We narrowed to 215 results for: pme i

... ADAR1, which converts adenosine to inosine (A-to-I) within double-stranded RNA. They hypothesized that...move discoveries from the lab bench into drug development. HiBiT technology helps close this gap! Bridging...

...T. Dargitz, R. Wright, A. Khanna, F. H. Gage, and I. M. Verma, “Functional Gene Correction for Cystic ...efficient manner than ever before, thanks to the development of site-specific nucleases (CRISPR/Cas9, TALENs...

...ever since there were plasmids to share. Back when I was in the lab, if you read a paper and saw an interesting...Hooper, PhD, has also worked with R&D for product development and now specializes in supporting Promega cellular...

...gang, Mesik, L., Liang, F., Tao, H. W., & Zhang, L. I. (2017). AAV-Mediated Anterograde Transsynaptic Tagging...vivo. Molecular Therapy - Methods & Clinical Development, 3, 16062. https://doi.org/10.1038/mtm.2016.62...

...that antibodies can be used for a lot of purposes! I hope you appreciate how many types of antibodies are...reagent sharing platform for antibodies, the Developmental Studies Hybridoma Bank Learn more about nanobodies...

...crRNAs that bind to the template strand. Therefore, I suggest that picking a crRNA complementary to the ...manipulation of mammalian neural stem cells. Development 144: 635-648. PubMed PMID: 28096221. PubMed Central...

...Friedman, N., Brown, T. M., Lipscombe, D., Moore, C. I., Hochgeschwender, U., & Shaner, N. C. (2024). Efficient..., J. M., Gautam, D., Scarselli, M., Ruiz de Azua, I., Li, J. H., Rosemond, E., Ma, X., Gonzalez, F. J....., Mimura, K., English, J. G., Liu, J., Inoue, K. I., Kumata, K., Seki, C., … Minamimoto, T. (2020). Deschloroclozapine..., L. M., Lambert, G. G., Lipscombe, D., Moore, C. I., Shaner, N. C., & Hochgeschwender, U. (2024). Engineering...attractive targets for development into chemogenetic tools. Studies of GPCRs led to development of mutated receptors...

...Gallay, P., Ory, D., Mulligan, R., Gage, F. H., Verma, I. M., & Trono, D. (1996). In vivo gene delivery and... H., Yu, E. Y., An, D. S., Sabatini, D. M., Chen, I. S., Hahn, W. C., Sharp, P. A., Weinberg, R. A., &....2192803 PMID: 12649500 Timms, R. T., Tchasovnikarova, I. A., & Lehner, P. J. (2018). Differential viral accessibility...understand integration sites have led to the development of multiple genome-wide analysis pipelines to...barcoding libraries . Mouse Modeling Since the development of safer lentiviral vectors, they have been seen...differences. Molecular Therapy — Methods & Clinical Development , 21 , 451–465. https://doi.org/10.1016/j.omtm...sites. Molecular Therapy — Methods & Clinical Development , 20 , 792–800. https://doi.org/10.1016/j.omtm...

...Ramakrishnan, C., Mattis, J., Prakash, R., Diester, I., Goshen, I., Thompson, K. R., & Deisseroth, K. (2010). ...Davidson, T. J., O'Shea, D. J., Sohal, V. S., Goshen, I., Finkelstein, J., Paz, J. T., Stehfest, K., Fudim... novel ChRs from other algal species and the development of synthetic variants to enhance the functionality... advantages or disadvantages depending on the equipment available or your experimental design. Red light...channelrhodopsin variants: features, limitations and future developments. Exp Physiol, 96 (1), 19–25. https://doi.org...

.../doi.org/10.1038/nchembio.1753 Richter F, Fonfara I, Bouazza B, Schumacher CH, Bratovič M, Charpentier...Dalvie NS, Panda A, Fleming HE, Bhatia SN (2016) Development of Light-Activated CRISPR Using Guide RNAs with...

...., Podrebarac, D. M., Greenough, W. T., & Weiler, I. J. (2008). The use of total protein stains as loading...that each type of transfer requires different equipment. Wet transfers can be done in an insert in your...

....2022.12.006 PMID: 36620071 Mirow, M., Schwarze, L. I., Fehse, B., & Riecken, K. (2021). Efficient pseudotyping...lead to activation of the oncogene and possible development of cancer. Pseudotyping Tropism dictates which...manufacturing. Molecular Therapy — Methods & Clinical Development , 28 , 116–128. https://doi.org/10.1016/j.omtm...

...hsp70 ALS, motor neuron disease Caren Norden 105971 pME mKate2-dynactin1-811 DCTN1 mKate2 ALS, motor neuron...CMV, P10 Huntington's Cheryl Arrowsmith 112205 pBS-I-Sce1-eno2:Tau-IRES-egfp MAPT GFP, eno2 eno2 Parkinson's...Spinocerebellar Ataxia Richard Youle 176464 pVPS13D-I-EGFP VPS13D GFP CMV Spinocerebellar Ataxia Richard...

...Watanabe, M., Nishikawaji, Y., Kawakami, H., & Kosai, K. I. (2021). Adenovirus biology, recombinant adenovirus...verified, and linearized with the restriction enzyme PmeI . This construct is then transformed into AdEasier...cassette in one single viral particle. Vaccine Development rAdV vectors are highly immunogenic because they...

...PMID: 12663794 (Link opens in a new window) Kwon, I., & Schaffer, D. V. (2008). Designer gene delivery...be limited to small transgenes, enabling the development of further AAV applications. Read our blog post...opens in a new window) Merten, O. W. (2024). Development of stable packaging and producer cell lines for...