We narrowed to 11 results for: Tpr;
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TypeBlog Post...first-generation mARGs also had a large genetic footprint (two cassettes + a booster cassette), their expression...mARGs with higher expression, a smaller genetic footprint, and nonlinear acoustic scattering. The best candidate... Increasing expression and decreasing genetic footprint We took a cue from the native expression patterns...cassette, either, allowing us to reduce the genetic footprint yet again. This also led to improved expression...
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PiggyBac-ing Through the Genome Editing Field
TypeBlog Post...transposon gene modification system and the scarless, Footprint-Free™ removal of cargo with the excision-only ...thereby leaving behind only those cells with a Footprint-Free™ genome edit. Figure 2: Editing...nuclease to stimulate homologous recombination and Footprint-Free™ removal of the selection cassette by excision-only... -
Plasmids 101: Using Transposons in the Lab
TypeBlog Post...excises the transposon from the donor DNA. A DNA footprint is left behind. When the transposon-transposase...dinucleotides and it leaves behind the CAG DNA footprint from its terminal sequences at the excision site...other transposons, it does not leave behind a DNA footprint sequence after excision. piggyBac can mobilize... -
Delivery Methods for Generating iPSCs
TypeBlog Post.... Viral vectors also have the largest genomic footprint of iPSC generating methods due to the risk of ...Non-integrating methods have a smaller genetic footprint compared to integrating approaches. These methods... -
Simple CRISPR-based Epigenetic Editing: dCas9-directed DNA Demethylation
TypeBlog Post...Genome-wide tracking of dCas9-methyltransferase footprints. Nat Commun 9, 597. https://doi.org/10.1038/s41467... -
Hot Plasmids and Viral Preps - January 2021
TypeBlog Post...editing efficiency and reduced RNA-off target footprint compared to current N-terminal linked SaCas9 ABE... -
DNA Purification Without a Kit
TypeBlog Post...kits, but you’d like to reduce your lab’s waste footprint. The Zhao and Deng labs developed a simple method... -
Trimmer Lab NeuroMab Collection
TypeCollection...-Constant Mouse IgG2a 177504 Anti-LAR/PTPRF [N165/38R] LAR/PTPRF Human Mouse IgG2a 177505 Anti-PSD-93/...channel Rat Mouse IgG2a 188219 Anti-Pan-PTPR [N165/43R] Pan-PTPR Mouse IgG2a 188220 Anti-Kv2.1 K+ channel...Mouse IgG2b 225411 LAR/PTPRF (Homo sapiens) recombinant monoclonal antibody. LAR/PTPRF Human Mouse IgG2b 225412...MAP3K12 Mouse Mouse 219490 Anti-Pan-PTPR scFv [N165/43 scFv] N165/43 Pan-PTPR Human Mouse 219491 Anti-Rem2 scFv... -
Neurodegeneration Plasmid Collection
TypeCollection... British dementia Michael Ward 178161 ITPR1_Halo_N_allele ITPR1 Halo Spinocerebellar ataxia Michael Ward...19R] ITPR1 CMV Spinocerebellar ataxia James Trimmer 188177 Anti-IP3 receptor, type 1 [L24/1R] ITPR1 CMV.../1] ITPR1 CMV Spinocerebellar ataxia James Trimmer 206790 IP3 receptor, type 1 scFv [L24/21] ITPR1 CMV...Trimmer 188167 Anti-IP3 receptor, type 1 [L24/21R] ITPR1 CMV Spinocerebellar ataxia James Trimmer 188171 ...Trimmer 188185 Anti-IP3 receptor, type 1 [L24/11R] ITPR1 CMV Spinocerebellar ataxia James Trimmer 188393 ... -
CRISPR Plasmids - Tagging
TypeCollection...homozygous mutants with no co-integrated markers or footprints, and can be scaled up for systematic editing ... -
Immunology Research Plasmids and Resources
TypeCollection...HCPH, HPTP1C, PTP-1C, SH-PTP1, SHP-1, SHP-1L, SHP1 PTPRC protein tyrosine phosphatase, receptor type, C B220...