We narrowed to 254 results for: sms
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TypeBlog Post...protein structure that water-bound photosynthetic organisms use for buoyancy. These proteins allow dissolved...29300010. miRNA reporter vectors shed new light on mechanisms of miRNA-mediated gene regulation Article contributed...pathways. Despite several years of research, the mechanisms of miRNA regulation have yet to be fully elucidated...
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3 Challenges in Plant Synthetic Biology
TypeBlog Post...engineer a specific function in these multicellular organisms. However, the rewards are great if you take the...Additional work has also identified and characterized mechanisms and components of the circadian rhythm in petunias...understanding of the genetic pieces underpinning these mechanisms – our project wouldn’t be possible. A second ... -
BeHeard Award 2018: Diseases of Glycosylation, Arginine Mutagenesis, & Neural Development
TypeBlog Post...surprising. However, the molecular and cellular mechanisms behind the immune defects in CDG patients are...The primary focus of his lab’s research is the mechanisms by which proteins assemble into functional multi-subunit...development since 2000 and have shown several mechanisms by which they affect brain and muscle development... -
Illuminating Epigenetics with A FRET Based Biosensor
TypeBlog Post... have a specialized role within an organism. Mechanisms of epigenetic modifications The main mechanism.... Chromatin remodeling can occur by two main mechanisms, either through histone modifications, which ...development and progression of cancer through different mechanisms. New FRET based tools to study epigenetics Epigenetic... -
Magnetic Control of Proteins: More than a Dream
TypeBlog Post...and optogenetic tools exist, humans (like many organisms) are opaque, which makes most biomedical applications...There is a variety of research on whether and how organisms respond to magnetic fields (Karki et al., 2021...biomedical engineers, join efforts to explore the mechanisms and develop potential applications. Andrew is... -
Interview: Hodaka Fujii on enChIP, New CRISPR Tools, and More
TypeBlog Post...developing novel technologies to analyze molecular mechanisms of genome functions such as epigenetic regulation...epigenetic regulation. To elucidate molecular mechanisms of regulation of genome functions, we need to...will markedly accelerate research of regulation mechanisms of genome functions in the hope of developing... -
FLEx Technology and Optogenetics: Flipping the switch on gene expression with high spatial and temporal resolution
TypeBlog Post...vectors to study the neural circuitry behind the mechanisms of sleep and anesthesia. In Cre transgenic mice...optogenetics to understand the cellular and molecular mechanisms of the brain in vivo. Many thanks to our guest...rhodopsins: structures, functions, and molecular mechanisms." Chemical reviews 114.1 (2013): 126-163. PubMed... -
An “elegans” Approach to Better CRISPR/Cas9 Editing Efficiency
TypeBlog Post... a wide range of organisms and cell lines. In C. elegans, one of the model organisms which I use to study...methods – could greatly streamline editing in other organisms and systems, allowing rapid progress in a wide... -
Cancer and the Immune System: Deciphering the Relationship
TypeBlog Post...organs, and most importantly escape the immune mechanisms of the host. The cause, manifestation, diagnosis...this phase are able to outsmart the host immune mechanisms altogether and escape future immune surveillance...of colorectal cancer. Strategic immune evasion mechanisms - The tumor microenvironment Through interactions... -
Delivery Methods for Generating iPSCs
TypeBlog Post...plasmids due to lower activation of DNA-silencing mechanisms. While minicircles are typically smaller than...) studies focused on better understanding the mechanisms of reprogramming, and 2) studies with clinical...Hochedlinger. "Induced pluripotency: history, mechanisms, and applications." Genes & Development 24, no... -
Introducing Addgene's Microbiology Pages
TypeBlog Post...listed? Help us serve you! Let us know about other organisms we should include by emailing us at [email protected] narrow your keyword search to one of these organisms. Help us continue to develop resources for your... -
CRISPR-Cas14: a family of small DNA-targeting enzymes enabling high-fidelity SNP genotyping
TypeBlog Post...scientists to edit the genome of virtually any organisms on this planet, CRISPR-Cas systems were merely... to quickly detect the presence of infectious organisms (ex: SARS-CoV-2) and genetic mutations. By providing... -
Science as Art
TypeBlog Post...inner structures of delicate plants and other organisms without destroying the original, which could provide...Do you look for the beauty in the microscopic organisms on your lab bench? Let us know in the comments... -
Genetically-encoded Sparse Cell Labeling - A SPARC of Innovation
TypeBlog Post...versatile and can be applied across cell types and organisms by replacing the transcription factor binding ...the PhiC31 recombinase can work in other model organisms including mouse and fish, SPARC is likely generalizable... -
Some Like it Hot: Thermostable GeoCas9
TypeBlog Post... editing tool of choice for a number of model organisms: mammalian cells, yeast, drosophila, plants, worms...obligate thermophiles without the need to grow the organisms at lower than optimal temperatures. GeoCas9’s ... -
Reagent Repositories Are Speeding up Science During the Pandemic
TypeBlog Post...investigate the susceptibility of cells from different organisms to SARS-CoV-2 (Chu et al., 2020). An additional...for the advancement of scientific research, and mechanisms to maintain and grow these critical organizations... -
FlipGFP, a novel fluorescence protease reporter to study apoptosis
TypeBlog Post...cleavage. Secondly, fluorescence imaging of living organisms can be challenging due to issues with tissue autofluorescence...dynamics of apoptosis both in vitro and in living organisms to better study and understand these diseases ... -
R Bodies: Membrane-Rupturing Microscopic Tools
TypeBlog Post... can function to break membranes of different organisms. And finally, we demonstrated that R bodies can...speculatively, R bodies might endow divergent organisms with new functions. For inspiration, we can look... -
Viral Vectors 101: Inverted Terminal Repeats
TypeBlog Post... Vectors. Microorganisms, 12(2), 310. https://doi.org/10.3390/microorganisms1202031038399714. PMID: 38399714... -
Viral Vectors 101: Biosensors
TypeBlog Post...Viral delivery has several advantages over other mechanisms. For one, many viral platforms, such as AAV or...analyte. This can be difficult to achieve in whole organisms, but AAVs make it possible. In AAV systems, different...