1,001 results

1. pAAV-CaMKIIa-hChR2(E123A)-mCherry (AAV9)

   Viral Prep

   #35506-AAV9

   Purpose

   Ready-to-use AAV9 particles produced from pAAV-CaMKIIa-hChR2(E123A)-mCherry (#35506). In addition to the viral particles, you will also receive purified pAAV-CaMKIIa-hChR2(E123A)-mCherry plasmid DNA. CaMKIIa-driven, humanized channelrhodopsin E123A mutant fused to mCherry for optogenetic activation. These AAV preparations are suitable purity for injection into animals.

   Depositor

   Karl Deisseroth

   Article

   Mattis et al Nat Methods. 2011 Dec 18;9(2):159-72. do

   Promoter

   CaMKII

   Tags

   mCherry

   Available since

   March 30, 2018

   Availability

   Academic Institutions and Nonprofits only

2. pAAV-S5E2-Gq-P2A-dTomato (AAV1)

   Viral Prep

   #135635-AAV1

   Purpose

   Ready-to-use AAV1 particles produced from pAAV-S5E2-Gq-P2A-dTomato (#135635). In addition to the viral particles, you will also receive purified pAAV-S5E2-Gq-P2A-dTomato plasmid DNA. Expression of Gq-DREADD and dTomato (physically separate) under the control of the E2 regulatory element. These AAV preparations are suitable purity for injection into animals.

   Depositor

   Jordane Dimidschstein

   Article

   Vormstein-Schneider et al Nat Neurosci. 2020 Dec;23(12):1629-1636.

   Promoter

   Tags

   dTomato (physically separate, not a fusion protein)

   Available since

   Nov. 29, 2021

   Availability

   Academic Institutions and Nonprofits only

3. pOTTC1032 - pAAV EF1a Nuc-flox(mCherry)-EGFP (AAV8)

   Viral Prep

   #112677-AAV8

   Purpose

   Ready-to-use AAV8 particles produced from pOTTC1032 - pAAV EF1a Nuc-flox(mCherry)-EGFP (#112677). In addition to the viral particles, you will also receive purified pOTTC1032 - pAAV EF1a Nuc-flox(mCherry)-EGFP plasmid DNA. EF1a-driven, Cre-dependent color switch. This AAV directs expression of nuclear mCherry in the absence of Cre. In the presence of Cre, nuclear EGFP (and not mCherry) will be expressed. These AAV preparations are suitable purity for injection into animals.

   Depositor

   Brandon Harvey

   Article

   Back et al Neuron. 2019 Feb 8. pii: S0896-6273(19)3

   Promoter

   EF1a

   Tags

   mCherry (Cre-negative cells), EGFP (Cre-positive cells)

   Available since

   Sept. 8, 2020

   Availability

   Academic Institutions and Nonprofits only

4. pGP-AAV-syn-FLEX-jGCaMP7c variant 1513-WPRE (AAV1)

   Viral Prep

   #105322-AAV1

   Purpose

   Ready-to-use AAV1 particles produced from pGP-AAV-syn-FLEX-jGCaMP7c variant 1513-WPRE (#105322). In addition to the viral particles, you will also receive purified pGP-AAV-syn-FLEX-jGCaMP7c variant 1513-WPRE plasmid DNA. Synapsin-driven, Cre-dependent jGCaMP7c expression. jGCaMP7c exhibits high contrast between peak fluorescence and resting fluorescence. It is useful for activity imaging of large populations of densely-labeled neurons because background fluorescence from inactive neurons is reduced. These AAV preparations are suitable purity for injection into animals.

   Depositor

   GENIE Project, Douglas Kim

   Article

   Dana et al Nat Methods. 2019 Jul;16(7):649-657. doi

   Promoter

   Syn

   Tags

   None

   Available since

   June 13, 2019

   Availability

   Academic Institutions and Nonprofits only

5. pAAV.hSynap-FLEX.SF-Venus-iGluSnFR.A184S (AAV1)

   Viral Prep

   #106183-AAV1

   Purpose

   Ready-to-use AAV1 particles produced from pAAV.hSynap-FLEX.SF-Venus-iGluSnFR.A184S (#106183). In addition to the viral particles, you will also receive purified pAAV.hSynap-FLEX.SF-Venus-iGluSnFR.A184S plasmid DNA. Synapsin-driven, Cre-dependent SF-Venus-iGluSnFR.A184S glutamate sensor. These AAV preparations are suitable purity for injection into animals.

   Depositor

   Loren Looger

   Article

   Marvin et al Nat Methods. 2018 Nov;15(11):936-939. do

   Promoter

   Syn

   Tags

   Venus (Cre-dependent)

   Available since

   Dec. 26, 2018

   Availability

   Academic Institutions and Nonprofits only

6. pAAV.GFAP.SF-iGluSnFR.A184S (AAV1)

   Viral Prep

   #106192-AAV1

   Purpose

   Ready-to-use AAV1 particles produced from pAAV.GFAP.SF-iGluSnFR.A184S (#106192). In addition to the viral particles, you will also receive purified pAAV.GFAP.SF-iGluSnFR.A184S plasmid DNA. GFAP-driven expression of SF-iGluSnFR.A184S. These AAV preparations are suitable purity for injection into animals.

   Depositor

   Loren Looger

   Article

   Marvin et al Nat Methods. 2018 Nov;15(11):936-939. do

   Promoter

   GFAP

   Tags

   None

   Available since

   Sept. 11, 2020

   Availability

   Academic Institutions and Nonprofits only

7. pAAV.hSynap.ChETA(E123T/H134R)-eYFP.WPRE.hGH (AAV9)

   Viral Prep

   #100049-AAV9

   Purpose

   Ready-to-use AAV9 particles produced from pAAV.hSynap.ChETA(E123T/H134R)-eYFP.WPRE.hGH (#100049). In addition to the viral particles, you will also receive purified pAAV.hSynap.ChETA(E123T/H134R)-eYFP.WPRE.hGH plasmid DNA. Synapsin-driven ChETA(E123T/H134R)-EYFP expression for optogenetic neural activation. These AAV preparations are suitable purity for injection into animals.

   Depositor

   Karl Deisseroth

   Promoter

   Syn

   Tags

   EYFP

   Available since

   Feb. 21, 2018

   Availability

   Academic Institutions and Nonprofits only

8. pAAV.CAG.iAChSnFR (AAV1)

   Viral Prep

   #137955-AAV1

   Purpose

   Ready-to-use AAV1 particles produced from pAAV.CAG.iAChSnFR (#137955). In addition to the viral particles, you will also receive purified pAAV.CAG.iAChSnFR plasmid DNA. CAG-driven iAChSnFR acetylcholine sensor. These AAV preparations are suitable purity for injection into animals.

   Depositor

   Loren Looger

   Article

   Borden et al bioRxiv 2020

   Promoter

   CAG

   Tags

   None

   Available since

   Oct. 28, 2021

   Availability

   Academic Institutions and Nonprofits only

9. pAAV-nEF-Con/Foff 2.0-ChR2-mCherry (AAV8)

   Viral Prep

   #137143-AAV8

   Purpose

   Ready-to-use AAV8 particles produced from pAAV-nEF-Con/Foff 2.0-ChR2-mCherry (#137143). In addition to the viral particles, you will also receive purified pAAV-nEF-Con/Foff 2.0-ChR2-mCherry plasmid DNA. nEF-driven, Cre-dependent expression of ChR2-mCherry for optogenetic activation (inhibited in the presence of Flp recombinase). These AAV preparations are suitable purity for injection into animals.

   Depositor

   Karl Deisseroth, INTRSECT 2.0 Project

   Article

   Fenno et al Neuron. 2020 Jun 20. pii: S0896-6273(20)

   Promoter

   nEF

   Tags

   mCherry (Cre-dependent)

   Available since

   Feb. 25, 2021

   Availability

   Academic Institutions and Nonprofits only

10. pAAV-synapsin-HaloCaMP1a-EGFP (AAV1)

    Viral Prep

    #138327-AAV1

    Purpose

    Ready-to-use AAV1 particles produced from pAAV-synapsin-HaloCaMP1a-EGFP (#138327). In addition to the viral particles, you will also receive purified pAAV-synapsin-HaloCaMP1a-EGFP plasmid DNA. Synapsin-driven HaloCaMP1a, a far-red calcium sensor, fused to EGFP. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Eric Schreiter

    Article

    Deo et al Nat Chem Biol. 2021 Jun;17(6):718-723. d

    Promoter

    Syn

    Tags

    EGFP

    Available since

    Sept. 15, 2021

    Availability

    Academic Institutions and Nonprofits only