1,050 results

1. pAAV-Ef1a-sRGECO (AAV8)

   Viral Prep

   #137125-AAV8

   Purpose

   Ready-to-use AAV8 particles produced from pAAV-Ef1a-sRGECO (#137125). In addition to the viral particles, you will also receive purified pAAV-Ef1a-sRGECO plasmid DNA. EF1a-driven expression of cytosolic sRGECO calcium sensor. These AAV preparations are suitable purity for injection into animals.

   Depositor

   Karl Deisseroth, INTRSECT 2.0 Project

   Article

   Fenno et al Neuron. 2020 Jun 20. pii: S0896-6273(20)

   Promoter

   EF1a

   Available Since

   May 6, 2021

   Availability

   Academic Institutions and Nonprofits only

2. pZac2.1-GfaABC1D-lck-jGCaMP8f (AAV1)

   Viral Prep

   #176759-AAV1

   Purpose

   Ready-to-use AAV1 particles produced from pZac2.1-GfaABC1D-lck-jGCaMP8f (#176759). In addition to the viral particles, you will also receive purified pZac2.1-GfaABC1D-lck-jGCaMP8f plasmid DNA. GfaABC1D-driven expression of membrane-bound calcium sensor GCaMP8f. These AAV preparations are suitable purity for injection into animals.

   Depositor

   Loren Looger

   Promoter

   GfaABC1D

   Available Since

   July 12, 2023

   Availability

   Academic Institutions and Nonprofits only

3. pGP-AAV-syn-flex-iGABASnFR2-WPRE (AAV5)

   Viral Prep

   #218877-AAV5

   Purpose

   Ready-to-use AAV5 particles produced from pGP-AAV-syn-flex-iGABASnFR2-WPRE (#218877). In addition to the viral particles, you will also receive purified pGP-AAV-syn-flex-iGABASnFR2-WPRE plasmid DNA. Syn-driven, Cre-dependent expression of the improved GABA sensor iGABASnFR2 (positive change in fluorescence). These AAV preparations are suitable purity for injection into animals.

   Depositor

   GENIE Project

   Article

   Kolb et al bioRxiv 2025.03.25.644953

   Promoter

   Syn

   Available Since

   Sept. 27, 2024

   Availability

   Academic Institutions and Nonprofits only

4. pAAV.hSyn.FLEX.iGluSnFR3.v857.PDGFR.codonopt (AAV1)

   Viral Prep

   #175180-AAV1

   Purpose

   Ready-to-use AAV1 particles produced from pAAV.hSyn.FLEX.iGluSnFR3.v857.PDGFR.codonopt (#175180). In addition to the viral particles, you will also receive purified pAAV.hSyn.FLEX.iGluSnFR3.v857.PDGFR.codonopt plasmid DNA. Synapsin-driven, Cre-dependent, iGluSnFR3 glutamate sensor. These AAV preparations are suitable purity for injection into animals.

   Depositor

   Kaspar Podgorski

   Article

   Aggarwal et al Nat Methods. 2023 May 4. doi: 10.1038/s4

   Promoter

   Syn

   Available Since

   July 1, 2022

   Availability

   Academic Institutions and Nonprofits only

5. pAAV-Ef1a-fDIO EYFP (AAV2)

   Viral Prep

   #55641-AAV2

   Purpose

   Ready-to-use AAV2 particles produced from pAAV-Ef1a-fDIO EYFP (#55641). In addition to the viral particles, you will also receive purified pAAV-Ef1a-fDIO EYFP plasmid DNA. EF1a-driven, Flp-dependent expression of EYFP. These AAV preparations are suitable purity for injection into animals.

   Depositor

   Karl Deisseroth

   Article

   Fenno et al Nat Methods. 2014 Jul;11(7):763-72. doi:

   Promoter

   EF1a

   Tags

   EYFP (Flp-dependent)

   Available Since

   Sept. 27, 2023

   Availability

   Academic Institutions and Nonprofits only

6. pAAV-mDlx-GFP-Fishell-1 (AAV5)

   Viral Prep

   #83900-AAV5

   Purpose

   Ready-to-use AAV5 particles produced from pAAV-mDlx-GFP-Fishell-1 (#83900). In addition to the viral particles, you will also receive purified pAAV-mDlx-GFP-Fishell-1 plasmid DNA. mDlx-driven expression of GFP in GABA-ergic interneurons. These AAV preparations are suitable purity for injection into animals.

   Depositor

   Gordon Fishell

   Article

   Dimidschstein et al Nat Neurosci. 2016 Oct 31. doi: 10.1038/

   Promoter

   mDlx

   Tags

   GFP

   Available Since

   Aug. 25, 2023

   Availability

   Academic Institutions and Nonprofits only

7. pAAV-hSyn-EGFP (AAV5 trial size)

   Viral Prep

   #50465-AAV5.T

   Purpose

   Ready-to-use AAV5 trial size particles produced from pAAV-hSyn-EGFP (#50465). In addition to the viral particles, you will also receive purified pAAV-hSyn-EGFP plasmid DNA. hSyn-driven EGFP expression. These AAV preparations are suitable purity for injection into animals.

   Depositor

   Bryan Roth

   Promoter

   Syn

   Tags

   EGFP

   Available Since

   June 12, 2019

   Availability

   Academic Institutions and Nonprofits only

8. pAAV-CaMKIIa-hM3D(Gq)-mCherry (AAV2)

   Viral Prep

   #50476-AAV2

   Purpose

   Ready-to-use AAV2 particles produced from pAAV-CaMKIIa-hM3D(Gq)-mCherry (#50476). In addition to the viral particles, you will also receive purified pAAV-CaMKIIa-hM3D(Gq)-mCherry plasmid DNA. CaMKIIa-driven hM3D(Gq) receptor with an mCherry reporter for CNO-induced neuronal activation. These AAV preparations are suitable purity for injection into animals.

   Depositor

   Bryan Roth

   Promoter

   CaMKII

   Tags

   mCherry

   Available Since

   Jan. 26, 2021

   Availability

   Academic Institutions and Nonprofits only

9. pAAV.CAG.hChR2(H134R)-mCherry.WPRE.SV40 (AAV2)

   Viral Prep

   #100054-AAV2

   Purpose

   Ready-to-use AAV2 particles produced from pAAV.CAG.hChR2(H134R)-mCherry.WPRE.SV40 (#100054). In addition to the viral particles, you will also receive purified pAAV.CAG.hChR2(H134R)-mCherry.WPRE.SV40 plasmid DNA. CAG-driven, humanized channelrhodopsin H134R mutant fused to mCherry for optogenetic activation. These AAV preparations are suitable purity for injection into animals.

   Depositor

   Karl Deisseroth

   Promoter

   CAG

   Tags

   mCherry

   Available Since

   Oct. 7, 2020

   Availability

   Academic Institutions and Nonprofits only

10. AiP14035: pAAV-AiE0452h_3xC2-minBG-CoChR-EGFP-WPRE3-BGHpA (Alias: CN4035) (AAV PHP.eB)

    Viral Prep

    #214853-PHPeB

    Purpose

    Ready-to-use AAV PHP.eB particles produced from AiP14035: pAAV-AiE0452h_3xC2-minBG-CoChR-EGFP-WPRE3-BGHpA (Alias: CN4035) (#214853). In addition to the viral particles, you will also receive purified AiP14035: pAAV-AiE0452h_3xC2-minBG-CoChR-EGFP-WPRE3-BGHpA (Alias: CN4035) plasmid DNA. minBG-driven expression of CoChR-EGFP striatal indirect pathway medium spiny neurons (D2 MSNs). These AAV were produced with the PHPeB serotype, which permits efficient transduction of the central nervous system. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Jonathan Ting, Allen Institute for Brain Science

    Article

    Hunker et al Neuron. 2025 May 21;113(10):1507-1524.e1

    Tags

    EGFP

    Available Since

    Nov. 13, 2024

    Availability

    Academic Institutions and Nonprofits only

11. pAAV_BiLAMP5e3_dTomato_nlsdTomato (AAV PHP.eB)

    Viral Prep

    #218792-PHPeB

    Purpose

    Ready-to-use AAV PHP.eB particles produced from pAAV_BiLAMP5e3_dTomato_nlsdTomato (#218792). In addition to the viral particles, you will also receive purified pAAV_BiLAMP5e3_dTomato_nlsdTomato plasmid DNA. Bicistronic expression of dTomato and nuclear-targeted dTomato under the control of the Lamp5 interneuron-targeting enhancer. These AAV were produced with the PHPeB serotype, which permits efficient transduction of the central nervous system. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Gordon Fishell

    Article

    Furlanis et al Neuron. 2025 May 21;113(10):1525-1547.e1

    Available Since

    Sept. 23, 2025

    Availability

    Academic Institutions and Nonprofits only

12. pAAV-nEF-Con/Foff DREADD Gi-mCherry (AAV8)

    Viral Prep

    #177673-AAV8

    Purpose

    Ready-to-use AAV8 particles produced from pAAV-nEF-Con/Foff DREADD Gi-mCherry (#177673). In addition to the viral particles, you will also receive purified pAAV-nEF-Con/Foff DREADD Gi-mCherry plasmid DNA. nEF-driven hM4D(Gi) receptor with an mCherry reporter for CNO-induced neuronal inhibition only in Cre expressing cells and not in Flp expressing cells. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Karl Deisseroth

    Promoter

    nEF

    Tags

    mCherry

    Available Since

    Feb. 16, 2024

    Availability

    Academic Institutions and Nonprofits only

13. pAAV-FLEX-EGFPL10a (AAV Retrograde)

    Viral Prep

    #98747-AAVrg

    Purpose

    Ready-to-use AAV Retrograde particles produced from pAAV-FLEX-EGFPL10a (#98747). In addition to the viral particles, you will also receive purified pAAV-FLEX-EGFPL10a plasmid DNA. Cre-dependent EGFPL10a (EGFP-tagged ribosomal protein) expression for translating ribosome affinity purification (TRAP). These AAV were produced with a retrograde serotype, which permits retrograde access to projection neurons. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Alexander Nectow, Eric Schmidt, Nathaniel Heintz

    Article

    Nectow et al Cell Rep. 2017 Apr 18;19(3):655-667. doi

    Promoter

    EF1a

    Tags

    EGFP (Cre-dependent)

    Available Since

    Sept. 27, 2023

    Availability

    Academic Institutions and Nonprofits only

14. pAAV-CAG-FLEX-rc [Jaws-KGC-GFP-ER2] (AAV Retrograde)

    Viral Prep

    #84445-AAVrg

    Purpose

    Ready-to-use AAV Retrograde particles produced from pAAV-CAG-FLEX-rc [Jaws-KGC-GFP-ER2] (#84445). In addition to the viral particles, you will also receive purified pAAV-CAG-FLEX-rc [Jaws-KGC-GFP-ER2] plasmid DNA. CAG-drive, Cre-dependent Jaws-GFP for optogenetic inhibition. These AAV were produced with a retrograde serotype, which permits retrograde access to projection neurons. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Edward Boyden

    Article

    Chuong et al Nat Neurosci. 2014 Aug;17(8):1123-9. doi

    Promoter

    CAG

    Tags

    GFP (Cre-dependent)

    Available Since

    Oct. 12, 2017

    Availability

    Academic Institutions and Nonprofits only

15. pAAV-Ef1a-Con/Foff 2.0-GCaMP6M (AAV8)

    Viral Prep

    #137120-AAV8

    Purpose

    Ready-to-use AAV8 particles produced from pAAV-Ef1a-Con/Foff 2.0-GCaMP6M (#137120). In addition to the viral particles, you will also receive purified pAAV-Ef1a-Con/Foff 2.0-GCaMP6M plasmid DNA. EF1a-driven expression of GCaMP6m in the presence of Cre recombinase (inhibited in the presence of Flp recombinase). These AAV preparations are suitable purity for injection into animals.

    Depositor

    Karl Deisseroth, INTRSECT 2.0 Project

    Article

    Fenno et al Neuron. 2020 Jun 20. pii: S0896-6273(20)

    Promoter

    EF1a

    Available Since

    Nov. 23, 2020

    Availability

    Academic Institutions and Nonprofits only

16. pAAV-CAG-GFP (AAV CAP-B10)

    Viral Prep

    #37825-CAP-B10

    Purpose

    Ready-to-use AAV CAP-B10 particles produced from pAAV-CAG-GFP (#37825). In addition to the viral particles, you will also receive purified pAAV-CAG-GFP plasmid DNA. CAG-driven GFP expression. These AAV were produced with the CAP-B10 serotype, which permits efficient transduction of both inhibitory and excitatory neurons in the central nervous system. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Edward Boyden

    Promoter

    CAG

    Tags

    GFP

    Available Since

    Nov. 8, 2023

    Availability

    Academic Institutions and Nonprofits only

17. pAAV.CAGFLEX.(cyto).iATPSnFR2.S29W.A95K.HaloTag (AAV5)

    Viral Prep

    #209655-AAV5

    Purpose

    Ready-to-use AAV5 particles produced from pAAV.CAGFLEX.(cyto).iATPSnFR2.S29W.A95K.HaloTag (#209655). In addition to the viral particles, you will also receive purified pAAV.CAGFLEX.(cyto).iATPSnFR2.S29W.A95K.HaloTag plasmid DNA. CAG-driven, Cre-dependent expression of the high affinity ATP biosensor iATPSnFR2. These AAV preparations are suitable purity for injection into animals.

    Depositor

    HHMI-JRC Tool Translation Team, Tim Brown

    Article

    Marvin et al Proc Natl Acad Sci U S A. 2024 May 21;12

    Promoter

    CAG

    Available Since

    Oct. 21, 2024

    Availability

    Academic Institutions and Nonprofits only

18. pAAV_BiCHATe27_dTomato_nlsdTomato (AAV1)

    Viral Prep

    #213829-AAV1

    Purpose

    Ready-to-use AAV1 particles produced from pAAV_BiCHATe27_dTomato_nlsdTomato (#213829). In addition to the viral particles, you will also receive purified pAAV_BiCHATe27_dTomato_nlsdTomato plasmid DNA. Bicistronic expression of dTomato and nuclear-targeted dTomato under the control of the cholinergic neuron-targeting enhancer E27. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Gordon Fishell

    Article

    Furlanis et al Neuron. 2025 May 21;113(10):1525-1547.e1

    Tags

    dTomato

    Available Since

    Sept. 23, 2025

    Availability

    Academic Institutions and Nonprofits only

19. pAAV-Ef1a-DIO-PPO-Venus (AAV8)

    Viral Prep

    #139505-AAV8

    Purpose

    Ready-to-use AAV8 particles produced from pAAV-Ef1a-DIO-PPO-Venus (#139505). In addition to the viral particles, you will also receive purified pAAV-Ef1a-DIO-PPO-Venus plasmid DNA. EF1a-driven, Cre-dependent expression of Venus-tagged parapinopsin for spatiotemporal control of inhibitory GPCR signaling cascades. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Michael Bruchas

    Article

    Copits et al Neuron. 2021 Jun 2;109(11):1791-1809.e11

    Promoter

    EF1a

    Tags

    Venus (Cre-dependent)

    Available Since

    Sept. 27, 2023

    Availability

    Academic Institutions and Nonprofits only

20. pAAV-nEF-Con/Fon-NpHR3.3-EYFP (AAV8)

    Viral Prep

    #137152-AAV8

    Purpose

    Ready-to-use AAV8 particles produced from pAAV-nEF-Con/Fon-NpHR3.3-EYFP (#137152). In addition to the viral particles, you will also receive purified pAAV-nEF-Con/Fon-NpHR3.3-EYFP plasmid DNA. nEF-driven, Cre and Flp-dependent expression of NpHR3.3-EYFP for optogenetic inhibition. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Karl Deisseroth, INTRSECT 2.0 Project

    Article

    Fenno et al Neuron. 2020 Jun 20. pii: S0896-6273(20)

    Promoter

    nEF

    Tags

    EYFP (Cre and Flp-dependent)

    Available Since

    Feb. 25, 2021

    Availability

    Academic Institutions and Nonprofits only

21. pAAV-Syn-Chronos-GFP (AAV Retrograde)

    Viral Prep

    #59170-AAVrg

    Purpose

    Ready-to-use AAV Retrograde particles produced from pAAV-Syn-Chronos-GFP (#59170). In addition to the viral particles, you will also receive purified pAAV-Syn-Chronos-GFP plasmid DNA. Chronos-GFP under the control of the Synapsin promoter. These AAV were produced with a retrograde serotype, which permits retrograde access to projection neurons. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Edward Boyden

    Article

    Klapoetke et al Nat Methods. 2014 Mar;11(3):338-46. doi:

    Promoter

    Syn

    Tags

    GFP

    Available Since

    Oct. 3, 2017

    Availability

    Academic Institutions and Nonprofits only

22. pAAV.hSynap-FLEX.SF-iGluSnFR.A184S (AAV5)

    Viral Prep

    #106180-AAV5

    Purpose

    Ready-to-use AAV5 particles produced from pAAV.hSynap-FLEX.SF-iGluSnFR.A184S (#106180). In addition to the viral particles, you will also receive purified pAAV.hSynap-FLEX.SF-iGluSnFR.A184S plasmid DNA. Synapsin-driven, Cre-dependent expression of glutamate sensor iGluSnFR (high affinity). These AAV preparations are suitable purity for injection into animals.

    Depositor

    Loren Looger

    Article

    Marvin et al Nat Methods. 2018 Nov;15(11):936-939. do

    Promoter

    Syn

    Available Since

    March 19, 2021

    Availability

    Academic Institutions and Nonprofits only

23. pAAV_hSyn-DIO-PdCO-mScarlet-WPRE (AAV5)

    Viral Prep

    #198511-AAV5

    Purpose

    Ready-to-use AAV5 particles produced from pAAV_hSyn-DIO-PdCO-mScarlet-WPRE (#198511). In addition to the viral particles, you will also receive purified pAAV_hSyn-DIO-PdCO-mScarlet-WPRE plasmid DNA. Syn-driven Cre-dependent expression of optimized PdCO in frame with mScarlet. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Ofer Yizhar

    Article

    Wietek et al Nat Methods. 2024 May 29. doi: 10.1038/s

    Promoter

    Syn

    Tags

    mScarlet (Cre-dependent)

    Available Since

    Sept. 27, 2024

    Availability

    Academic Institutions and Nonprofits only

24. pAAV-hsyn-NE2h (AAV5)

    Viral Prep

    #208687-AAV5

    Purpose

    Ready-to-use AAV5 particles produced from pAAV-hsyn-NE2h (#208687). In addition to the viral particles, you will also receive purified pAAV-hsyn-NE2h plasmid DNA. Synapsin-driven expression of genetically-encoded fluorescent norepinephrine (NE) sensor GRAB_NE2h. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Yulong Li

    Article

    Feng et al Neuron. 2024 Jun 19;112(12):1930-1942.e6

    Promoter

    Syn

    Available Since

    Aug. 7, 2025

    Availability

    Academic Institutions and Nonprofits only

25. pAAV-S5E2-GFP-fGFP (AAV9)

    Viral Prep

    #135631-AAV9

    Purpose

    Ready-to-use AAV9 particles produced from pAAV-S5E2-GFP-fGFP (#135631). In addition to the viral particles, you will also receive purified pAAV-S5E2-GFP-fGFP plasmid DNA. Bicistronic expression of GFP and membrane-targeted GFP under the control of the E2 regulatory element. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Jordane Dimidschstein

    Article

    Vormstein-Schneider et al Nat Neurosci. 2020 Dec;23(12):1629-1636.

    Tags

    EGFP

    Available Since

    Sept. 27, 2023

    Availability

    Academic Institutions and Nonprofits only

26. pAAV_hSyn-PdCO-mScarlet-WPRE (AAV1)

    Viral Prep

    #198510-AAV1

    Purpose

    Ready-to-use AAV1 particles produced from pAAV_hSyn-PdCO-mScarlet-WPRE (#198510). In addition to the viral particles, you will also receive purified pAAV_hSyn-PdCO-mScarlet-WPRE plasmid DNA. Syn-driven expression of optimized PdCO in frame with mScarlet. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Ofer Yizhar

    Article

    Wietek et al Nat Methods. 2024 May 29. doi: 10.1038/s

    Promoter

    Syn

    Tags

    mScarlet

    Available Since

    Jan. 27, 2025

    Availability

    Academic Institutions and Nonprofits only

27. pGP-AAV-syn-FLEX-jGCaMP7f-WPRE (AAV Retrograde)

    Viral Prep

    #104492-AAVrg

    Purpose

    Ready-to-use AAV Retrograde particles produced from pGP-AAV-syn-FLEX-jGCaMP7f-WPRE (#104492). In addition to the viral particles, you will also receive purified pGP-AAV-syn-FLEX-jGCaMP7f-WPRE plasmid DNA. Syn-driven, Cre-dependent GCaMP7f calcium sensor. These AAV preparations are suitable purity for injection into animals. These AAV were produced with a retrograde serotype, which permits retrograde access to projection neurons.

    Depositor

    Douglas Kim, GENIE Project

    Article

    Dana et al Nat Methods. 2019 Jul;16(7):649-657. doi

    Promoter

    Syn

    Available Since

    June 14, 2018

    Availability

    Academic Institutions and Nonprofits only

28. pGP-AAV-syn-FLEX-jGCaMP7s-WPRE (AAV Retrograde)

    Viral Prep

    #104491-AAVrg

    Purpose

    Ready-to-use AAV Retrograde particles produced from pGP-AAV-syn-FLEX-jGCaMP7s-WPRE (#104491). In addition to the viral particles, you will also receive purified pGP-AAV-syn-FLEX-jGCaMP7s-WPRE plasmid DNA. Synapsin-driven, Cre-dependent, GCaMP7s calcium sensor. These AAV were produced with a retrograde serotype, which permits retrograde access to projection neurons. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Douglas Kim, GENIE Project

    Article

    Dana et al Nat Methods. 2019 Jul;16(7):649-657. doi

    Promoter

    Syn

    Available Since

    June 14, 2018

    Availability

    Academic Institutions and Nonprofits only

29. pAAV.hSyn-FLEX.iGABASnFR.F102G (AAV1)

    Viral Prep

    #112164-AAV1

    Purpose

    Ready-to-use AAV1 particles produced from pAAV.hSyn-FLEX.iGABASnFR.F102G (#112164). In addition to the viral particles, you will also receive purified pAAV.hSyn-FLEX.iGABASnFR.F102G plasmid DNA. Synapsin-driven, Cre-dependent iGABASnFR.F102G GABA sensor. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Loren Looger

    Article

    Marvin et al Nat Methods. 2019 Aug;16(8):763-770. doi

    Promoter

    Syn

    Available Since

    Jan. 3, 2019

    Availability

    Academic Institutions and Nonprofits only

30. AAV-FLEX-Arch-GFP (AAV1)

    Viral Prep

    #22222-AAV1

    Purpose

    Ready-to-use AAV1 particles produced from AAV-FLEX-Arch-GFP (#22222). In addition to the viral particles, you will also receive purified AAV-FLEX-Arch-GFP plasmid DNA. CAG-driven cre-dependent Arch-GFP expression for optogenetic neural inhibition. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Edward Boyden

    Article

    Chow et al Nature. 2010 Jan 7. 463(7277):98-102.

    Promoter

    CAG

    Tags

    GFP (Cre-dependent)

    Available Since

    Feb. 21, 2018

    Availability

    Academic Institutions and Nonprofits only