We narrowed to 9 results for: rela

1. Human ubiquitination-related proteins CRISPR KO library

   Pooled Library

   #174592

   Purpose

   CRISPR Cas9 KO library targets 660 ubiquitination-related proteins, including all major E1, E2, E3 and deubiquitinating enzymes, as well as other ubiquitination-related proteins.

   Depositor

   Juan Bonifacino

   Article

   Jia et al Elife. 2019 Nov 6;8. pii: 50034. doi: 10

   Expression

   Mammalian

   Species

   Homo sapiens

   Use

   CRISPR and Lentiviral

   Available since

   Nov. 30, 2021

   Availability

   Academic Institutions and Nonprofits only

2. Human Lentiviral sgRNA Library - Cell Cycle

   Pooled Library

   #51046

   Purpose

   Sub-pool of Sabatini/Lander sgRNA library enriched for cell cycle-related targets.

   Depositor

   Eric Lander, David Sabatini

   Article

   Wang et al Science. 2014 Jan 3;343(6166):80-4. doi:

   Expression

   Mammalian

   Species

   Homo sapiens

   Use

   CRISPR and Lentiviral

   Available since

   Feb. 7, 2014

   Availability

   Academic Institutions and Nonprofits only

3. Human Lipid Droplet and Metabolism Library

   Pooled Library

   #191535

   Purpose

   Lentiviral CRISPR library targeting 1,196 genes related to lipid droplet biology and cell metabolism.

   Depositor

   James Olzmann

   Article

   Roberts et al Dev Cell. 2023 Jul 18:S1534-5807(23)0033

   Expression

   Mammalian

   Use

   CRISPR and Lentiviral

   Available since

   March 1, 2023

   Availability

   Academic Institutions and Nonprofits only

4. Pan-Druggable Cancer Library

   Pooled Library

   #182133

   Purpose

   All-in-one CRISPR/Cas system with 74 individual elements. 63 elements target cancer-related genes with FDA-approved drug treatments, and 3 elements target key medulloblastoma driver genes.

   Depositor

   Prashant Mali

   Article

   Hu et al Biomaterials. 2022 Jan;280:121276. doi:

   Species

   Homo sapiens

   Use

   CRISPR and Lentiviral

   Available since

   Aug. 26, 2022

   Availability

   Academic Institutions and Nonprofits only

5. plIG-123_HA-GD2-28z_CAR_TF_Library

   Pooled Library

   #207478

   Purpose

   HA-GD2-28z CAR in combination with 100 transcription factors (and related proteins) and 2 controls (GFP/RFP). Library can be used to generate HDR templates for modular pooled knockin (ModPoKI) into th

   Depositor

   Alexander Marson

   Article

   Blaeschke et al Cell. 2023 Sep 14;186(19):4216-4234.e33.

   Species

   Homo sapiens

   Use

   CRISPR

   Available since

   Jan. 26, 2024

   Availability

   Academic Institutions and Nonprofits only

6. plIG-128_HA-GD2-28z_CAR_TFxTF_Library

   Pooled Library

   #207480

   Purpose

   HA-GD2-28z CAR in combination with ~10,000 transcription factor combinations (and related proteins) and controls (GFP/RFP combinations). Library can be used to generate HDR templates for modular poole

   Depositor

   Alexander Marson

   Article

   Blaeschke et al Cell. 2023 Sep 14;186(19):4216-4234.e33.

   Use

   CRISPR

   Available since

   Jan. 26, 2024

   Availability

   Academic Institutions and Nonprofits only

7. plIG-107_NY-ESO-1_TCR_TF_Library

   Pooled Library

   #207475

   Purpose

   NY-ESO-1 TCR in combination with 100 transcription factors (and related proteins) and 2 controls (GFP/RFP). Library can be used to generate HDR templates for modular pooled knockin (ModPoKI) into the

   Depositor

   Alexander Marson

   Article

   Blaeschke et al Cell. 2023 Sep 14;186(19):4216-4234.e33.

   Species

   Homo sapiens

   Use

   CRISPR

   Available since

   Jan. 26, 2024

   Availability

   Academic Institutions and Nonprofits only

8. plIG-110_CD19-BBz_CAR_TF_Library

   Pooled Library

   #207477

   Purpose

   CD19-BBz CAR in combination with 100 transcription factors (and related proteins) and 2 controls (GFP/RFP). Library can be used to generate HDR templates for modular pooled knockin (ModPoKI) into the

   Depositor

   Alexander Marson

   Article

   Blaeschke et al Cell. 2023 Sep 14;186(19):4216-4234.e33.

   Species

   Homo sapiens

   Use

   CRISPR

   Available since

   Jan. 26, 2024

   Availability

   Academic Institutions and Nonprofits only

9. plIG-132_CD19-28z_CAR_TF_and_SR_Library

   Pooled Library

   #207481

   Purpose

   CD19-28z CAR in combination with 129 surface receptors, 100 transcription factors (and related proteins) and 2 controls (GFP/RFP). Library can be used to generate HDR templates for modular pooled knoc

   Depositor

   Alexander Marson

   Article

   Blaeschke et al Cell. 2023 Sep 14;186(19):4216-4234.e33.

   Species

   Homo sapiens

   Use

   CRISPR

   Available since

   Jan. 26, 2024

   Availability

   Academic Institutions and Nonprofits only