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We narrowed to 569 results for: CIT

Showing: 241 - 260 of 569 results

  2. Future of Research Conference - Remarkable Opening Session

    Type
    Blog Post
    ... at Boston University last week.  This fantastic city-wide effort was led by two amazing postdocs, Kristin...Postdoc Dilemma” which pretty much said it all.  She cited the oft quoted statistic that only 15% of current...

  4. CRISPR Guide

    Type
    Guide
    ... every genomic target. Due to its comparative simplicity and adaptability, CRISPR rapidly became the most...targeting multiple genomic locations or enhancing specificity, efficiency, or flexibility of the Cas enzyme...Vectors Engineering the Cas9 Endonuclease CRISPR specificity is determined by both the gRNA sequence and the... design, engineered Cas9s can enhance CRISPR specificity. SpCas9 (from Streptococcus pyogenes ) is the...many modified versions engineered to increase specificity and nuclease activity available. Engineered Cas9s...cleavage of target DNA. Cas9n increases target specificity. Since two nickases targeting opposite DNA strands...fidelity of Cas9 Researchers have also enhanced specificity by engineering Cas9 into high fidelity Cas9s ...

  6. New CRISPR Web Resources and #12DaysofCRISPR Recap

    Type
    Blog Post
    ...effectors. The diversity of tools is especially exciting, including histone acetylation by p300, histone...Editing with CRISPR and Enhancing CRISPR Targeting Specificity with eSpCas9, SpCas9-HF1, & HypaCas9 Day 10: ...

  7. CASTing Off for New Shores in Human Genome Editing

    Type
    Blog Post
    ...one dual CRISPR-transposon system before another exciting new advance emerges! The programmability and targeting...power of CRISPR combined with the large sequence capacity of transposons open whole new worlds to explore...

  9. Year of the Camelid: Antibody Style

    Type
    Blog Post
    ...even smaller, single-domain antibody fragment was exciting, and it wasn’t long until the field was off and...In addition to therapeutics, there is a lot of excitement around using sdAbs in diagnostic applications...

  10. Addgene at the ASM Microbe 2016 Conference

    Type
    Blog Post
    ...to network with scientists in this diverse and exciting field and to find out how we can serve them better...conference, it looks like there are plenty more exciting plasmid tools on the horizon for microbiology ...

  11. Safe Port in a Storm...How Addgene is Weathering the Pandemic

    Type
    Blog Post
    ...workforce for when we need to be working at full capacity to serve the scientific community. First, we applied...to quality materials and data. Addgene has some exciting new projects planned, and we look forward to supporting...

  14. Intro to Our Summer SciComm Series!

    Type
    Blog Post
    ...emails, most science communication work does not explicitly exclude people outside of the original recipients...the same page, we’re ready to get into the more exciting parts - learning more about science communication...

  15. Viral Vectors 101: What is a Virus (and a Viral Vector)?

    Type
    Blog Post
    ...particles. As a bonus, this increases the carrying capacity of the viral vector, increasing both safety and..., just to increase the viral vector’s carrying capacity. In order to allow the viral vectors to reproduce...

  16. Using Addgene's New Viral Service for Your Research

    Type
    Blog Post
    ...recently had this to say about the service: "I'm excited that Addgene is now offering virion preparations... improve our resources for future users. We’re excited to be distributing new types of materials. At the...

  17. Addgene's Top 10 Blog Posts of 2015

    Type
    Blog Post
    ...2015 has been an exciting year for the Addgene blog. We’ve released over 80 posts on a diverse array ...vivo gene delivery, but have limited packaging capacity making them difficult to use with CRISPR as the...

  20. New and Upcoming Viral Vectors - September 2019

    Type
    Blog Post
    ...2019), “this localization should improve the specificity of influence measurements by reducing photostimulation...continue to grow this collection. Of note, we are excited to release a Flp-dependent Cre AAV in AAV9 and ...
Showing: 241 - 260 of 569 results