... N ‐oxide (CNO). CNO is a metabolite of the antipsychotic clozapine and seems to be pharmacologically ...however, it has off-target effects. The atypical antipsychotic drug olanzapine has also been shown to be an...common property of either typical or atypical antipsychotic drugs: is M1 agonism a pre-requisite for mimicking...mimicking clozapine's actions? Psychopharmacology, 178 (4), 451–460. https://doi.org/10.1007/s00213-004...cAMP Production in Striatopallidal Neurons. Neuropsychopharmacol, 38 (5), 854–862. https://doi.org/10.1038...