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The Human Druggable CRISPR library

Pooled Library

#200013

Purpose

Knockout library containing ~10,000 sgRNAs targeting 1,980 human druggable genes (5 sgRNAs per gene and 100 non-targeting control sgRNAs).

Depositor

Lianxin Liu

Article

Zheng et al Adv Sci (Weinh). 2023 Aug;10(22):e220679

Expression

Mammalian

Use

CRISPR and Lentiviral

Available Since

May 9, 2023

Availability

Academic Institutions and Nonprofits only
CRISPRi non-coding library (CRiNCL) - Common to all 7 cell lines

Pooled Library

#86538

Depositor

Jonathan Weissman

Article

Liu et al Science. 2017 Jan 06. Vol. 355, Issue 63

Available Since

March 8, 2017

Availability

Academic Institutions and Nonprofits only
Human Transporter Knockout library

Pooled Library

#213695

Purpose

Next generation transporter-focused CRISPR/Cas9 library targeting transmembrane transporters to test the impact of transporters on biological processes.

Depositor

RESOLUTE Consortium, Giulio Superti-Furga

Article

Ferdigg et al Life Sci Alliance. 2024 Nov 22;8(2):e202

Species

Homo sapiens

Use

CRISPR and Lentiviral

Available Since

Sept. 13, 2024

Availability

Academic Institutions and Nonprofits only
SPECS library

Pooled Library

#127842

Purpose

For performing high-throughput cell state-specific synthetic promoter screening

Depositor

Timothy Lu

Article

Wu et al Nat Commun. 2019 Jun 28;10(1):2880. doi:

Species

Synthetic

Use

Lentiviral

Available Since

Aug. 22, 2020

Availability

Academic Institutions and Nonprofits only
Human messenger-RBP sgRNA library

Pooled Library

#168791

Purpose

Knockout library targeting human mRNA binding proteins with 10 sgRNAs/gene.

Depositor

Martin Turner

Article

Turner et al CRISPR J. 2021 Jun;4(3):427-437. doi: 10

Expression

Mammalian

Species

Homo sapiens

Use

CRISPR and Lentiviral

Available Since

July 30, 2021

Availability

Academic Institutions and Nonprofits only
CRISPRi non-coding library (CRiNCL) - Unique to HEK293T

Pooled Library

#86543

Depositor

Jonathan Weissman

Article

Liu et al Science. 2017 Jan 06. Vol. 355, Issue 63

Available Since

March 8, 2017

Availability

Academic Institutions and Nonprofits only
CRISPRi non-coding library (CRiNCL) - iPSC & HFF

Pooled Library

#86550

Depositor

Jonathan Weissman

Article

Liu et al Science. 2017 Jan 06. Vol. 355, Issue 63

Available Since

March 8, 2017

Availability

Academic Institutions and Nonprofits only
CRISPRi non-coding library (CRiNCL) - Unique to K562

Pooled Library

#86544

Depositor

Jonathan Weissman

Article

Liu et al Science. 2017 Jan 06. Vol. 355, Issue 63

Available Since

March 8, 2017

Availability

Academic Institutions and Nonprofits only
CRISPRi non-coding library (CRiNCL) - Unique to HFF

Pooled Library

#86541

Depositor

Jonathan Weissman

Article

Liu et al Science. 2017 Jan 06. Vol. 355, Issue 63

Available Since

March 8, 2017

Availability

Academic Institutions and Nonprofits only
CRISPRi non-coding library (CRiNCL) - Unique to iPSC

Pooled Library

#86540

Depositor

Jonathan Weissman

Article

Liu et al Science. 2017 Jan 06. Vol. 355, Issue 63

Available Since

March 8, 2017

Availability

Academic Institutions and Nonprofits only
CRISPRi non-coding library (CRiNCL) - Unique to U87

Pooled Library

#86542

Depositor

Jonathan Weissman

Article

Liu et al Science. 2017 Jan 06. Vol. 355, Issue 63

Available Since

March 8, 2017

Availability

Academic Institutions and Nonprofits only
CRISPRi non-coding library (CRiNCL) - Unique to MCF7

Pooled Library

#86546

Depositor

Jonathan Weissman

Article

Liu et al Science. 2017 Jan 06. Vol. 355, Issue 63

Available Since

March 8, 2017

Availability

Academic Institutions and Nonprofits only
CRISPRi non-coding library (CRiNCL) - U87 & HEK293T

Pooled Library

#86547

Depositor

Jonathan Weissman

Article

Liu et al Science. 2017 Jan 06. Vol. 355, Issue 63

Available Since

March 8, 2017

Availability

Academic Institutions and Nonprofits only
CRISPRi non-coding library (CRiNCL) - K562 & HeLa

Pooled Library

#86549

Depositor

Jonathan Weissman

Article

Liu et al Science. 2017 Jan 06. Vol. 355, Issue 63

Available Since

March 8, 2017

Availability

Academic Institutions and Nonprofits only
CRISPRi non-coding library (CRiNCL) - K562, HeLa, & MCF7

Pooled Library

#86548

Depositor

Jonathan Weissman

Article

Liu et al Science. 2017 Jan 06. Vol. 355, Issue 63

Available Since

March 8, 2017

Availability

Academic Institutions and Nonprofits only
CRISPRi non-coding library (CRiNCL) - Unique to HeLa

Pooled Library

#86545

Depositor

Jonathan Weissman

Article

Liu et al Science. 2017 Jan 06. Vol. 355, Issue 63

Available Since

March 8, 2017

Availability

Academic Institutions and Nonprofits only
Self-targeting epegRNA library, Tiled edits (lRM001)

Pooled Library

#227708

Purpose

CRISPR guide RNA library for prime editing

Depositor

Brittany Adamson

Article

Cirincione et al Nat Methods. 2024 Nov 19. doi: 10.1038/s

Expression

Mammalian

Use

Lentiviral

Available Since

Jan. 23, 2025

Availability

Academic Institutions and Nonprofits only
RNA-binding protein pooled CRISPR knockout library

Pooled Library

#141438

Purpose

Knockout library targeting RNA-binding proteins with 10 guide RNAs per target.

Depositor

Eugene Yeo

Article

Wheeler et al Nat Methods. 2020 May 11. pii: 10.1038/s

Expression

Mammalian

Use

CRISPR and Lentiviral

Available Since

May 28, 2020

Availability

Academic Institutions and Nonprofits only
FNLCR CRISPRa Cell Surface

Pooled Library

#207471

Purpose

CRISPR-based activation library with guide RNAs targeting all cell surface proteins.

Depositor

Raj Chari

Article

Yang et al Sci Adv. 2024 Feb 16;10(7):eadj2445. doi

Expression

Mammalian

Species

Homo sapiens

Use

CRISPR and Lentiviral

Available Since

Jan. 24, 2024

Availability

Academic Institutions and Nonprofits only
Mouse messenger-RBP sgRNA library

Pooled Library

#169082

Purpose

Retroviral knockout library targeting mouse mRNA binding proteins with 10 sgRNAs/gene.

Depositor

Martin Turner

Article

Turner et al eLife. 2022 Apr 22;11. pii: 72313. doi:

Expression

Mammalian

Species

Mus musculus

Use

CRISPR and Lentiviral

Available Since

Sept. 10, 2021

Availability

Academic Institutions and Nonprofits only

Showing: 21 - 40 of 76 results

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More Filters

We narrowed to 76 results for: LAT;

The Human Druggable CRISPR library

CRISPRi non-coding library (CRiNCL) - Common to all 7 cell lines

Human Transporter Knockout library

SPECS library

Human messenger-RBP sgRNA library

CRISPRi non-coding library (CRiNCL) - Unique to HEK293T

CRISPRi non-coding library (CRiNCL) - iPSC & HFF

CRISPRi non-coding library (CRiNCL) - Unique to K562

CRISPRi non-coding library (CRiNCL) - Unique to HFF

CRISPRi non-coding library (CRiNCL) - Unique to iPSC

CRISPRi non-coding library (CRiNCL) - Unique to U87

CRISPRi non-coding library (CRiNCL) - Unique to MCF7

CRISPRi non-coding library (CRiNCL) - U87 & HEK293T

CRISPRi non-coding library (CRiNCL) - K562 & HeLa

CRISPRi non-coding library (CRiNCL) - K562, HeLa, & MCF7

CRISPRi non-coding library (CRiNCL) - Unique to HeLa

Self-targeting epegRNA library, Tiled edits (lRM001)

RNA-binding protein pooled CRISPR knockout library

FNLCR CRISPRa Cell Surface

Mouse messenger-RBP sgRNA library

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