We narrowed to 253 results for: Mac

1. An Interview with Connie Cepko - Gene Therapy, Plasmid Tools and Insights to Success

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   ...Gene Therapies 10:17-14:34 : Progress in Treating Macular Degeneration and Other Retinopathies 14:39-25:59...

2. Tips for Working in Industry & Success in Management: Interview with Crystal Shih

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   ...Investigator III at Novartis, a multinational pharmaceutical company based in Switzerland. After completing...

3. Podcast: Interview with Addgene's Founders

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   ... University and his Master of Arts in Law and Diplomacy, with a focus on international technology management...

4. Editor's Choice, July 2016

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   ... Expression in Mammals Recombinase-based State Machines Enable Order-dependent Logic in vivo As always...

5. Synthetic Biology, Artificial Chromosomes, iGEM & More - Interview with Tom Ellis

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   ...Oxford University and then obtained a PhD in Pharmacology from the University of Cambridge before spending...

6. Measuring Kinase Activity at the Single-Cell Level with Kinase Translocation Reporters (KTRs)

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   ...from Addgene! References Kudo, T., Jeknić, S., Macklin, D.N., Akhter, S., Hughey, J.J., Regot, S., & Covert...

7. What's New in CRISPR - December 2019

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   ...toolkit for epitope tagging in neurons Harold MacGillavry’s lab developed a CRISPR-based toolkit for targeted...

8. Editor's Choice, September 2016

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   ..., Lianna Swanson, and researcher at Sanofi Pharmaceuticals. This post highlights a rare disease, Fibrodysplasia...

9. Inside Addgene's 10 Year Anniversary Gala

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   ...The Addgene lab often works as a very well-oiled machine and this post was no exception - the rest of the...

10. Three Tips to Organize Your Lab Notebooks in the New Year

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    ... notebooks (ELNs) have gained traction with pharmaceutical companies, academic labs have been slower to...

11. CRISPR Guide

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    ...Smith, S. B., Meadows, S. K., Roberts, B. S., Mackiewicz, M., Mendenhall, E. M., & Myers, R. M. (2015)...

12. London Calling - Addgene’s New Europe Office in London

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    ...study the expression of an unknown protein in macrophages/monocytes using lentiviral expression vectors...

13. Addgene-Seeding Labs Plasmid Grant: Accelerating Science Globally - 5 Scientists, 4 Countries & 3 Continents!

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    ...Endophytes as sources of antibiotic” Biochemical Pharmacology 2017 Jun 15;134:1-17. PubMed PMID: 27984002....

14. Using Ultrasound to Image Bacteria in vivo: Acoustic Reporter Genes

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    ...substrate to produce bioluminescence. Substrate pharmacokinetics and biodistribution therefore introduce additional...

15. Sensing Neuronal Dopamine

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    ... vivo brain microdialysis: advances in neuropsychopharmacology and drug discovery." Expert opinion on ...

16. Five Questions to Ask If You're Deciding Between a Master's or PhD Program

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    ... you’re interested in (i.e. biotechnology, pharmaceuticals, etc.) Do their jobs sound interesting? Is ...

17. Understanding GPCR Signaling Using TRUPATH

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    ...well known and, as a result, a target of many pharmaceutical drugs, there is still only a partial understanding...

18. Chemogenetics vs. Optogenetics: Which Method Should I Choose?

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    ...Tools with Therapeutic Utility. Annual Review of Pharmacology and Toxicology 55:399–417 . https://doi.org/...

19. Plasmids 101: What is a plasmid?

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    ...replication within a plasmid by recruiting replication machinery proteins Antibiotic Resistance Gene Allows for...

20. Addgene @ Keystone: Thoughts on Precision Genome Engineering and Synbio

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    ...even compared his "memory" gene codes to a Turing machine (also discussed in the book). These synthetic biologists...

21. The Stingy Scientist: How the Baby Gel Box Was Born

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    ...illustration above) and bribed the guys in the hospital machine shop with coffee and donuts to cut the pieces of...

22. Plasmids 101: Antibiotic Resistance Genes

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    ...breaks Bactericidal 5-100 ug/mL Erythromycin macrolide Blocks 50S ribosomal subunit; inhibits aminoacyl...

23. What the HEK?

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    ...transfect the ‘helper’ plasmids (viral packaging machinery) along with the viral plasmid containing the cargo...

24. Hot Plasmids September 2018 - Optogenetics, RNA Localization, Fluorescent Protein, and Base-editing Tools

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    ...specific and much faster than any genetic or pharmacological manipulations on cells, and has potential use...

25. New and Upcoming Viral Vectors - Spring 2019

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    ...pAAV CD68-hM4D(Gi)-mCherry (CD68 is a  microglia/macrophage promoter) 121539  AAV5  pOTTC1596 - pAAV SYN1...

26. Three Tips for Preventing Viral Plasmid Recombination in Your Samples

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    ...References and resources References Al-Allaf FA, Tolmachov OE, Zambetti LP, Tchetchelnitski V, Mehmet H (...

27. 5 Uncommon Ways to Gain Career Skills During an Uncommon Time

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    ...meetings or that there’s some correct level of intimacy that creates the magic of a safe space. No matter...

28. Meet the New Addgene Board Members!

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    ...Therapeutics, which was acquired by Ultragenyx Pharmaceutical in 2017. As one of the original employees at...

29. Fluorescent Biosensors for Measuring Autophagic Flux

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    ... A., et al. "Rapid parallel measurements of macroautophagy and mitophagy in mammalian cells using a single...

30. Natural or synthetic? How Addgene’s dataset reveals trends in biological innovation

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    ... database. Through a series of simulations and machine learning, they created a classifier that predicts...

31. Rewiring Metabolic Circuitry with CRISPR RNA Scaffolds [Video]

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    ...Western Ontario studying plant-based recombinant pharmaceuticals. Follow him on Twitter @AdamChinFatt     References...

32. Quick Guide to Working with Drosophila Part 2: Controlling Gene Expression in Flies with Gal4/UAS

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    ... found in DNA. It then recruits transcription machinery to the site to induce gene expression. Thus, genes...

33. Creating accessible biology activities in schools with BioBits

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    ...complicated (and again, expensive) the different machines are, and how many regulations are in place to ...

34. Improving Transduction Efficiency with Exosome AAVs

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    ...secreted from producer cells also contain cellular macromolecules (e.g. proteins, nucleic acids) which possibly...

35. Virtual Science Conference Coming Up? Three Addgenies Share Their Experience

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    ...large conference room puts butterflies in your stomach, the virtual approach might be less stressful. ...

36. Hot Plasmids - December 2019 - CRISPR pooled library, LipoGlo, CRISPRa, and Voltage Imaging Tools

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    ...as well as the eFRET sensors, QuasAr-mOrange and MacQ-mCitrine. All of these sensors can detect action...

37. DAP arrays for multiplex gene editing

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    ...gRNAs are released by endogenous tRNA processing machineries, specifically, RNaseZ and RNaseP. Although the...

38. Using CRISPR/Cas9 to Edit Disease Out of the Genome

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    ...Application in Genetic Diseases: A Review.” Current pharmaceutical biotechnology. https://doi.org/10.2174/1389201021666200621161610...

39. Addgene-Seeding Labs plasmid grant round 3: microbial drug resistance and biofilms, antidiabetic plant components, visualizing brain injury - and a glowing robot fish

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    ...flow. Novel treatment options, as well as non-pharmacological solutions to modify the course of this condition...

40. Four Factors that Differentiate the Stem Cell Field

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    ...about his clinical trial patients with advanced macular degeneration; Laurenz Studer discussed his work...