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Enter a sequence to perform a BLAST-based search of Addgene plasmid sequence databases.

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We narrowed to 497 results for: RAP

Showing: 201 - 220 of 497 results

  2. Chemogenetics vs. Optogenetics: Which Method Should I Choose?

    Type
    Blog Post
    ...sustained activation period is beneficial for use in therapeutic or behavioral applications where drawn out effects... by Designer Drugs): Chemogenetic Tools with Therapeutic Utility. Annual Review of Pharmacology and Toxicology...

  3. Antibodies 101: Affinity Tags

    Type
    Blog Post
    ...applications. Also, purifying GST by affinity chromatography requires proper folding of the tag, which prevents...to be purified by single step metal affinity chromatography. Purification of His fusion proteins from E...

  4. Antibodies 101: Fc Effector Functions

    Type
    Blog Post
    ... induce?  Fc receptors are intriguing from a therapeutic standpoint. Engineered monoclonal antibodies ...phagocytosis for effective macrophage-based cancer immunotherapy.Sci. Adv.8,eabl9171(2022).DOI:10.1126/sciadv.abl9171...

  5. CRISPR 101: Drug discovery and CRISPR

    Type
    Blog Post
    ...determine if a patient would respond to an existing therapy. In theory, CRISPR could even be used to generate...Cornerstones of CRISPR-Cas in drug development and therapy. Nat Rev Drug Discov (2017) 16(2):89-100. DOI: ...

  6. Fostering communication in remote collaborations

    Type
    Blog Post
    ...various tools, this may happen over email or using rapid communication tools such as Slack. Share data and...exchange project at the International Cancer Immunotherapy Conference in Frankfurt, Germany When funding...

  7. Running for Rare Disease, Running for FOP, Running for AJ

    Type
    Blog Post
    ...including Activin A. A commercially developed therapeutic antibody that binds Activin A and interferes ...experience is in both vaccine subunit design and therapeutic biologic design (ADCs) along with pre-clinical...

  9. Addgene Depositors Get More Citations

    Type
    Blog Post
    ...highly cited, we went to one of the largest bibliographic databases available, Web of Science. For each... publication, Web of Science provides basic bibliographic information and uses its vast network of articles...

  12. Scientists Map the SARS-CoV-2-Human Interaction Network

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    Blog Post
    ... that can be targeted (hopefully by existing therapeutics that are safe, effective, and already FDA-approved...druggable) is a key step in our strategy to throw a therapeutic monkeywrench into the virus’ hijacking of human...

  13. Cultivating Community Science at BosLab

    Type
    Blog Post
    ...proof-of-concept experiments for discovering novel therapeutics. Dave is a chemical biologist with a Ph.D. from... first yeast transformations! Dennis Oleksyuk, Raphael Laurenceau, and Tami Pudina have initiated a soil...

  14. Plasmids 101: NGS Quality Control for Pooled Libraries

    Type
    Blog Post
    ... mixture on solid media. The colonies are then scraped off the plates and pelleted for DNA extraction....amplification looks like, but by looking at these kinds of graphs, making sure few/no plasmids have dropped out, ...

  15. Celebrate National Book Month with Addgene

    Type
    Blog Post
    ..., why it affects our emotions, and even what therapeutic properties it has. As with other works of Dr.... psychology major and a musician, I found myself rapt by this book! Far from a work of glib pop psychology...

  19. Synthetic Photobiology: Optogenetics for E. coli

    Type
    Blog Post
    ...figure below). Subsequent exposure to red light rapidly deactivates the system. Voigt’s lab used this system...GFP reporter. Subsequent exposure to red light rapidly deactivates the system. Version 1 of this far-red...

  20. A Deep Dive into BioBuilder

    Type
    Blog Post
    ...students to explore how engineering fields rely on rapid prototyping to develop and test hypotheses. Students...Students then use cellular extracts as a means to rapidly prototype DNA circuits and logic gates. This BioBuilder-Caltech...
Showing: 201 - 220 of 497 results