We narrowed to 5 results for: Lox

1. Mouse Cardiac Transcriptional Regulators CRISPR Knockout Library

   Pooled Library

   #138015

   Purpose

   This library can be used to investigate cardiac gene regulation. It targets transcriptional regulators that are expressed in mouse cardiomyocytes. A subset of GATA4 regulated genes are also included.

   Depositor

   William Pu

   Article

   VanDusen et al bioRxiv 2019, 808402v1; doi: https://doi

   Species

   Mus musculus

   Use

   AAV, CRISPR, and Cre/Lox

   Available since

   April 17, 2020

   Availability

   Academic Institutions and Nonprofits only

2. HR700_TP53Exon5mut

   Pooled Library

   #229137

   Purpose

   Donor vector library to introduce TP53 mutations into the endogenous gene locus at exon 5 of human cells via CRISPR-HDR.

   Depositor

   Thorsten Stiewe

   Article

   Funk et al Nat Genet. 2025 Jan;57(1):140-153. doi:

   Expression

   Mammalian

   Species

   Homo sapiens

   Use

   CRISPR and Cre/Lox

   Available since

   Feb. 24, 2025

   Availability

   Industry, Academic Institutions, and Nonprofits

3. HR700_TP53Exon6mut

   Pooled Library

   #229138

   Purpose

   Donor vector library to introduce TP53 mutations into the endogenous gene locus at exon 6 of human cells via CRISPR-HDR.

   Depositor

   Thorsten Stiewe

   Article

   Funk et al Nat Genet. 2025 Jan;57(1):140-153. doi:

   Expression

   Mammalian

   Species

   Homo sapiens

   Use

   CRISPR and Cre/Lox

   Available since

   Feb. 24, 2025

   Availability

   Industry, Academic Institutions, and Nonprofits

4. HR700_TP53Exon7mut

   Pooled Library

   #229139

   Purpose

   Donor vector library to introduce TP53 mutations into the endogenous gene locus at exon 7 of human cells via CRISPR-HDR.

   Depositor

   Thorsten Stiewe

   Article

   Funk et al Nat Genet. 2025 Jan;57(1):140-153. doi:

   Expression

   Mammalian

   Species

   Homo sapiens

   Use

   CRISPR and Cre/Lox

   Available since

   Feb. 24, 2025

   Availability

   Industry, Academic Institutions, and Nonprofits

5. HR700_TP53Exon8mut

   Pooled Library

   #229140

   Purpose

   Donor vector library to introduce TP53 mutations into the endogenous gene locus at exon 8 of human cells via CRISPR-HDR.

   Depositor

   Thorsten Stiewe

   Article

   Funk et al Nat Genet. 2025 Jan;57(1):140-153. doi:

   Expression

   Mammalian

   Species

   Homo sapiens

   Use

   CRISPR and Cre/Lox

   Available since

   Feb. 24, 2025

   Availability

   Industry, Academic Institutions, and Nonprofits