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Enter a sequence to perform a BLAST-based search of Addgene plasmid sequence databases.

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We narrowed to 535 results for: genome

Showing: 321 - 340 of 535 results

  2. Build Your CRISPR Vocabulary

    Type
    Blog Post
    .... Structural biology of CRISPR–Cas immunity and genome editing enzymes. Nature Reviews Microbiology, 20...

  4. What's New in CRISPR - March 2020

    Type
    Blog Post
    ...cytosine base editor, BE3, induces a low frequency of genome-wide off-target DNA editing. Using several rapid...

  8. Impact of Genomic Variation on Function (IGVF) Consortium Collection

    Type
    Collection
    ...systematically perturbs the genome to assess the impact of genomic variation on genome function and phenotype...Consortium investigators to examine how genomic variation affects genome function to influence phenotypes. ...new window) aims to understand how genomic variation affects genome function, which in turn impacts phenotype...and map how genome function shapes phenotype, and how these processes are affected by genomic variation....will produce a catalog of the impact of genomic variants on genome function and phenotypes. Plasmids The...Depositor Collections IGVF Consortium Impact of Genomic Variation on Function (IGVF) Consortium Collection...window) (Link opens in a new window) The Impact of Genomic Variation on Function (IGVF) Consortium (Link opens...

  18. Viral Vectors

    Type
    Collection
    ... of their viral genome, with some having an RNA genome while others have a DNA genome. In addition, some...modified viral genomes. Naturally occurring viruses harbor genetic material (termed the viral genome) that, in...cell, its genome directs the production of more viruses. However, in theory, a viral genome could direct...alternate (non-virus-producing) genomes, naturally occurring viral genomes have been adapted into a plasmid-based...Virus Expression Genome Packaging Capacity Virus Size (nm) Cells Infected Target Cell Genome Integration Immune...expression and are permanently integrated into the host genome. Adeno-associated Virus (AAV) Plasmids | Guide ...generally are not permanently integrated into the host genome. AAVs are limited by their small packaging capacity...

  19. Cancer and the Immune System: Deciphering the Relationship

    Type
    Blog Post
    ... all of the above therapeutics, techniques like genome engineering have played a huge role. For instance...candidate at Binghamton University. She works on genome engineering and cancer immunotherapy, and is interested...

  20. CRISPR History and Development for Genome Engineering

    Type
    Collection
    ...that cleaves the genomic DNA. Type II CRISPR was the first system harnessed for genome engineering, with...anti-CRISPRs as off-switches for CRISPR genomic editing. Genome Engineering Applications In 2012, Jinek...valuable genome engineering tool. CRISPR... CRISPR CRISPR History CRISPR History and Development for Genome Engineering...prokaryotic immune system is especially amenable to genome engineering, offering flexibility and easy multiplexing...more so) for research applications, eclipsing past genome engineering technologies like zinc finger nucleases...sequences were initially discovered in the E. coli genome in 1987, but their function as a safeguard against...
Showing: 321 - 340 of 535 results