We narrowed to 11 results for: KLF4
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TypeBlog Post...variation in the Klf4 isoform (KLF4s or KLF4L). Polycistronic cassettes that contained KLF4s had overall diminished...Gateway-Compatible Toolbox Podcast Segment The impact of KLF4 N-terminal variants on iPSC generation Deriving ...expression of transcription factors OCT3/4, SOX2, KLF4, and c-MYC is the established model for reprogramming... diminished KLF4 expression levels; this altered stoichiometry impacted reprogramming and global gene ... monocistronic expression of either variation of Klf4 did not lead to the observed reprogramming discrepancies...available at Addgene and include a variety of cMYC, KLF4, SOX2 and OCT4 DNA binding domain and transcription...patterns. Polycistronic cassettes that contained the KLF4L isoform had more robust initiation of reprogramming...
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pCXLE toolkit: Efficient episomal plasmid-based method to reprogram peripheral blood cells to iPSCs
TypeBlog Post...expression of the reprogramming factors- OCT3/4, SOX2, KLF4, and C-MYC [1]. For the derivation of clinical grade...vectors that encoded six factors - OCT3/4, SOX2, KLF4, C-MYC, LIN28 and SV40 large T antigen (SV40LT)....Plasmid Addgene ID# Encodes pCXLE-hSK 27078 SOX2 and KLF4 pCXLE-hUL 27080 L-MYC and LIN28 pCXLE-hOCT3/... -
Plasmids for Stem Cell Research
TypeCollection...expression of mouse Oct4, Sox2, Klf4, and c-Myc from polycistronic cassettes KLF4 N-terminal variance modulates... a cocktail of factors (Oct3/4, Sox2, c-Myc, and Klf4) that are known to maintain pluripotency during ...Lentivirus Human Expression of human Oct4, Sox2, Klf4, Myc, and Brd3R from five separate lentiviral plasmids...Doxycycline-inducible expression of human Oct4, Sox2, Klf4, and c-Myc from four separate lentiviral plasmids...vector for the expression of human Oct4, Sox2, and Klf4 Polycistronic lentiviral vector for "hit and run...lentiviral vector for the expression of human Oct4, Klf4, Sox2, and c-Myc Human Induced Pluripotent Stem ...lentiviral vector for the expression of human Oct4, Klf4, c-Myc, and Sox2 Integrative Analyses of Human Reprogramming... -
Hot Plasmids - September 2019 - CRISPR, Auxin Inducible Degradation, MerMAID Channelrhodopsins, and Genome Looping
TypeBlog Post.... When the group targeted the enhancer region of Klf4 and the promoter region of Zfp462, which are over... -
Four Factors that Differentiate the Stem Cell Field
TypeBlog Post...cells simply by expressing four proteins Oct4, Sox2, Klf4, and cMyc (the so called OSKM factors). As the Yamanaka... -
KLF Research Plasmids
TypeCollection...available plasmids, references, and links. KLF1 KLF2 KLF4 KLF5 KLF6 KLF Plasmids Browse Addgene's collection... -
Starter guide to induced pluripotent stem cells (iPSCs) part 1: A renaissance in regenerative medicine
TypeBlog Post... expression of four embryonic genes- OCT4, SOX2, KLF4, and C-MYC. iPSCs were first generated from mouse... -
Starter Guide to induced Pluripotent Stem Cells (iPSCs) Part 2: Reprogramming and Transdifferentiation
TypeBlog Post...overexpression of four reprogramming factors- OCT4, SOX2, KLF4, and C-MYC - that induce a differentiated somatic... -
Delivery Methods for Generating iPSCs
TypeBlog Post... reporters and RNAi) for: NANOG OCT4 SOX2 MYC KLF4 LIN28 Check out these plasmids if you’re interested... -
TALENs for Endogenous Zebrafish Genes
TypeCollection...TCGACTAGCACGCAGTAAattcaactacaatccgTTTGGGCTGCGATTCGGA klf4a TAL3478 & TAL3479 TGTCTCACCTGAAACGCCcctgcatgtctacaggTGCGACCTGCGCTGACCA... -
Immunology Research Plasmids and Resources
TypeCollection...chemokine-like factor C32, CKLF1, CKLF2, CKLF3, CKLF4, HSPC224, UCK-1 CMA1 chymase 1, mast cell CYH, MCT1...chemokine-like factor C32, CKLF1, CKLF2, CKLF3, CKLF4, HSPC224, UCK-1 CLCF1 cardiotrophin-like cytokine...