We narrowed to 8 results for: P300

...including pcDNA-dCas9-p300 Core and pcDNA3.3-Nm-dCas9-p300 Core, as well as pLV-dCas9-p300-P2A-PuroR for lentiviral...Transcriptional activation p300 acetyltransferase dCas9 fused to the catalytic domain of p300 acetyltransferase...lentiviral expression. Figure 1: dCas9-p300 adds H3K27ac marks to histones in promoter and enhancer...may work better than activators/repressors - dCas9-p300 increased transcriptional activation more than dCas9...

...especially exciting, including histone acetylation by p300, histone demethylation by LSD1, cytosine methylation...

...association with other members of the complex, such as p300 and CBP histone acetyltransferases or CARM1 methyltransferase...

...Tethering dCas9 to the histone acetyltransferase p300 or the DNA methyltransferase DNMT3A allows researchers...

... epigenetic modifiers. Common modifiers include: P300 — activation through increased H3K27 acetylation...

...5015):49-53. PubMed PMID: 1905840 . Recruitment of p300/CBP in p53-dependent signal pathways. Avantaggiati...

...demethylation. The most common modifiers include: P300 — activation through increased H3K27 acetylation...

...demethylation. The most common modifiers include: P300 — activation through increased H3K27 acetylation...