... or activity can be achieved using switches, including riboswitches and optogenetic and chemogenetic tools...tissue or cell type specificity. An on/off genetic switch can be used for expression control. (c) Viral delivery...Dual expression Promoters, miRNAs, enhancers, and switches all take up precious cargo space in AAV vectors...

...Other ways to make the office more eco-friendly The switch to 100% renewable electricity is certainly not ...sustainability effort we’ve implemented at Addgene. The kitchen and office areas provide multiple streams for composting...

...advance your career, promote career growth, and/or switch your field of work, both in academia and in industry...specialized so it might lend itself more readily to a switch. 4. Do you want more autonomy?  Before my master...

...depolarization. They therefore function as a neuron “on switch.” Neuronal inhibition: Hyperpolarization Conversely...the cell. It therefore functions as a neuron “off switch.” Because of the differing peak absorption wavelengths...

...zebrafish embryo over an 80 minute time course.  By stitching together a stable scaffold and HA-binding regions...protein dynamics in vivo. In the future, this stitching technique could be applied to other epitopes and...

...activates transcription with the flick of a light switch and shuts off just as quickly. The original AraC...bacteriograph was created using 160 individual images stitched together. Image from Romano et al., 2021 with ...

...articles. Think we missed something smokin'? You can pitch a Hot Plasmids section (antibodies and viral preps...Andrews NP,  et. al. A toolbox of IgG subclass-switched recombinant monoclonal antibodies for enhanced...

...threshold like a switch that turns on or off. CRISPR shows a more continuous response - not switch-like at all...

...everything is conceptual, and the team that packages its pitch the best, wins. He explained that entrepreneurs ...the team works well, the idea is solid, and “the pitch is packaged to perfection”, seed money will hopefully...

...we’ll discuss inducible promoters, which can be switched from an OFF to an ON state, and how you might ...The Promoter Region Plasmids 101: Cre-lox Light-Switchable Two-Component Systems for E. coli Browse other...

...Independent control of immunoglobulin switch recombination at individual switch regions evidenced through Cre–...

...At the heart of their method is the RNA toehold switch, a RNA hairpin that can be designed to bind and...interest is a benefit of this method. Find the toehold switch microbiota/biomarker sensors here Studying the ...

...lab at the university that I went to. Making that switch from being a grad student to an employee, and being...life changed––she had a daughter. Needing a career switch because of the demanding hours in the lab, she ...

...FRET sensors, can reduce these unwanted variables. Twitch is a FRET-based calcium reporter derived from troponin...sensor for neuroscientists is CaMPARI. This sensor switches from green fluorescence to a red fluorescent state...

...including many things people already use. It makes the switch to Golden Gate Cloning easier because individual...with Golden Gate MoClo. The barrier for those switching to Golden Gate is a conceptual barrier. Sometimes...

...Photoactivatable / Photoconvertible: These proteins can switch their color when activated by a specific excitation...the mEOS proteins. Some proteins are reversibly switchable (e.g. rsEGFP, Dreiklang). Fluorescent Timers ...

...transcriptors,” transistor-like digital genetic switches that enable cellular computing. These logic gates...fluorescence. There are a few examples of engineered RNA switches, but we've not yet seen the development of enough...

..., compromising the photon budget. Likewise, the switch from ensemble imaging to single-molecule imaging...best method for live cell labeling and the easiest switch from fluorescent proteins given the relative simplicity...

...cultured rat hippocampal neurons. HaloTag dyes are switched from yellow to red at 0 h and back to red at 12...N.P., et al. (2019). A toolbox of IgG subclass-switched recombinant monoclonal antibodies for enhanced...

...important ease of use is for them (if they are to switch from paper to digital for example): “… 99% of respondents...retrievable, searchable and traceable. However, switching from paper to an electronic lab notebook requires...