... WT YFP TARDBP YFP ALS Aaron Gitler 27695 GAK-pmCherryN1 GAK mCherry CMV Parkinson's Christien Merrifield...Spinocerebellar ataxia 18 Nicola Burgess-Brown 39042 GAK GAK TEV, His T7 Parkinson's Nicola Burgess-Brown 39529...Hallervorden-Spatz disease Cheryl Arrowsmith 79682 GAK_HUMAN_D0 GAK His, TEV Parkinson's John Chodera 79712 E2AK2...

...photoactivatable system to cleave a target DNA sequence (Nihongaki, et al., 2015) resulting in a double strand break...might expect from the modular nature of Cas9, Nihongaki et al. showed that it was possible to swap out... Split Systems / Light-induced Dimerization Nihongaki et al., 2015   CRY2 and CIB1 from A. thaliana ...thaliana dCas9 Activation of gene transcription Nihongaki et al., 2015 paCas9 Magnet proteins from N. crassa...HDR, repression of gene expression by CRISPRi Nihongaki et al., 2017 Split-CPTS2.0 CRY2 and CIB1 from ...6289 . https://doi.org/10.1002/anie.201900788 Nihongaki Y, Furuhata Y, Otabe T, Hasegawa S, Yoshimoto ...:963–966 . https://doi.org/10.1038/nmeth.4430 Nihongaki Y, Kawano F, Nakajima T, Sato M (2015) Photoactivatable...

...Addgene (Plasmid #83926). Live-Cell Voltage Sensor  Ingaki and colleagues (8) were interested in using photoactivatable...27786307. PubMed Central PMCID: PMC5476805. 8. Inagaki, S., et al. (2017) Genetically encoded bioluminescent...

... activates transcription of downstream genes. Nihongaki et al describe the targeted activation of endogenous...plasmids from this article through Addgene. Nihongaki et al., Chemistry and Biology. 2015 Feb 19; 22...

...Chen, Robert C. Robbins, Mark A. Kay, Michael T. Longaker, and Joseph C. Wu. "A nonviral minicircle vector...