We narrowed to 2,647 results for: LARGE

1. CHyMErA Large-Scale Exon Deletion hgRNA Library

   Pooled Library

   #209736

   Purpose

   CHyMErA Exon Deletion hgRNA Library allows identification of frame-preserving exons that affect cell fitness in human cells using the CHyMErA screening platform.

   Depositor

   Thomas Gonatopoulos-Pournatzis

   Article

   Xiao et al Mol Cell. 2024 Jul 11;84(13):2553-2572.e

   Expression

   Mammalian

   Use

   CRISPR and Lentiviral

   Available Since

   June 20, 2024

   Availability

   Academic Institutions and Nonprofits only

2. Large-scale mismatched sgRNA library for gene titration (human essential genes, CRISPRi)

   Pooled Library

   #136478

   Purpose

   Expresses gRNAs for gene titration of ~2400 human genes using CRISPRi

   Depositor

   Jonathan Weissman

   Article

   Jost et al Nat Biotechnol. 2020 Jan 13. pii: 10.103

   Expression

   Mammalian

   Species

   Homo sapiens

   Use

   CRISPR and Lentiviral

   Available Since

   Feb. 25, 2020

   Availability

   Academic Institutions and Nonprofits only

3. Ef1a_Large T-antigen_Ires_Puro

   Plasmid

   #18922

   Depositor

   Linzhao Cheng

   Article

   Mali et al Stem Cells. 2008 Aug . 26(8):1998-2005.

   Insert

   Large T Antigen (SV40gp6 Simian virus 40)
   

   Use

   Cre/Lox and Lentiviral

   Expression

   Mammalian

   Available Since

   Sept. 4, 2008

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

4. pSG5 Large T

   Plasmid

   #9053

   Depositor

   William Hahn

   Insert

   large T antigen (SV40gp6 simian virus)
   

   Expression

   Mammalian

   Available Since

   Jan. 5, 2006

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

5. pAWH-largeT

   Plasmid

   #133895

   Purpose

   Positive control when used in combination with pBWH-p53. Negative control when used in combination with pBWH-Lam. Expression of Gal4AD-largeT hybrid protein. Homology regions for recombination with pB

   Depositor

   Sebastian Maurer

   Article

   Yang et al Nat Commun. 2018 Sep 14;9(1):3747. doi:

   Insert

   LargeT
   

   Expression

   Yeast

   Promoter

   T7

   Available Since

   Dec. 20, 2019

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

6. pSG5 Large T K1

   Plasmid

   #9055

   Depositor

   William Hahn

   Insert

   large T antigen K1 (SV40gp6 simian virus)
   

   Expression

   Mammalian

   Mutation

   E107K. Mutation in pRb LxCxE binding domain.

   Available Since

   Dec. 7, 2005

   Availability

   Academic Institutions and Nonprofits only

7. LV_EF1a_SV40_Large_T_Antigen-P2A-Hygro_Barcode

   Plasmid

   #170255

   Purpose

   Barcoded lentiviral vector to express SV40 Large T Antigen in mammalian cells under control of EF1a promoter. Barcoded for transcript detection in single cell RNA-seq

   Depositor

   Prashant Mali

   Article

   Parekh et al iScience. 2021 Sep 20;24(10):103149. doi

   Insert

   SV40 Large T Antigen
   

   Use

   Lentiviral

   Promoter

   EF1a

   Available Since

   Sept. 23, 2021

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

8. pBabe-puro largeTcDNA

   Plasmid

   #14088

   Depositor

   William Hahn

   Article

   Zhao et al Cancer Cell. 2003 May . 3(5):483-95.

   Insert

   Large T antigen (SV40gp6 simian virus)
   

   Use

   Retroviral

   Expression

   Mammalian

   Available Since

   Feb. 22, 2007

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

9. pBABE-neo largeTcDNA

   Plasmid

   #1780

   Purpose

   Retroviral expression of Large T Antigen. Used to create immortalized cell lines.

   Depositor

   Bob Weinberg

   Article

   Hahn et al Mol Cell Biol 2002 Apr;22(7):2111-23.

   Insert

   large T antigen (SV40gp6 simian virus)
   

   Use

   Retroviral

   Expression

   Mammalian

   Available Since

   June 3, 2005

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

10. pBABE-zeo largeTcDNA

    Plasmid

    #1779

    Depositor

    Bob Weinberg

    Article

    Hahn et al Mol Cell Biol 2002 Apr;22(7):2111-23.

    Insert

    large T antigen (SV40gp6 simian virus)
    

    Use

    Retroviral

    Expression

    Mammalian

    Available Since

    July 18, 2006

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

11. pBABE-zeo largeTgenomic

    Plasmid

    #1778

    Depositor

    Bob Weinberg

    Article

    Hahn et al Mol Cell Biol 2002 Apr;22(7):2111-23.

    Insert

    large T and small T antigen (SV40gp6 simian virus)
    

    Use

    Retroviral

    Expression

    Mammalian

    Available Since

    June 23, 2005

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

12. pBABE-neo largeTgenomic

    Plasmid

    #10891

    Depositor

    William Hahn

    Insert

    large T and small T antigen (SV40gp6 simian virus)
    

    Use

    Retroviral

    Expression

    Mammalian

    Available Since

    Dec. 7, 2005

    Availability

    Academic Institutions and Nonprofits only

13. pBABE-neo largeTcDNA K1

    Plasmid

    #8581

    Depositor

    Bob Weinberg

    Article

    Hahn et al Mol Cell Biol 2002 Apr;22(7):2111-23.

    Insert

    large T antigen (SV40gp6 simian virus)
    

    Use

    Retroviral

    Expression

    Mammalian

    Mutation

    E107K. Alteration in pRB consensus binding motif…

    Available Since

    Sept. 26, 2005

    Availability

    Academic Institutions and Nonprofits only

14. PR_GEF (2XPDZ-mCherry-Larg (DH)

    Plasmid

    #80407

    Purpose

    Recruitable mCherry tagged RhoA GEF LARG (DH domain). Expresses in mammalian cells

    Depositor

    Michael Glotzer

    Article

    Wagner et al J Cell Biol. 2016 Jun 20;213(6):641-9. d

    Insert

    2XPDZ_mCherry_LARG DH (aa 766-997) (ARHGEF12 Human)
    

    Tags

    mCherry

    Expression

    Mammalian

    Mutation

    DH domain only (aa 766-997)

    Promoter

    CMV

    Available Since

    Aug. 15, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

15. LARG mCherry sspB in pcDNA3.1

    Plasmid

    #90459

    Purpose

    RhoA mediated cell migration

    Depositor

    Narasimhan Gautam

    Article

    O'Neill et al Dev Cell. 2018 Jun 15. pii: S1534-5807(1

    Inserts

    LARG DH-PH (aa 766–1138) (ARHGEF12 Human)
    mCherry
    sspB
    

    Expression

    Mammalian

    Mutation

    R73Q

    Promoter

    CMV

    Available Since

    June 28, 2018

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

16. LARG mtq sspB in pcDNA3.1

    Plasmid

    #90460

    Purpose

    RhoA mediated cell migration

    Depositor

    Narasimhan Gautam

    Article

    O'Neill et al Dev Cell. 2018 Jun 15. pii: S1534-5807(1

    Inserts

    LARG DH-PH (aa 766–1138) (ARHGEF12 Human)
    mTq
    sspB
    

    Expression

    Mammalian

    Mutation

    R73Q and deletion a.a. (234-239)

    Available Since

    June 28, 2018

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

17. pBABE-neo largeTcDNA H42Q

    Plasmid

    #9048

    Depositor

    Bob Weinberg

    Article

    Hahn et al Mol Cell Biol 2002 Apr;22(7):2111-23.

    Insert

    large T antigen (SV40gp6 simian virus)
    

    Use

    Retroviral

    Expression

    Mammalian

    Mutation

    H42Q. Renders J domain nonfunctional.

    Available Since

    Jan. 5, 2006

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

18. pLBCX-Large-T-antigenK1 mutant

    Plasmid

    #189978

    Purpose

    Retroviral vector used to immortalize human cells

    Depositor

    William Kaelin

    Article

    Shi et al Cancer Cell. 2022 Sep 12;40(9):939-956.e

    Insert

    Large-T-antigenK1 mutant
    

    Available Since

    Dec. 12, 2022

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

19. Lenti-UbC-LARGE1-EF1a-BSD

    Plasmid

    #205151

    Purpose

    Express UbC-driven LARGE1 and EF-1a driven BSD

    Depositor

    Monkol Lek

    Insert

    LARGE xylosyl- and glucuronyltransferase 1 (LARGE1 Human)
    

    Use

    Lentiviral

    Expression

    Mammalian

    Promoter

    UbC

    Available Since

    April 19, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

20. PR_GEF YFP (2XPDZ-YFP-LARG DH)

    Plasmid

    #80408

    Purpose

    Recruitable YFP tagged RhoA GEF LARG (DH domain). Expresses in mammalian cells

    Depositor

    Michael Glotzer

    Article

    Wagner et al J Cell Biol. 2016 Jun 20;213(6):641-9. d

    Insert

    2XPDZ_YFP_LARG DH (aa 766-997) (ARHGEF12 Human)
    

    Tags

    YFP

    Expression

    Mammalian

    Promoter

    CMV

    Available Since

    Aug. 15, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge