...experiment! Thanks to Addgenies Brian O’Neill and Ina Ersing for contributing their expertise! References...administered systemically, without causing disease? Recombinant adeno-associated viral vectors, or rAAVs, can...Laminin receptor (LR)3 AAV receptor2   AAV9 Terminal N-linked galactose3 AAV receptor2 Laminin ...found to transduce skeletal muscle, cardiac, and retinal cells (Issa et al., 2023). AAV1 capsids are available...including liver, muscle, lung, CNS, kidney, and retinal cells (Issa et al., 2023; Wu, Asokan, et al., 2006...cardiac, pancreas, smooth muscle, CNS, kidney, and retinal cells (Issa et al., 2023; Wu, Asokan, et al., 2006...transduce liver, skeletal muscle, pancreatic, and retinal cells (Issa et al., 2023). AAV9 packaging plasmids...

...CMV ALS Trina Schroer 51221 CMV-CC2 DCTN1 CMV ALS Trina Schroer 51412 CMV-p150 DCTN1 CMV ALS Trina Schroer...17800 pM-ErbB4-delta-kinase ERBB4 GAL4-BD ALS Marius Sudol 17801 pM-ErbB4-delta-kinase-PY1 mutant ERBB4 GAL4... GAL4-BD ALS Marius Sudol 17802 pM-ErbB4-delta-kinase-PY3 mutant ERBB4 GAL4-BD ALS Marius Sudol 17803 ... CMV Parkinson's Mark Cookson 25071 2XMyc-LRRK2-Kinase LRRK2 Myc CMV Parkinson's Mark Cookson 25072 2XMyc-LRRK2...ERBB4 CMV ALS Yardena Samuels 29533 pcDNA3.1-ERBB4 (kinase dead) ERBB4 CMV ALS Yardena Samuels 29534 pcDNA3.1...ERBB4 CMV ALS Yardena Samuels 29544 pCDF1-ERBB4 (kinase dead) ERBB4 CMV ALS Yardena Samuels 29591 426Gal-FUS...type IE Arthur Riggs 37057 GFP-SMN SMN1 GFP CMV Spinal muscular atrophy Greg Matera 38005 pET-21a(+)/MBP-His-PINK1...

... Cancer Institute Finding the Causes of Small Intestinal Neuroendocrine Tumors Ramesh Shivdasani Dana-...Dana-Farber Cancer Institute Epigenetic Regulators of Intestinal Endocrine Cells and Carcinoid Tumors Qiao Zhou...Zhou Harvard University Epigenetic Regulators of Intestinal Endocrine Cells and Carcinoid Tumors Bradley ...Identifying Altered Epigenetic States and Drivers in Intestinal Carcinoid and Pancreatic Neuroendocrine Tumors...

... Kit Rinehart Recombinant Phosphoprotein Kit S. cerevisiae Advanced Gateway Destination Vectors TAL Effectors...synthetic regulatory elements, including promoters, terminators, repressors, activators, and more. Also contains...Mukhopadhyay Lab Efflux Pumps Voigt Lab Repressors , Terminators , Light Signaling , Sigma Factors , Resource ...

...18,885 human genes Puromycin Doench , Root Human inactivation pooled libraries 92385 Human CRISPR inhibition...Celltag library contains 19973 barcodes to combinatorially index cells for single-cell analysis of clonal... Celltag library contains 4934 barcodes to combinatorially index cells for single-cell analysis of clonal... Celltag library contains 5737 barcodes to combinatorially index cells for single-cell analysis of clonal...

...Mb-Fluoro-Phe B5 Pyl Fluoro-Phe B5 M. barkeri fluorinated phenylalanine derivatives Mammalian TAG Ryan ...Mb-Fluoro-Phe D6 Pyl Fluoro-Phe D6 M. barkeri fluorinated phenylalanine derivatives Mammalian TAG Ryan ...sites changes to UAG, RF1 function removed, ClpS inactivated, with Ubiquitin-UAG-sfGFP reporter George Church...codon, and tyrU gene replaced by tRNA variant inactivated by the truncation of the anticodon loop). Expresses...tyrTV and tyrU genes replaced by tRNA variant inactivated by the truncation of the anticodon loop). Expresses...

...sites by off-target quality. Validated for gene inactivation, NHEJ, and HDR. Includes a wide range of reference...and selection for Cas9-triggered homologous recombination Cas9-sgRNA target construct ; pMA122 (negative...pharyngeal co-injection marker); pDD104 (Cre recombinase) PDF, 105 KB Jaenisch CRISPR plasmid summary ... , pAC1 , pAC147 , pAC148 , pAC149 ; Gateway destination: pAC90 PDF, 1.1 MB Katic Nematode: Cas9 and gRNA...

...factors and the sensor behavior may differ from the original characterization (e.g. in vitro vs. in vivo , ...Zhou Calcium Twitch calcium indicator, based on C-terminal domain of troponin C Griesbeck Lab Twitch Plasmids...biosensors for mapping cellular concentrations of nicotinamide adenine dinucleotides. eLife. 2018 May 29;7....charges in live cells. Nat Biotechnol. 2017 Mar 13. Katharina Gaus Endo/Exocytosis Superecliptic pHluorin fused...-pHluorin Clathrin-mediated endocytosis is the dominant mechanism of vesicle retrieval at hippocampal ...expression of pH sensitive mt-mKeima) The ubiquitin kinase PINK1 recruits autophagy receptors to induce mitophagy...

...Find recombinant antibodies targeting epitope tags and common fusion proteins....common cellular proteins. These ready-to-use recombinant monoclonal antibodies undergo application-specific...and their use, visit our Antibody Guide . ID Recombinant Antibody Description Source Species Isotype Reactivity...

...Find recombinant antibodies targeting neuroscience-related proteins....in neuroscience research. These ready-to-use recombinant monoclonal antibodies undergo application-specific...and their use, visit our Antibody Guide . ID Recombinant Antibody Description Source Species Isotype Reactivity...

...Pooled Libraries Antibodies NeuroMab/Trimmer Lab Recombinant mAb Plasmid Collection Disease Research Michael... Simpson Reagents for improved expression of recombinant phosphoproteins - Rinehart FreeGenes Project ... Repressor Plasmids Sigma (σ) Factor Plasmids Terminator Plasmids Viral Vectors pLEG/pREG Modular Viral...

...Emission Brightness Find Plasmids mCardinal 604/659 18 All mCardinal plasmids from article mNeptune 600... in living animals. Further development of the original iRFP has resulted in a split fluorescence complementation...

...Browse Addgene's collection of recombinant monoclonal antibodies....Addgene distributes ready-to-use recombinant antibodies. These monoclonal antibodies undergo application-...Antibody Suggestion Form . Browse All Antibodies ID Recombinant Antibody Description Source Species Isotype Reactivity...

...you have the right to use the original plasmid. Distribution of the original plasmid is important because...which is a sample of the purified DNA from the original plasmid that was used to make the virus. In order...

...gamma GFP Tom Misteli 55068 mCherry-LaminA-C-18 Nuclear Envelope LaminA1 mCherry* Michael Davidson 98831 ...Davidson 98822 Lck-mTurquoise2 Plasma Membrane Lck N-terminal lipidation signal mTurquoise2 Dorus Gadella 98821...98821 Lck-mScarlet-I Plasma Membrane Lck N-terminal lipidation signal mScarlet-I Dorus Gadella 50057 pLYS1...

...in order to proceed with any adjustments to the original order. Turnaround Time Production of a Packaged...the approval of the MTA by your institution. Our final step of the QC process, viral genome sequence verification...in order to proceed with any adjustments to the original order. Experimental Disclaimer Due to the novel...

...Labeling from New England Biolabs Cancer Research from Sinai Health System Plasmids from the Structural Genomics... Antibodies Addgene distributes ready-to-use recombinant antibodies made from plasmids in our collection...as by our trusted partner labs. Learn More ID Recombinant Antibody Reactivity Recommended Applications ...

...as they receive their AAV prep from Addgene — eliminating the steps to produce, purify, and titer viral...research-grade use. Many chemogenetic, optogenetic, recombinase, and biosensor transfer plasmids in our repository...vivo testing. We recommend that you consult the original paper of your chosen AAV plasmid for more information...

...virus, plasmids expressing both the Cre and Flp recombinases to remove genes flanked by either loxP or frt...gene of interest from the PGK (phosphoglycerate kinase I) promoter pCDH-CMV4 72284 Express gene of interest...variety of reporters as well as the Cre and Flp recombinases. Genes can be cloned into these transfer vectors...

...Aqua Cyan Bacterial Expresses Aquamarine with N-terminal His tag pAquaN1 Cyan Mammalian Expresses mammalian...pCyPet-His Cyan Bacterial Expresses CyPet with C-terminal His tag SCFP3A Cyan Mammalian Express a gene of...pYPet-His Yellow Bacterial Expresses YPet with C-terminal His tag SYFP2 Yellow Mammalian Express a gene ...