We narrowed to 8 results for: guide rna expression plasmid

1. Human sgRNA library Brunello in lentiGuide-Puro

   Pooled Library

   #73178

   Purpose

   Human sgRNA library in backbone lentiGuide-Puro targeting 19,114 genes and containing 76,441 unique sgRNAs along with 1000 non-targeting controls

   Depositor

   John Doench, David Root

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Has Service

   Lentiviral Prep

   Expression

   Mammalian

   Use

   CRISPR and Lentiviral

   Available Since

   Feb. 9, 2016

   Availability

   Academic Institutions and Nonprofits only

2. Mouse sgRNA library Brie in lentiGuide-Puro

   Pooled Library

   #73633

   Purpose

   Mouse sgRNA library in backbone lentiGuide-Puro containing 78,637 unique sgRNAs targeting 19,674 genes along with 1000 non-targeting controls

   Depositor

   John Doench, David Root

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Has Service

   Lentiviral Prep

   Expression

   Mammalian

   Use

   CRISPR and Lentiviral

   Available Since

   Feb. 25, 2016

   Availability

   Academic Institutions and Nonprofits only

3. Wei lab paired-guide RNA (pgRNA) CRISPR–Cas9 library for human long non-coding RNAs (lncRNAs)

   Pooled Library

   #89640

   Purpose

   Designed for genomic deletion screening of functional lncRNAs (long non-coding RNAs) using lentiviral pgRNAs (paired-guide RNAs).

   Depositor

   Wensheng Wei

   Article

   Zhu et al Nat Biotechnol. 2016 Dec;34(12):1279-128

   Expression

   Mammalian

   Use

   Lentiviral

   Available Since

   May 17, 2017

   Availability

   Academic Institutions and Nonprofits only

4. CHyMErA Exon-deletion hgRNA Library

   Pooled Library

   #155200

   Purpose

   Hybrid guide RNA library targeting human alternative cassette exons for deletion and disruption

   Depositor

   Benjamin Blencowe, Jason Moffat

   Article

   Gonatopoulos-Pournatzis et al Nat Biotechnol. 2020 May;38(5):638-648.

   Expression

   Mammalian

   Use

   CRISPR and Lentiviral

   Available Since

   Sept. 2, 2020

   Availability

   Academic Institutions and Nonprofits only

5. Mouse Metabolic Gene CRISPRa sgRNA library

   Pooled Library

   #187081

   Purpose

   Library targeting 2,989 mouse metabolic genes for activation of gene expression.

   Depositor

   Kivanc Birsoy

   Article

   Unlu et al Mol Cell. 2022 Aug 4;82(15):2832-2843.e7

   Expression

   Mammalian

   Species

   Mus musculus

   Use

   Lentiviral

   Available Since

   Oct. 26, 2022

   Availability

   Academic Institutions and Nonprofits only

6. Human Metabolic Gene CRISPRa sgRNA library

   Pooled Library

   #187080

   Purpose

   Library targeting 2,989 human metabolic genes for activation of gene expression.

   Depositor

   Kivanc Birsoy

   Article

   Unlu et al Mol Cell. 2022 Aug 4;82(15):2832-2843.e7

   Expression

   Mammalian

   Species

   Homo sapiens

   Use

   Lentiviral

   Available Since

   Oct. 26, 2022

   Availability

   Academic Institutions and Nonprofits only

7. CHyMErA Paralog&Dual-targeting hgRNA Library

   Pooled Library

   #155199

   Purpose

   Hybrid guide RNA library targetings human paralog pairs and other protein-coding genes.

   Depositor

   Benjamin Blencowe, Jason Moffat

   Article

   Gonatopoulos-Pournatzis et al Nat Biotechnol. 2020 May;38(5):638-648.

   Expression

   Mammalian

   Use

   CRISPR and Lentiviral

   Available Since

   Sept. 2, 2020

   Availability

   Academic Institutions and Nonprofits only

8. Human Paralog Knockout Library (pgPEN)

   Pooled Library

   #171172

   Purpose

   Induces knockouts of paralogous gene pairs. Plasmids express a pair of guide RNAs targeting either individual genes or a pair of paralogs.

   Depositor

   Alice Berger

   Article

   Parrish et al Cell Rep. 2021 Aug 31;36(9):109597. doi:

   Expression

   Mammalian

   Species

   Homo sapiens and Synthetic

   Use

   CRISPR and Lentiviral

   Available Since

   Sept. 28, 2021

   Availability

   Academic Institutions and Nonprofits only