p53 Pathway
Type
Collection
...Cyclin G1 or G2 CDC25 Cell division cycle 25C Cdk4/6 CDK4 CDK6 Cyclin-dependent kinase 4 or 6 CHK1 Checkpoint...p53 is the most frequently mutated gene (>50%) in human cancer; most of these mutations are missense mutations...mutagens like radiation or viruses (e.g., HPV, the human papillomavirus). These mutations interfere with .... Uncovering the role of p53 splice variants in human malignancy: a clinical perspective. Surget S, Khoury...45-53. PubMed PMID: 11780111 . p53 mutations in human cancers. Hollstein M, Sidransky D, Vogelstein B,...