We narrowed to 285 results for: Spr

1. CRASP-Seq Gene KO v1 empty

   Pooled Library

   #232069

   Purpose

   Flexible CRASP-Seq platform for studying splicing regulation. Used to study how protein coding genes impact splicing of minigene reporters.

   Depositor

   Thomas Gonatopoulos-Pournatzis

   Article

   Behera et al bioRxiv [Preprint]. 2025 Apr 26:2025.04.

   Expression

   Mammalian

   Species

   Homo sapiens

   Use

   CRISPR and Lentiviral

   Available Since

   Oct. 28, 2025

   Availability

   Academic Institutions and Nonprofits only

2. Mouse Brie kinome pooled library, guides 1-4 in lentiGuide-Puro backbone

   Pooled Library

   #75316

   Purpose

   Mouse sgRNA library in backbone lentiGuide-Puro targeting 713 kinase genes and containing 2,852 unique sgRNAs along with 100 non-targeting controls

   Depositor

   John Doench, David Root

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Available Since

   June 27, 2016

   Availability

   Academic Institutions and Nonprofits only

3. CRASP-Seq BE Tiling v1 empty

   Pooled Library

   #232070

   Purpose

   Tiling guides designed to target 39 splicing-related genes, along with several thousand control gRNAs. Optimized for CRASP-Seq experiments combined with high-throughput base editing mutagenesis.

   Depositor

   Thomas Gonatopoulos-Pournatzis

   Article

   Behera et al bioRxiv [Preprint]. 2025 Apr 26:2025.04.

   Expression

   Mammalian

   Species

   Homo sapiens

   Use

   CRISPR and Lentiviral

   Available Since

   Oct. 28, 2025

   Availability

   Academic Institutions and Nonprofits only

4. Bison sgRNA library

   Pooled Library

   #169942

   Purpose

   The BISON CRISPR library targets 713 E1, E2, and E3 ubiquitin ligases, deubiquitinases, and control genes and contains 2,852 guide RNAs. It was cloned into the pXPR003.

   Depositor

   Benjamin Ebert

   Article

   Slabicki et al Nature. 2020 Sep;585(7824):293-297. doi:

   Use

   Lentiviral

   Available Since

   Sept. 9, 2021

   Availability

   Academic Institutions and Nonprofits only

5. Mouse Chromatin Regulator Library

   Pooled Library

   #200011

   Purpose

   CRISPR KO library targeting a comprehensive set of genes with annotated function as chromatin regulators.

   Depositor

   Robert Manguso, Gabriel Griffin, Bradley Bernstein

   Article

   Griffin et al Nature. 2021 Jul;595(7866):309-314. doi:

   Expression

   Mammalian

   Use

   CRISPR and Lentiviral

   Available Since

   Dec. 15, 2023

   Availability

   Academic Institutions and Nonprofits only

6. pLCKO2::TKOv3

   Pooled Library

   #125517

   Purpose

   Human CRISPR lentiviral library containing 70,948 guides (4-5 guides/gene) targeting 18,053 human protein-coding genes, in a non-Cas9 containing backbone

   Depositor

   Jason Moffat

   Article

   Mair et al Cell Rep. 2019 Apr 9;27(2):599-615.e12.

   Expression

   Mammalian

   Species

   Homo sapiens

   Use

   CRISPR and Lentiviral

   Available Since

   Aug. 1, 2019

   Availability

   Academic Institutions and Nonprofits only

7. Toronto KnockOut Library (TKOv1)

   Pooled Library

   #1000000069

   Purpose

   CRISPR gRNA knockout pooled library for targeting the human genome

   Depositor

   Stephane Angers, Jason Moffat

   Available Since

   Jan. 28, 2016

   Availability

   Academic Institutions and Nonprofits only

8. Human SAM library in lentiSAMv2 backbone

   Pooled Library

   #1000000078

   Purpose

   Genome-wide CRISPR gRNA pooled library for activation of human genes

   Depositor

   Feng Zhang

   Available Since

   June 27, 2016

   Availability

   Academic Institutions and Nonprofits only

9. Human GeCKO Lentiviral sgRNA Library v2 (lentiGuide-Puro)

   Pooled Library

   #1000000049

   Purpose

   CRISPR gRNA knockout pooled library for targeting the human genome

   Depositor

   Feng Zhang

   Available Since

   May 8, 2014

   Availability

   Academic Institutions and Nonprofits only

10. Mouse GeCKO Lentiviral sgRNA Library (LentiGuide-Puro)

    Pooled Library

    #1000000053

    Purpose

    CRISPR gRNA knockout pooled library for targeting the mouse genome

    Depositor

    Feng Zhang

    Available Since

    July 23, 2014

    Availability

    Academic Institutions and Nonprofits only

11. Human SAM library in lenti sgRNA(MS2)_puro backbone

    Pooled Library

    #1000000074

    Purpose

    Genome-wide CRISPR gRNA pooled library for activation of mouse genes

    Depositor

    Feng Zhang

    Available Since

    March 17, 2016

    Availability

    Academic Institutions and Nonprofits only

12. Human SAM Library in lenti sgRNA(MS2)_zeo backbone

    Pooled Library

    #1000000057

    Purpose

    Genome-wide CRISPR gRNA pooled library for activation of human genes

    Depositor

    Feng Zhang

    Available Since

    Jan. 16, 2015

    Availability

    Academic Institutions and Nonprofits only

13. Mouse SAM Library in lenti sgRNA(MS2)_puro optimized backbone

    Pooled Library

    #1000000075

    Purpose

    Genome-wide CRISPR gRNA pooled library for activation of mouse genes

    Depositor

    Feng Zhang

    Available Since

    March 17, 2016

    Availability

    Academic Institutions and Nonprofits only

14. Human Brunello kinome pooled library, guides 1-8 in lentiGuide-Puro backbone

    Pooled Library

    #1000000082

    Purpose

    CRISPR gRNA knockout pooled library for targeting the human kinome

    Depositor

    John Doench, David Root

    Available Since

    June 27, 2016

    Availability

    Academic Institutions and Nonprofits only

15. Sabatini/Lander Lab Activity-Optimized Genome-wide Mouse sgRNA Library in pLenti-sgRNA

    Pooled Library

    #1000000096

    Purpose

    CRISPR gRNA knockout pooled library for targeting the mouse genome

    Depositor

    Eric Lander, David Sabatini

    Available Since

    April 3, 2017

    Availability

    Academic Institutions and Nonprofits only

16. Sabatini/Lander Lab Activity-Optimized Genome-wide Human sgRNA Library in pLenti-sgRNA

    Pooled Library

    #1000000095

    Purpose

    CRISPR gRNA knockout pooled library for targeting the human genome

    Depositor

    Eric Lander, David Sabatini

    Available Since

    April 3, 2017

    Availability

    Academic Institutions and Nonprofits only

17. PCT48

    Pooled Library

    #170392

    Purpose

    Barcoded plasmid library

    Depositor

    Jonathan Weissman

    Article

    Jones et al Genome Biol. 2020 Apr 14;21(1):92. doi:

    Expression

    Mammalian

    Species

    Synthetic

    Use

    CRISPR and Lentiviral

    Available Since

    Nov. 17, 2021

    Availability

    Academic Institutions and Nonprofits only

18. RLC12

    Pooled Library

    #163954

    Purpose

    RLC12 pooled library

    Depositor

    Jeremy Rock

    Article

    Bosch et al Cell. 2021 Jul 16. pii: S0092-8674(21)00

    Expression

    Bacterial

    Use

    CRISPR

    Available Since

    Oct. 1, 2021

    Availability

    Academic Institutions and Nonprofits only

19. RLC11

    Pooled Library

    #163955

    Purpose

    RLC11 pooled library

    Depositor

    Jeremy Rock

    Article

    Bosch et al Cell. 2021 Jul 16. pii: S0092-8674(21)00

    Expression

    Bacterial

    Use

    CRISPR

    Available Since

    Oct. 1, 2021

    Availability

    Academic Institutions and Nonprofits only

20. scCHyMErA-Seq Exon Deletion Library 1

    Pooled Library

    #237473

    Purpose

    The scCHyMErA-Seq Exon Deletion hgRNA Library enables high-throughput identification of frame-preserving exons that influence transcriptional phenotypes, building on the CHyMErA system (Nature Biotechnology, 2020; PMID: 32249828).

    Depositor

    Thomas Gonatopoulos-Pournatzis

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    CRISPR and Lentiviral

    Available Since

    Oct. 28, 2025

    Availability

    Academic Institutions and Nonprofits only