We narrowed to 503 results for: RAP

...understanding how the body works, generating new therapeutics, and sometimes formulating new biological concepts...

... he is interested in using CRISPR to develop therapeutic applications that better human health.     References...

...used in gene therapy applications to more specifically direct delivery of gene therapies. Common Uses ...gamma-retroviral vectors. Gene Therapy Gamma-retroviral vectors are a popular choice in gene therapy applications. There...There are many approved gamma-retroviral gene therapies to treat disease like cancer or immunodeficiency...Delivery of chimeric antigen receptor T cell (CAR-T) therapy is a particularly popular application of gamma-...and provide stable integration of the intended therapeutic. While similar to lentiviral vectors, they offer...centrifugation for CAR T cell manufacturing. Molecular Therapy — Methods & Clinical Development , 28 , 116–128...

...with an Internal Marker for Silencing Allows for Rapid Identification of Loss of Function Phenotypes. Plant...

... like for iPSC reprogramming and gene and cell therapy, and have potential to overcome some of the limitations...

...scientific process can help us understand how new therapies can be developed and applied. The current pandemic...

...what would happen if these corporations would extrapolate genetic engineering to exploit human beings. ...

...to convince me to spend a Saturday in the tourist-trap nightmare that is Times Square. But I made the sacrifice...

....e., happen most of the time). Figure 1 shows a graph from the BD® Spectrum Viewer, outlining a few commonly...

...crucial in the world of biological research, medical therapy, and even drug development (Grimm & Lavis, 2022...

...and purification is a snap using thin layer chromatography (Fessenden, 2009). However, these reagents ...

..., et al. “A versatile modular vector system for rapid combinatorial mammalian genetics.” Journal of Clinical...

...check out our blogpost on lab automation here!) Rapid Isolation – If you’re in a hurry, several manufacturers...

...? Base transversion editing is still advancing rapidly. If it follows a similar path to base transition...

...PMC3656821. 10. Aasen, T., et al., Efficient and rapid generation of induced pluripotent stem cells from...

...modular plasmids and enhanced MoClo protocols for rapid one-pot, multipart assembly, combinatorial design...library of constructs expressing GFP at 18 levels for rapid characterization in new organisms. Mobius Assembly...Mammalian Expression Stephan Gruber Platform for rapid assembly of expression vectors for multi-subunit... Drosophila John Doench 180-plasmid toolkit for rapid creation of CRISPR vectors compatible with various...

..., for example, could indicate that you had air trapped between the membrane and gel during the transfer...

...entry vectors deposited with Addgene), it can be rapidly shuttled into any compatible Gateway destination...entry plasmids are also available, allowing for rapid cloning of PCR products into donor plasmids without... a ligation step, making it an easy, cheap, and rapid cloning method. LIC depends on the addition of only...

... 4 ). Additional varenicline analogs, termed ultrapotent PSEMs (or uPSEMs), have also been developed as..., Basu J, Michaelides M, Sternson SM (2019). Ultrapotent chemogenetics for research and potential clinical...potent and selective chemogenetic actuator enables rapid neuronal and behavioral modulations in mice and ...

...comparative simplicity and adaptability, CRISPR rapidly became the most popular genome engineering approach...regulate known phenotypes, including resistances to chemotherapy drugs and toxins, cell viability, and tumor ...natural and engineered CjCas9 orthologs. Molecular Therapy , 31 (4), 1177–1187. PMID: 36733251 Harrington,...