...Hantman, A. W., Looger, L. L., Schaffer, D. V., & Karpova, A. Y. (2016). A Designer AAV Variant Permits Efficient...

... M., Gotthard, G., Tünnermann, J., Tänzer, T., Karpenko, J., Mertes, N., Xue, L., Uhrig, U., Reinstein...

...Prize included Jennifer Doudna and Emmanuelle Charpentier for their pioneering CRISPR/Cas9 work (now recognized...

...Heisig is a Research Associate in the lab of Arlene Sharpe at Harvard Medical School. His projects include...

... focus). This means that the images will appear sharp without interference from blurry out-of-focus light...

...Fonfara I, Bouazza B, Schumacher CH, Bratovič M, Charpentier E, Möglich A (2013) Engineering of temperature...

...mbio.00019-20 Singh AK, Carette X, Potluri L-P, Sharp JD, Xu R, Prisic S, Husson RN (2016) Investigating...

... Anti-TARPGamma2/Stargazin [N245/1R] TARPGamma2/Stargazin Rat Mouse IgG2a 177522 Anti-TARPGamma2/4/8 [... Mad3 Human Mouse IgG2a 220426 TARPGamma2/4/8 [N245/36R-2b] TARPGamma2/4/8 Rat Mouse IgG2a 220427 Kir2.3...IgG2a 231843 TARPGamma2/4/8 (Rattus norvegicus) recombinant mouse monoclonal antibody TARPGamma2/4/8 Rat Chimera... [N245/36R] TARPGamma2/4/8 Rat Mouse IgG2a 177523 Anti-Cav1.2 Ca2+ channel [N263/31R] Cav1.2 Ca2+ channel...

...Hantman, A.W., Looger, L.L., Schaffer, D.V., and Karpova, A.Y. (2016). A designer AAV variant permits efficient...

... viral service. Retrograde construct from Alla Karpova at Janelia Research Institute....preparations in a retrograde serotype from the Alla Karpova and David Schaffer laboratories. These viral vector... these viral preparations was performed by the Karpova lab. Results for our quality control experiments...

...Parkinson's Wade Harper 22594 Flag-HA-OTUD4 OTUD4 HA, FLAG CMV Gordon Holmes Syndrome Wade Harper 23026 pET9d-hnRNP-A1...pHAGE-eGFP-OPTN OPTN ALS Wade Harper 175760 pHAGE-FLAG-APEX2-OPTN OPTN Flag CMV ALS Wade Harper 175762 pHAGE-eGFP-...GFP CMV ALS Wade Harper 175763 pHAGE-eGFP-OPTN S473A 513A OPTN GFP CMV ALS Wade Harper 175764 pHAGE-eGFP-OPTN...OPTN GFP CMV ALS Wade Harper 175765 pHAGE-eGFP-OPTN E50K OPTN GFP CMV ALS Wade Harper 176267 pAAV-FLEX-P301L...177094 pHAGE-APPSw;T719N APP CMV Alzheimer's Wade Harper 177511 Anti-Frataxin [N191/7R] FXN CMV Friedreich...Cookson 193772 pENTR221-APP751 APP Alzheimer's Wade Harper 194004 VPS13D(deltaATG2-C/PH)^EGFP VPS13D GFP CMV...

... Chylinski K, Fonfara I, Hauer M, Doudna JA, Charpentier E. 2012. A programmable dual-RNA-guided DNA endonuclease...Shah SA, Saunders SJ, Barrangou R, Brouns SJ, Charpentier E, Haft DH, Horvath P, Moineau S, Mojica FJ, ...Zetsche B, Shalem O, Wu X, Makarova KS, Koonin EV, Sharp PA, Zhang F. 2015. In vivo genome editing using ...

...ARMET arginine-rich, mutated in early stage tumors ARP, MANF, MGC142148, MGC142150 ARMETL1 arginine-rich...ANG3, ANGPT3, ARP1, AngY, KIAA0351, UNQ162, dJ595C2.2 ANGPTL2 angiopoietin-like 2 ARP2, HARP, MGC8889 ANGPTL3...ANGPT5 ANGPTL4 angiopoietin-like 4 ANGPTL2, ARP4, FIAF, HFARP, NL2, PGAR, pp1158 ANGPTL5 angiopoietin-like...angiopoietin-like 5 - ANGPTL6 angiopoietin-like 6 AGF, ARP5 ANGPTL7 angiopoietin-like 7 AngX, CDT6, RP4-647M16.2, dJ647M16.1... nuclear receptor subfamily 2, group F, member 2 ARP1, COUP-TFII, COUPTFB, MGC117452, SVP40, TFCOUP2 NR2F6...HHM, MGC14611, PLP, PTHR, PTHRP PTN pleiotrophin HARP, HBGF8, HBNF, NEGF1 PYY peptide YY PYY1 QRFP pyroglutamylated...

...one reaction. However, some labs have observed a sharp decrease in success rate when assembling more than...

...K., Fonfara, I., Hauer, M., Doudna, J. A., & Charpentier, E. (2012). A programmable Dual-RNA–Guided DNA...Saunders, S. J., Barrangou, R., Brouns, S. J. J., Charpentier, E., Haft, D. H., Horvath, P., Moineau, S., Mojica...Shalem, O., Wu, X., Makarova, K. S., Koonin, E. V., Sharp, P. A., & Zhang, F. (2015). In vivo genome editing...Biotechnology . 38 (7), 824–844. PMID: 32572269 Charpentier, M., Khedher, A. H. Y., Menoret, S., Brion, A...

...Do so by gentle spreading. Some spreaders have a sharp edge that can scrape plates more abrasively at a...

...Zetsche B, Shalem O, Wu X, Makarova KS, Koonin EV, Sharp PA, Zhang F. Nature . 2015 Apr 9;520(7546):186-91...Langer 9, Anderson DG, Hacohen N, Regev A, Feng G, Sharp PA, Zhang F. Cell . 2014 Oct 9;159(2):440-55. doi...

...weak signals due to their monovalent nature. Darpins - Darpins are genetically engineered small proteins ...

...other types of affinity reagents such as scFvs, DARPins, Fabs, and secondary antibodies. To learn more ...

...produced with the AAV retro helper plasmid from the Karpova and Schaffer labs. See the Retrograde AAV Inventory...