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We narrowed to 46 results for: RAP

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Showing: 1 - 20 of 46 results

  1. Ras Pathway

    Type
    Collection
    ...guanine nucleotide dissociation stimulator RAPGEF RAPGEF1 RAPGEF2 Rap guanine nucleotide exchange factor RAS...protein, LST8 homolog MTOR Mechanistic target of rapamycin NF1 Neurofibromin 1 NFE2L2 Nuclear factor, erythroid...their downstream targets. Rajalingam K, Schreck R, Rapp UR, Albert S. Biochim Biophys Acta. 2007 Aug;1773... . Targeting RAS signalling pathways in cancer therapy. Downward J. Nat Rev Cancer. 2003 Jan;3(1):11-22...

  2. Immunology Research Plasmids and Resources

    Type
    Collection
    ... PILSAP ERAP2 endoplasmic reticulum aminopeptidase 2 FLJ23633, FLJ23701, FLJ23807, L-RAP, LRAP FCER1G ...oncostatin M receptor) CD130, CDw130, GP130, GP130-RAPS, IL6R-beta IL7 interleukin 7 IL-7 IL7R interleukin...RCCP2, c-Met MIA melanoma inhibitory activity CD-RAP MIF macrophage migration inhibitory factor (glycosylation-inhibiting...FGR, YES MGC45350, SLK, SYN GRAP2 GRB2-related adaptor protein 2 GADS, GRAP-2, GRB2L, GRBLG, GRID, GRPL...cells that can recognize a recurrent infection and rapidly initiate a secondary immune response. Browse Plasmids...CATL, CTSL, FLJ31037, MEP CTSS cathepsin S MGC3886 ERAP1 endoplasmic reticulum aminopeptidase 1 A-LAP, ALAP...

  3. Neurodegeneration Research Collection

    Type
    Collection
    ...window) An organization with a mission to rapidly develop therapeutics that will slow the progression of Huntington...partly understood, and there are no effective therapies to prevent, treat, or cure most of these disorders...SOX10, OLIG2, and NKX6.2 transcription factors for rapid and efficient generation of oligodendrocytes from...portfolio of biomolecular tools and emphasizes their rapid and broad dissemination to the research community...agenda and to ensuring the development of improved therapies for those living with Parkinson's today. The Michael...available to the scientific community at low cost, with rapid delivery. Includes antibodies, viral vectors, animal...

  4. CRISPR Plasmids - Tagging

    Type
    Collection
    ...into human FBL locus Jorgensen Lab SapTrap CRISPR/Cas Toolkit SapTrap is a modular toolkit from Erik Jorgensen's...insert genetic tags in the C. elegans genome. The SapTrap reaction produces a single plasmid targeting vector...26 plasmids; 21 of the plasmids are for use in SapTrap reactions for targeting vector assembly, and the...prebuilt Unc-32::GFP targeting vector. Jorgensen Lab SapTrap CRISPR/Cas Toolkit Kanemaki Lab Auxin-Inducible...cytoplasmic proteins, which can then be depleted very rapidly after the addition of auxin to the culture medium...

  5. mTOR Pathway

    Type
    Collection
    ...mTORC2. Each complex contains a unique subunit: raptor for mTORC1, and rictor for mTORC2. Background mTORC1...threonine kinase 11 mTOR Mechanistic target of rapamycin NF1 Neurofibromin 1 PRAS40 Also known as AKT1S1...RRAGA RRAGB RRAGC RRAGD Ras-related GTP binding Raptor Also known as RPTOR; Regulatory associated protein...associated protein 1 mTOR Mechanistic target of rapamycin p53 TP53; tumor protein p53 PDK1 Pyruvate dehydrogenase...10.1016/j.cell.2012.03.017. PubMed PMID: 22500797 . Rapamycin: one drug, many effects. Li J, Kim SG, Blenis ...

  6. Worm Expression Resources

    Type
    Collection
    ...widely used as a genetic model organism due to their rapid life cycle (3 days from egg to adult) and easy lab...along with links to protocols, can be found below: SapTrap-SEC kit for C. elegans genome engineering - Bob...kit can be found at the Goldstein Lab website . SapTrap CRISPR/Cas Toolkit - Erik Jorgensen Lab. A collection...Efficiency Fluorescent Tagging of Endogenous Genes with SapTrap Even more elegant: Single injection CRISPR/Cas9...

  7. Brain Initiative Collection

    Type
    Collection
    ...portfolio of biomolecular tools and emphasizes their rapid and broad dissemination to the research community...for Cre-dependent expression of Venus-tagged parapinopsin driven by the CAG promoter. Used for photoswitchable...for Cre-dependent expression of Venus-tagged parapinopsin driven by the Ef1a promoter. Used for photoswitchable...version of DLX enhancer). AAV vector for strong & rapid SYFP2 expression in forebrain GABAergic interneurons...

  8. Rett Syndrome

    Type
    Collection
    ...MECP2 reactivation, RNA editing, gene replacement therapy, RNA trans-splicing, and protein replacement to...They are also an important tool for developing therapeutic strategies to treat Rett syndrome and restore...disease and for the development of successful therapeutics. ATCC - (Link opens in a new window) LUHMES ...CRISPR Tools CRISPR technology is a promising therapeutic approach for precise editing of mutations in ...

  9. Mammalian RNAi Tools

    Type
    Collection
    ...siRNAs): mechanism, therapeutic targets, and delivery strategies for cancer therapy . International Journal... genes with potentially harmful mutations in therapeutic settings. As a tool in mammalian cell systems...

  10. Antibody Plasmid Collection

    Type
    Collection
    ...single mammalian expression vector A tool kit for rapid cloning and expression of recombinant antibodies...2006 Dec 7;6:46. John McCafferty CRISPR system to rapidly engineer the constant immunoglobulin domains to...single domain antibodies for the conformational trapping of membrane proteins. Elife. 2018 May 24;7. ...

  11. Arf GTPase Family

    Type
    Collection
    ...Bacterial (pET) GAP Arap1 (CENTD2) 116985 1450 GAP Arap2 (CENTD1) 116984 1704 GAP Arap3 (CENTD3) 64411 1544...

  13. Zhang Lab CRISPR Page

    Type
    Collection
    ...SapI, which will reveal sticky ends to enable the rapid ligation of annealed and phosphorylated oligos designed...

  14. Plasmids for Stem Cell Research

    Type
    Collection
    ... an excellent unlimited stem cell source for therapeutic use. Since 2006, scientists have developed many...e16. Yang iPSCs Bipolar Neurons Lentiviral Human Rapid neurogenesis through transcriptional activation ...Weiss iPSCs & iPSC-NPCs Neurons Lentiviral Human Rapid Ngn2-induction of excitatory neurons from hiPSC-...

  15. Fluorescent Protein Guide: Biosensors

    Type
    Collection
    ...Monitoring the action of redox-directed cancer therapeutics using a human peroxiredoxin-2-based probe. Nat...Single fluorescent protein biosensor for maltose Rapid construction of metabolite biosensors using domain-insertion...Single fluorescent protein biosensor for trehalose Rapid construction of metabolite biosensors using domain-insertion...sensors A Genetically Encoded Fluorescent Sensor for Rapid and Specific In Vivo Detection of Norepinephrine...

  16. TALEN Guide

    Type
    Collection
    ...specific gene or your anxiously investigating gene therapy options for a rare disease in humans, TAL effectors... key tool in your plasmid toolbox. Addgene has rapidly become an important resource for this new technology...

  17. AAV Molecular Tools

    Type
    Collection
    ...transactivators and tools for affinity purification (TRAP)....affinity purification (which can be used for viral TRAP). ID Name Expression System Activity Serotype PI...

  18. Zebrafish Plasmid Collection

    Type
    Collection
    ...of genetics and developmental biology. With its rapid development (embryogenesis is complete in ~3 days...MAZERATI platform - Leonard Zon Lab. A platform to rapidly model potential cancer drivers in vivo. Biotagging...

  19. COVID-19 Resources

    Type
    Collection
    ...at Protocols.io (Link opens in a new window) For rapid detection of the 2019 novel coronavirus SARS-CoV... host cells . Signal transduction and targeted therapy, 5 (1), 283. https://doi.org/10.1038/s41392-020...

  20. Luciferase Plasmid Collection

    Type
    Collection
    ...Lentiviral Nadav Ahituv 212935 pGL4.84(hRlucCP/Puro) RapidResponse™ Renilla Vector for investigating regions controlling...FRB-Nluc : Split firefly luciferase reporter of rapamycin-inducible interaction. nLuc and cLuc : Constructs...
Showing: 1 - 20 of 46 results