We narrowed to 955 results for: ARC;
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TypeBlog Post...-level positions right out of college. Prior to March 2020, internships were a fiercely competitive endeavor...applying to several opportunities. In an age of scarcity, the rational human being will tend to clinch ...out other tools and resources for early career researchers Applying for jobs? Check out these blog posts...
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Viral Vectors 101: Gamma-Retroviral Packaging Systems
TypeBlog Post...γ-retroviruses (gamma-retroviruses) in cancer and stem cell research has prompted the development of multiple virus... 3’ LTR and are primarily used in gene therapy research to reduce promoter interference and/or drive high...Cycle Popular Retroviral Vectors and Their Use in Research More resources on addgene.org Addgene Protocols... -
Expanding the Targeting Scope and Editing Efficiency of Adenine Base Editors
TypeBlog Post...base editors for your research Read our CRISPR guide Find plasmids for your research ...compatible with all Cas9 and Cas12 homologs that the researchers tested, including SpCas9, SaCas9, LbCas12a, enAsCas12a... -
Screening for Successful Genome Editing with Digital PCR
TypeBlog Post...the University of Alberta. If you’re like many researchers these days, you are ready to take (if you haven...are often impractical for small projects. Most researchers instead turn to so-called “mismatch nuclease”...knockout of HIV co-receptor CCR5. Nucleic Acids Research 43, 5560–5571 (2015). PubMed PMID: 25964300. PubMed... -
Targeted Mutagenesis with EvolvR
TypeBlog Post...mutational abilities of PolI3m. This tag would allow researchers to trace the progeny of a single starting cell...flexibility to address many different types of research questions. Are you ready to start EvolvR-ing your...Perez-Pinera. "The continuously evolving CRISPR barcoding toolbox." Genome biology 19.1 (2018): 143. PubMed... -
REPLACR Mutagenesis: Replacing In Vitro Recombination Methods
TypeBlog Post...Site-directed mutagenesis (SDM) is one of the key tools researchers use to prove causation in molecular biology and...inactivating/activating mutations. In biomedical research, modeling patient mutations using SDM can help...Perfect Plasmid Backbone Find Plasmids for Your Research ... -
Advice for Starting a Biotech Company from a Grad Student turned Entrepreneur
TypeBlog Post...engineer and scientist, I like to envision that my research will have a direct impact on healthcare and the...result, I have occasionally pondered translating my research into a startup company. However, like many like-minded...incorporated into Novophage Therapeutics, Inc. in March 2009 and tested in the “market” by competing in ... -
What's New in CRISPR - November 2021
TypeBlog Post...recently identified Cas12f systems from uncultivated archaea are much smaller and would be ideal for such AAV...system (CasMINI) engineered from the uncultivated archaea Cas12f (Un1Cas12f1, or Cas14a1) system. The CasMINI...editing efficiency. The lab also optimized the architecture and amino acid sequence of the prime editor,... -
Tagging Optogenetics and Chemogenetics Receptors: Fluorescent Proteins and Other Options
TypeBlog Post... School of Medicine and a researcher at the Yerkes National Primate Research Center. Using a combination...combination of in vivo and anatomical techniques, her research aims to gain a deeper understanding of the physiology... -
RNA Extraction Without A Kit
TypeBlog Post...of the different steps in RNA extraction. Researchers at the NIH in the mid 1980’s set out to develop...with chloroform as in the above no-kit method. Researchers have also developed ways to “stabilize” RNA within...gene expression. There are several things that researchers can do to combat this issue. First and foremost...