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We narrowed to 434 results for: pme

Showing: 181 - 200 of 434 results
  1. Plasmids 101: The Promoter Region – Let's Go!

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    Blog Post
    ...only in certain tissues or at certain times in development or there may be ways to turn them on or off at...tables above do not delve into the tissue or development-specific promoters available to scientists. Plasmids...
  2. Harnessing Bacterial Toxins for Allelic Exchange

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    Blog Post
    ...experiment? Find the pTOX plasmids here! Continued development of new allelic exchange vectors Allelic exchange...clear advantages, and are hopeful that continued development of allelic exchange vectors will produce an array...
  3. Antibodies 101: Single Chain Fragment Variables (scFvs)

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    Blog Post
    ...Principles and Clinical Application. Clinical and Developmental Immunology 2012:1–15 . https://doi.org/10.1155...reagent sharing platform for antibodies, the Developmental Studies Hybridoma Bank Learn more about the ...
  4. Finding Your Perfect Job After University

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    Blog Post
    ...practicalities of working in the field with the most basic equipment and was a tremendously positive experience. I ...to Choose a Good Mentor for Your Professional Development ...
  5. Quick Guide to All Things Lentivirus

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    Blog Post
    ...sensors. Retroviral vector background Until the development of viral vectors, gene transfer into mammalian...was a disadvantage particularly for clinical development. In addition, MoMLV is inefficient at infecting...
  6. Finding Your Science Policy Path

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    Blog Post
    ...organizations and science blogs. Other avenues for skill development include leadership of extracurricular organizations...career options Read blog posts on professional development ...
  7. Antibodies 101: Antibody Engineering and Directed Evolution

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    Blog Post
    ... a large scale — some is done on much smaller equipment on a lab bench. The best part? Less complicated...possibilities for synthetic antibody products and development methods. Despite recent advances, there is still...
  8. A Primer on Optogenetics: Introduction and Opsin Delivery

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    Blog Post
    ... one of the key scientists who pioneered the development of optogenetics, has genetically manipulated ...nrn3171. PMID: 22430017. 2. Fenno L, et al. The development and application of optogenetics. Annual review...
  9. Chemogenetics Guide

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    Guide
    ...attractive targets for development into chemogenetic tools. Studies of GPCRs led to development of mutated receptors...
  10. Gamma-Retroviral Vector Guide

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    Guide
    ...lead to activation of the oncogene and possible development of cancer. Pseudotyping Tropism dictates which...manufacturing. Molecular Therapy — Methods & Clinical Development , 28 , 116–128. https://doi.org/10.1016/j.omtm...
  11. Optogenetics Guide

    Type
    Guide
    ... novel ChRs from other algal species and the development of synthetic variants to enhance the functionality...channelrhodopsin variants: features, limitations and future developments. Exp Physiol, 96 (1), 19–25. https://doi.org...
  12. Delivery Methods for Generating iPSCs

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    Blog Post
    ...iPSCs and measuring their ability to direct the development of a mouse. Since many of these functional tests...history, mechanisms, and applications." Genes & Development 24, no. 20 (2010): 2239-263. PubMed PMID: 20952534...
  13. Adenovirus Guide

    Type
    Guide
    ...verified, and linearized with the restriction enzyme PmeI . This construct is then transformed into AdEasier...cassette in one single viral particle. Vaccine Development rAdV vectors are highly immunogenic because they...
  14. 28 Hot Plasmid Technologies from 2015

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    Blog Post
    ...pairs in series with unique spacer sequences (pMemoryArray) gives a DNA sequence capable of recording 11...reporter constructs or as the fully assembled pMemoryArray.   Yang et al., Nat Methods 2014 Dec;11(12...transactivators available through Addgene. The development of dCas9 and dCas9-fusion proteins has dramatically...
  15. Adeno-associated virus (AAV) Guide

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    Guide
    ...be limited to small transgenes, enabling the development of further AAV applications. Read our blog post...opens in a new window) Merten, O. W. (2024). Development of stable packaging and producer cell lines for...
  16. Using AAV for Neuronal Tracing

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    Blog Post
    ...like these may be a starting point for future developments in the field of AAV vectors. Conclusion An ideal...intracellular transport of AAV could facilitate the development of more powerful AAV serotypes, and perhaps lead...
  17. Viral Vectors 101: Systemic Capsids

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    Blog Post
    ...capsid. Molecular Therapy - Methods & Clinical Development, 26, 331–342. https://doi.org/10.1016/j.omtm.2022.07.010...Expression. Molecular Therapy - Methods & Clinical Development, 15, 320–332. https://doi.org/10.1016/j.omtm.2019.10.007...
Showing: 181 - 200 of 434 results