We narrowed to 406 results for: LARGE

...degree of both specificity and sensitivity across a large number of loci and gRNA lengths. Recent alternatives...

...diversity of CRISPR systems, only time will tell how large the genome and transcriptome engineering toolbox...

...interact or oligomerize in cells? This question is largely unanswered. Ideally, fluorescent proteins should...

...themselves using computational approaches to analyze large data sets (myself included) and we are faced with...

...re happy to provide them, that never works on a large scale. The world is too big now. Mendenhall: So ...

... CRISPR Libraries Offer Genome-Wide Control for Large-Scale Functional Screens        ...

...for pan-mutation editing strategies by enabling large sequence integration without triggering immunotoxicity...therapies and CDK4/6 inhibitors, consistent with recent large-cohort studies linking APOBEC signatures to shorter...

...with the Cas9/sgRNAs vector (like PX330). For large changes (>100 bp insertions or deletions), we typically...lab typically use PAGE purified long oligos. For large changes (>100 bp insertions or deletions), the Zhang...

..., two full antibodies bound together may be too large. Using a complex that is one full antibody bound...and have lower binding affinity than some of the larger fragments.  Think of antibody fragments as new ...

...-assisted insertion tagging Kit; integration of large DNA fragments at user-defined locations NEB Cell-Imaging...

...many samples you may have, access to one or more large, expensive ultracentrifuge.  Figure 1: An ...

...in this educational video. “SLC6A8 belongs to a large family of solute channels that are responsible for...

...microscope showed us that, in monkey neurons, the large majority of the gold particles were in the cytoplasm...after it has been administered. Although we found a larger proportion on the membrane in mice neurons, most...

...communication has helped Addgene move from completing 2-3 large projects a year, on average, to completing 8-10 ...

...to be large enough to target larger areas, typically a few hundred nl. Alternatively, for larger brain...lentiviral vectors are superior packaging vectors for larger genes - they can hold up to 8 kb, while AAV can...

...) and even on 60 Minutes. We are blessed with a large community of scientists who support us by depositing...

...used in experiments. Retroviral vectors make up a large toolbox used by researchers for (among other things...

...germline editing. Although this paper represents a large step forward in the CRISPR field, it’s important...

... can be excited many times, thereby producing a large number of emitted photons before they are destroyed...

... lab management software aren’t just limited to large volume facilities; it can be useful in academic ...