We narrowed to 74 results for: CRISPR-Cas9

#162275

Knockout library targeting a set of human transcription factors for loss-of-function screening.

Chunliang Li

Zhang et al Elife. 2020 Oct 1;9. pii: 57858. doi: 10

Dec. 15, 2020

Academic Institutions and Nonprofits only

#75316

Mouse sgRNA library in backbone lentiGuide-Puro targeting 713 kinase genes and containing 2,852 unique sgRNAs along with 100 non-targeting controls

John Doench, David Root

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

June 27, 2016

Academic Institutions and Nonprofits only

#155200

Hybrid guide RNA library targeting human alternative cassette exons for deletion and disruption

Benjamin Blencowe, Jason Moffat

Gonatopoulos-Pournatzis et al Nat Biotechnol. 2020 May;38(5):638-648.

Sept. 2, 2020

Academic Institutions and Nonprofits only

#155199

Hybrid guide RNA library targetings human paralog pairs and other protein-coding genes.

Benjamin Blencowe, Jason Moffat

Gonatopoulos-Pournatzis et al Nat Biotechnol. 2020 May;38(5):638-648.

Sept. 2, 2020

Academic Institutions and Nonprofits only

#160132

Plasmid library harboring a randomized 8nt PAM 3’ of target site 1. Can be used to profile CRISPR-Cas PAM requirements of enzymes that recognize 3’ PAMs (e.g. Cas9)

Keith Joung, Benjamin Kleinstiver

Walton et al Nat Protoc. 2021 Feb 5. pii: 10.1038/s41

Feb. 8, 2021

Academic Institutions and Nonprofits only

#160133

Plasmid library harboring a randomized 8nt PAM 3’ of target site 2. Can be used to profile CRISPR-Cas PAM requirements of enzymes that recognize 3’ PAMs (e.g. Cas9)

Keith Joung, Benjamin Kleinstiver

Walton et al Nat Protoc. 2021 Feb 5. pii: 10.1038/s41

Feb. 8, 2021

Academic Institutions and Nonprofits only

#213695

Next generation transporter-focused CRISPR/Cas9 library targeting transmembrane transporters to test the impact of transporters on biological processes.

RESOLUTE Consortium, Giulio Superti-Furga

Ferdigg et al Life Sci Alliance. 2024 Nov 22;8(2):e202

Sept. 13, 2024

Academic Institutions and Nonprofits only

#131625

Bacterial inhibition library targeting every small RNA and ORF of the E. coli MG1655 genome. This library has higher inhibition efficiency than the psgRNA library.

David Bikard

Calvo-Villamanan et al Nucleic Acids Res. 2020 Apr 30. pii: 582

May 12, 2020

Academic Institutions and Nonprofits only

#125517

Human CRISPR lentiviral library containing 70,948 guides (4-5 guides/gene) targeting 18,053 human protein-coding genes, in a non-Cas9 containing backbone

Jason Moffat

Mair et al Cell Rep. 2019 Apr 9;27(2):599-615.e12.

Aug. 1, 2019

Academic Institutions and Nonprofits only

#115927

~93,000 gRNAs targeting random positions along the genome of E. coli MG1655 with a NGG PAM motif. Contains ~19 targets per gene and can be used with SpdCas9 to perform pooled CRISPRi screens.

David Bikard

Cui et al Nat Commun. 2018 May 15;9(1):1912. doi:

June 6, 2019

Academic Institutions and Nonprofits only

#180272

Tiles the entire ~154 kb of the BAC16 Kaposi’s Sarcoma-associated Herpes Virus genome. A guide every ~8 bp allows pooled screening of the viral genome.

Britt Glaunsinger

Morgens et al PLoS Pathog. 2022 Jan 18;18(1):e1010236.

Feb. 11, 2022

Academic Institutions and Nonprofits only

#209734

CHyMErA Cas12a Nuclease Optimization hgRNA Libraries allows assessment and comparison of the efficacy of different LbCas12a nucleases in the context of the Cas9-Cas12a CHyMErA system.

Thomas Gonatopoulos-Pournatzis

Xiao et al Mol Cell. 2024 Jul 11;84(13):2553-2572.e

June 20, 2024

Academic Institutions and Nonprofits only

#209735

CHyMErA Cas12a Nuclease Optimization hgRNA Libraries allows assessment and comparison of the efficacy of different AsCas12a nucleases in the context of the Cas9-Cas12a CHyMErA system.

Thomas Gonatopoulos-Pournatzis

Xiao et al Mol Cell. 2024 Jul 11;84(13):2553-2572.e

June 20, 2024

Academic Institutions and Nonprofits only

#90294

Optimized library offering improved accuracy, efficiency, and scalability for CRISPR screens compared to TKOv1

Jason Moffat

Hart et al G3 (Bethesda). 2017 Aug 7;7(8):2719-2727

May 5, 2017

Academic Institutions and Nonprofits only