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Enter a sequence to perform a BLAST-based search of Addgene plasmid sequence databases.

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We narrowed to 259 results for: OVA

Showing: 61 - 80 of 259 results

  1. New CRISPR Tools: Cas7-11 and PASTE

    Type
    Blog Post
    ...their initial assumption. Eugene Koonin and Kira Makarova, longtime collaborators of Omar and Jonathan and.... Using computational observations, Koonin and Makarova found that Cas7-11 appeared to have derived from...Özcan A, Krajeski R, Ioannidi E, Lee B, Gardner A, Makarova KS, Koonin EV, Abudayyeh OO, Gootenberg JS. Programmable...

  2. CRISPR Activation: A Practical Guide

    Type
    Blog Post
    ... scientific discovery through the creation of innovative technologies. To date his group has develop several...E, Lin S, Kiani S, Guzman CD, Wiegand DJ, Ter-Ovanesyan D, Braff JL, Davidsohn N, Housden BE, Perrimon...Tuttle M, Pruitt BW, Ewen-Campen B, Chari R, Ter-Ovanesyan D, Haque SJ, Cecchi RJ, Kowal EJK, Buchthal J,...

  3. Treating Muscular Dystrophy with CRISPR Gene Editing

    Type
    Blog Post
    ... in DMD patient myoblasts. They observed a 13% removal rate of exon 51, which resulted in appropriately...evaluated separately, increasing the time to clinical approval. Even with the challenges precision editing faces...Gootenberg JS, Kriz AJ, Zetsche B, Shalem O, Wu X, Makarova KS, Koonin EV, Sharp PA, Zhang F. In vivo genome...

  4. CRISPR 101: Epigenetics and Editing the Epigenome

    Type
    Blog Post
    ...Epigenetics began as a correlative field in which covalent modifications to DNA or histones, the proteins...downstream of Tet1 to restore the DNA after cytosine removal. Recently, Albert Cheng’s lab developed Casilio-ME...lab has deposited pX330a dCas9-LSD1 for targeted removal of H3K4me1/2 and H3K9me2 histone modifications....

  5. Viral Vectors 101: AAV Serotypes and Tissue Tropism

    Type
    Blog Post
    ...doi.org/10.1016/j.omtm.2022.07.010 Issa, S. S., Shaimardanova, A. A., Solovyeva, V. V., & Rizvanov, A. A. ...Lavzin, M., Ritola, K. D., Lindo, S., Michael, S., Kuleshova, E., Ojala, D., Huang, C.-C., Gerfen, C. R., Schiller...Hantman, A. W., Looger, L. L., Schaffer, D. V., & Karpova, A. Y. (2016). A Designer AAV Variant Permits Efficient...

  6. Tips for a 1st Time CRISPR User (by a 1st Time CRISPR User)

    Type
    Blog Post
    ..., Sullender M, Hegde M, Vaimberg EW, Donovan KF, Smith I, Tothova Z, Wilen C, Orchard R, Virgin HW, Listgarten...inactivation. Doench JG, Hartenian E, Graham DB, Tothova Z, Hegde M, Smith I, Sullender M, Ebert BL, Xavier...

  7. Illuminating Choices: A Guide to Selecting Fluorescent Dyes and Ligands

    Type
    Blog Post
    ...nucleic acids, or glycans. Fluorophores can also be covalently attached to self-labeling proteins. Some common...a genetically encoded enzyme variant tag that covalently reacts with a small substrate ligand motif attached... or the degree of labeling (DOL), and thorough removal of unconjugated dye molecules are critical for ...

  8. Cancer and the Immune System: Deciphering the Relationship

    Type
    Blog Post
    ...from Madame Curie), chemotherapy, and surgical removal of the tumor. However, these conventional therapies...the immune system from fighting cancer. Surgical removal causes increases in tumor cytokines like TGFβ and..."Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts...

  12. All Antibodies

    Type
    Collection
    ... neuroscience research. Institute for Protein Innovation Collection : Antibodies to highly conserved proteins...

  13. Why Do I Need an MTA Anyway?

    Type
    Blog Post
    ...we are here to make it fast and easy. Fast Approval: The UBMTA used by Addgene is internationally ...and familiarity with the UBMTA result in quick approvals, so your plasmid requests can get to your lab ...

  15. 2023 and 2024: Reflections and Looking Ahead

    Type
    Blog Post
    ...new partnership with the Institute for Protein Innovation (IPI), in which Addgene will distribute recombinant...the year, we’ll be celebrating with stories of innovation and impact made possible by the sharing of tools...

  16. Addgene is Expanding Our Viral Vector Service!

    Type
    Blog Post
    ...request will be reviewed by Addgene for legal approvals and technical compatibility with our production...not need to be placed immediately upon request approval. Once approved, the request will remain in your...

  18. Recombinases AAV Preps

    Type
    Collection
    ...produced with the AAV retro helper plasmid from the Karpova and Schaffer labs. See the Retrograde AAV Inventory...

  19. Bringing Sustainable Practices to the Lab: Recycling

    Type
    Blog Post
    ...environment. I recently attended the Go green! Innovative practices for laboratory waste symposium, sponsored... Bringing Sustainable Practices to the Lab: Innovations Bringing Sustainable Practices to the Lab: Easy...

  20. CASTing Off for New Shores in Human Genome Editing

    Type
    Blog Post
    ...individualized optimizations, safety testing, and approval. In contrast, a system that can deliver a healthy...doi.org/10.1038/s41586-019-1323-z Peters, J. E., Makarova, K. S., Shmakov, S., & Koonin, E. V. (2017). Recruitment...
Showing: 61 - 80 of 259 results