We narrowed to 18 results for: otos

1. Human Kinase Domain-Focused CRISPR Knockout Library

   Pooled Library

   #117725

   Purpose

   gRNAs targeting the kinase domain of human protein kinases

   Depositor

   Christopher Vakoc

   Article

   Tarumoto et al Mol Cell. 2018 Feb 28. pii: S1097-2765(1

   Expression

   Mammalian

   Species

   Homo sapiens

   Use

   CRISPR and Lentiviral

   Available since

   Jan. 4, 2019

   Availability

   Academic Institutions and Nonprofits only

2. pSMAL-CellTag-V1

   Pooled Library

   #115643

   Purpose

   Viral barcoding library to combinatorially index cells for single-cell analysis of clonal dynamics

   Depositor

   Samantha Morris

   Article

   Biddy et al Nature. 2018 Dec;564(7735):219-224. doi:

   Has Service

   Concentrated Lentiviral Prep

   Expression

   Mammalian

   Species

   Synthetic

   Use

   Lentiviral

   Available since

   Dec. 5, 2018

   Availability

   Academic Institutions and Nonprofits only

3. pSMAL-CellTag-V2

   Pooled Library

   #115644

   Purpose

   Viral barcoding library to combinatorially index cells for single-cell analysis of clonal dynamics

   Depositor

   Samantha Morris

   Article

   Biddy et al Nature. 2018 Dec;564(7735):219-224. doi:

   Has Service

   Concentrated Lentiviral Prep

   Expression

   Mammalian

   Species

   Synthetic

   Use

   Lentiviral

   Available since

   Dec. 5, 2018

   Availability

   Academic Institutions and Nonprofits only

4. pSMAL-CellTag-V3

   Pooled Library

   #115645

   Purpose

   Viral barcoding library to combinatorially index cells for single-cell analysis of clonal dynamics

   Depositor

   Samantha Morris

   Article

   Biddy et al Nature. 2018 Dec;564(7735):219-224. doi:

   Has Service

   Concentrated Lentiviral Prep

   Expression

   Mammalian

   Species

   Synthetic

   Use

   Lentiviral

   Available since

   Dec. 5, 2018

   Availability

   Academic Institutions and Nonprofits only

5. Mouse Metabolism Library

   Pooled Library

   #163966

   Purpose

   Lentiviral CRISPR library targets 2,918 mouse metabolic genes with ~18,000 guide RNAs. The library contains ~6 gRNAs per gene.

   Depositor

   Alec Kimmelman

   Article

   Biancur et al Cell Metab. 2020 Oct 28. pii: S1550-4131

   Use

   CRISPR and Lentiviral

   Available since

   July 1, 2021

   Availability

   Academic Institutions and Nonprofits only

6. p11-3’_8xN_PAM-site1 (RTW554)

   Pooled Library

   #160132

   Purpose

   Plasmid library harboring a randomized 8nt PAM 3’ of target site 1. Can be used to profile CRISPR-Cas PAM requirements of enzymes that recognize 3’ PAMs (e.g. Cas9)

   Depositor

   Benjamin Kleinstiver, Keith Joung

   Article

   Walton et al Nat Protoc. 2021 Feb 5. pii: 10.1038/s41

   Species

   Synthetic

   Use

   CRISPR

   Available since

   Feb. 8, 2021

   Availability

   Academic Institutions and Nonprofits only

7. p11-5’_10xN_PAM-site4 (RTW574)

   Pooled Library

   #160135

   Purpose

   Plasmid library harboring a randomized 10nt PAM 5’ of target site 4. Can be used to profile CRISPR-Cas PAM requirements of enzymes that recognize 5’ PAMs (e.g. Cas12a)

   Depositor

   Benjamin Kleinstiver, Keith Joung

   Article

   Walton et al Nat Protoc. 2021 Feb 5. pii: 10.1038/s41

   Species

   Synthetic

   Use

   CRISPR

   Available since

   Feb. 8, 2021

   Availability

   Academic Institutions and Nonprofits only

8. p11-3’_8xN_PAM-site2 (RTW555)

   Pooled Library

   #160133

   Purpose

   Plasmid library harboring a randomized 8nt PAM 3’ of target site 2. Can be used to profile CRISPR-Cas PAM requirements of enzymes that recognize 3’ PAMs (e.g. Cas9)

   Depositor

   Benjamin Kleinstiver, Keith Joung

   Article

   Walton et al Nat Protoc. 2021 Feb 5. pii: 10.1038/s41

   Species

   Synthetic

   Use

   CRISPR

   Available since

   Feb. 8, 2021

   Availability

   Academic Institutions and Nonprofits only

9. pSMAL-CellTag-multi-v1 barcode library

   Pooled Library

   #206045

   Purpose

   The CellTag multi library of barcodes can be used to clonally label cells with DNA barcodes. These barcodes can be profiled directly with single-cell RNA and ATAC sequencing, to allow clonal tracking

   Depositor

   Samantha Morris

   Article

   Jindal et al Nat Biotechnol. 2023 Sep 25. doi: 10.103

   Use

   Lentiviral

   Available since

   Nov. 2, 2023

   Availability

   Academic Institutions and Nonprofits only

10. Human SLC KO Library

    Pooled Library

    #132552

    Purpose

    Expresses gRNAs for knockout of the human Solute Carrier family

    Depositor

    Giulio Superti-Furga

    Article

    Girardi et al Nat Chem Biol. 2020 Apr;16(4):469-478. d

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    CRISPR and Lentiviral

    Available since

    May 7, 2020

    Availability

    Academic Institutions and Nonprofits only

11. plIG-123_HA-GD2-28z_CAR_TF_Library

    Pooled Library

    #207478

    Purpose

    HA-GD2-28z CAR in combination with 100 transcription factors (and related proteins) and 2 controls (GFP/RFP). Library can be used to generate HDR templates for modular pooled knockin (ModPoKI) into th

    Depositor

    Alexander Marson

    Article

    Blaeschke et al Cell. 2023 Sep 14;186(19):4216-4234.e33.

    Species

    Homo sapiens

    Use

    CRISPR

    Available since

    Jan. 26, 2024

    Availability

    Academic Institutions and Nonprofits only

12. plIG-128_HA-GD2-28z_CAR_TFxTF_Library

    Pooled Library

    #207480

    Purpose

    HA-GD2-28z CAR in combination with ~10,000 transcription factor combinations (and related proteins) and controls (GFP/RFP combinations). Library can be used to generate HDR templates for modular poole

    Depositor

    Alexander Marson

    Article

    Blaeschke et al Cell. 2023 Sep 14;186(19):4216-4234.e33.

    Use

    CRISPR

    Available since

    Jan. 26, 2024

    Availability

    Academic Institutions and Nonprofits only

13. plIG-106_NY-ESO-1_TCR_SR_Library

    Pooled Library

    #207474

    Purpose

    NY-ESO-1 TCR in combination with 129 surface receptors and 2 controls (GFP/RFP). Library can be used to generate HDR templates for modular pooled knockin (ModPoKI) into the TRAC locus of human T cells

    Depositor

    Alexander Marson

    Article

    Blaeschke et al Cell. 2023 Sep 14;186(19):4216-4234.e33.

    Species

    Homo sapiens

    Use

    CRISPR

    Available since

    Jan. 26, 2024

    Availability

    Academic Institutions and Nonprofits only

14. plIG-107_NY-ESO-1_TCR_TF_Library

    Pooled Library

    #207475

    Purpose

    NY-ESO-1 TCR in combination with 100 transcription factors (and related proteins) and 2 controls (GFP/RFP). Library can be used to generate HDR templates for modular pooled knockin (ModPoKI) into the

    Depositor

    Alexander Marson

    Article

    Blaeschke et al Cell. 2023 Sep 14;186(19):4216-4234.e33.

    Species

    Homo sapiens

    Use

    CRISPR

    Available since

    Jan. 26, 2024

    Availability

    Academic Institutions and Nonprofits only

15. plIG-109_CD19-BBz_CAR_SR_Library

    Pooled Library

    #207476

    Purpose

    CD19-BBz CAR in combination with 129 surface receptors and 2 controls (GFP/RFP). Library can be used to generate HDR templates for modular pooled knockin (ModPoKI) into the TRAC locus of human T cells

    Depositor

    Alexander Marson

    Article

    Blaeschke et al Cell. 2023 Sep 14;186(19):4216-4234.e33.

    Use

    CRISPR

    Available since

    Jan. 26, 2024

    Availability

    Academic Institutions and Nonprofits only

16. plIG-110_CD19-BBz_CAR_TF_Library

    Pooled Library

    #207477

    Purpose

    CD19-BBz CAR in combination with 100 transcription factors (and related proteins) and 2 controls (GFP/RFP). Library can be used to generate HDR templates for modular pooled knockin (ModPoKI) into the

    Depositor

    Alexander Marson

    Article

    Blaeschke et al Cell. 2023 Sep 14;186(19):4216-4234.e33.

    Species

    Homo sapiens

    Use

    CRISPR

    Available since

    Jan. 26, 2024

    Availability

    Academic Institutions and Nonprofits only

17. plIG-124_HA-GD2-28z_CAR_SR_Library

    Pooled Library

    #207479

    Purpose

    HA-GD2-28z CAR in combination with 129 surface receptors and 2 controls (GFP/RFP). Library can be used to generate HDR templates for modular pooled knockin (ModPoKI) into the TRAC locus of human T cel

    Depositor

    Alexander Marson

    Article

    Blaeschke et al Cell. 2023 Sep 14;186(19):4216-4234.e33.

    Species

    Homo sapiens

    Use

    CRISPR

    Available since

    Jan. 26, 2024

    Availability

    Academic Institutions and Nonprofits only

18. plIG-132_CD19-28z_CAR_TF_and_SR_Library

    Pooled Library

    #207481

    Purpose

    CD19-28z CAR in combination with 129 surface receptors, 100 transcription factors (and related proteins) and 2 controls (GFP/RFP). Library can be used to generate HDR templates for modular pooled knoc

    Depositor

    Alexander Marson

    Article

    Blaeschke et al Cell. 2023 Sep 14;186(19):4216-4234.e33.

    Species

    Homo sapiens

    Use

    CRISPR

    Available since

    Jan. 26, 2024

    Availability

    Academic Institutions and Nonprofits only