available since

   July 11, 2023

   Availability

   Academic Institutions and Nonprofits only

8. Human Brunello kinome pooled library, guides 5-8 in lentiGuide-Puro backbone

   Pooled Library

   #75313

   Purpose

   Human sgRNA library in backbone lentiGuide-Puro targeting 763 kinase genes and containing 3,052 unique sgRNAs along with 100 non-targeting controls

   Depositor

   David Root, John Doench

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Expression

   Mammalian

   Use

   CRISPR and Lentiviral

   Available since

   June 27, 2016

   Availability

   Academic Institutions and Nonprofits only

9. UMI-sgRNA-TF

   Pooled Library

   #234819

   Purpose

   Unique molecular identifiers-linked sgRNA library targeting transcription factors (TFs) in mice.

   Depositor

   Benjamin Ebert

   Article

   Loke et al Blood. 2025 Jun 10:blood.2024028033. doi

   Expression

   Mammalian

   Species

   Mus musculus

   Use

   CRISPR and Lentiviral

   Available since

   June 11, 2025

   Availability

   Academic Institutions and Nonprofits only

10. UMI-sgRNA-CH

    Pooled Library

    #234820

    Purpose

    Unique molecular identifiers-linked sgRNA library targeting chromatin factors (CH) in mice.

    Depositor

    Benjamin Ebert

    Article

    Loke et al Blood. 2025 Jun 10:blood.2024028033. doi

    Expression

    Mammalian

    Species

    Mus musculus

    Use

    CRISPR and Lentiviral

    Available since

    June 11, 2025

    Availability

    Academic Institutions and Nonprofits only

11. Murine cell surface protein knockout (McspKO) library

    Pooled Library

    #200445

    Purpose

    A CRISPR library targeting 1,157 cell surface genes and 98 control genes with four sgRNAs per gene

    Depositor

    Junjie Chen

    Article

    Wang et al Proc Natl Acad Sci U S A. 2022 Jun 21;11

    Expression

    Mammalian

    Species

    Mus musculus

    Use

    CRISPR, Lentiviral, and Mouse Targeting

    Available since

    Oct. 26, 2023

    Availability

    Academic Institutions and Nonprofits only

12. Mouse SLC KO Library

    Pooled Library

    #141436

    Purpose

    Expresses gRNAs for knockout of the mouse Solute Carrier family

    Depositor

    Giulio Superti-Furga

    Expression

    Mammalian

    Species

    Mus musculus

    Use

    CRISPR and Lentiviral

    Available since

    May 18, 2020

    Availability

    Academic Institutions and Nonprofits only

13. Mouse Cherry Brie Pooled Library

    Pooled Library

    #170511

    Purpose

    CRISPR library targeting mouse genes

    Depositor

    Pavel Tolar

    Article

    Newman et al biorXiv 2021.03.02.433398

    Expression

    Mammalian

    Species

    Synthetic

    Use

    CRISPR and Lentiviral

    Available since

    Sept. 9, 2021

    Availability

    Academic Institutions and Nonprofits only

14. LX-miR

    Pooled Library

    #112200

    Purpose

    gRNA library targets human primary miRNAs

    Depositor

    Ren-Jang Lin

    Article

    Kurata et al RNA. 2018 May 2. pii: rna.066282.118. do

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    Lentiviral

    Available since

    Sept. 20, 2018

    Availability

    Academic Institutions and Nonprofits only

15. E.coli_GW-sgRNA_Lib3

    Pooled Library

    #113136

    Purpose

    Genome-wide gRNA library for E. coli, sub3

    Depositor

    Chong Zhang

    Article

    Wang et al Nat Commun. 2018 Jun 26;9(1):2475. doi:

    Expression

    Bacterial

    Available since

    May 14, 2019

    Availability

    Academic Institutions and Nonprofits only

16. E.coli_GW-sgRNA_Lib1

    Pooled Library

    #113134

    Purpose

    Genome-wide gRNA library for E. coli, sub1

    Depositor

    Chong Zhang

    Article

    Wang et al Nat Commun. 2018 Jun 26;9(1):2475. doi:

    Expression

    Bacterial

    Available since

    May 14, 2019

    Availability

    Academic Institutions and Nonprofits only

17. E.coli_GW-sgRNA_Lib4

    Pooled Library

    #113137

    Purpose

    Genome-wide gRNA library for E. coli, sub4

    Depositor

    Chong Zhang

    Article

    Wang et al Nat Commun. 2018 Jun 26;9(1):2475. doi:

    Expression

    Bacterial

    Available since

    May 14, 2019

    Availability

    Academic Institutions and Nonprofits only

18. E.coli_GW-sgRNA_Lib2

    Pooled Library

    #113135

    Purpose

    Genome-wide gRNA library for E. coli, sub2

    Depositor

    Chong Zhang

    Article

    Wang et al Nat Commun. 2018 Jun 26;9(1):2475. doi:

    Expression

    Bacterial

    Available since

    May 14, 2019

    Availability

    Academic Institutions and Nonprofits only

19. E.coli_NC_sgRNA_lib

    Pooled Library

    #113146

    Purpose

    Genome-wide gRNA library for E. coli, non-targeting control

    Depositor

    Chong Zhang

    Article

    Wang et al Nat Commun. 2018 Jun 26;9(1):2475. doi:

    Expression

    Bacterial

    Available since

    May 14, 2019

    Availability

    Academic Institutions and Nonprofits only

20. Membrane protein gRNA library

    Pooled Library

    #113345

    Purpose

    Contains 58,071 gRNAs targeting 6,213 membrane proteins and 500 non-targeting gRNAs

    Depositor

    Gavin Wright

    Article

    Chong et al Genome Biol. 2018 Nov 26;19(1):205. doi:

    Species

    Homo sapiens

    Use

    Lentiviral

    Available since

    Jan. 4, 2019

    Availability

    Academic Institutions and Nonprofits only