We narrowed to 427 results for: RAP

...one-size-fits-all approach to gene replacement therapy for most patients. But how does one go from “cut...possibilities at the bench and potentially in therapeutic applications. The potential of CRISPR has yet...

...various pieces were connected, as this enabled us to rapidly iterate and optimize our pipeline. After reviewing...plasmid sequences on a 96-well plate basis, but for rapid testing and refinements, we specified a select small...

...end_module_attribute %}{% module_attribute "wrap_field_tag" is_json="true" %}{% raw %}"div"{% endraw %...blog Plasmids 101: Gene, enhancer, and promoter trapping Plasmids 101: The Promoter Region – Let's Go!...

... developed, though, researchers at HuidaGene Therapeutics guessed that fusing MPG to an ABE would allow...recognize T and/or C substrates. The HuidaGene Therapeutics team has deposited their editors, called gTBE...

...analysis is complete, a new screen appears with a graphical representation of the results and a list of the... on the sample name or on its corresponding bar graph entry. Clicking to initiate the in-depth analysis...

...also known as the science videographer, is a retired botanist and oceanographer who has a blog and several...

...known functions has the potential to be used in therapeutics, as it can increase gene expression at certain..., Garnett MJ (2019) Prioritization of cancer therapeutic targets using CRISPR–Cas9 screens. Nature 568...

...from collaboration and the exchange of ideas. The rapid spread of optogenetics throughout the neuroscience...al. "Serotonergic versus nonserotonergic dorsal raphe projection neurons: differential participation in...

...Weaker. Commonly found in pBAD vectors. Good for rapid regulation and low basal expression; however, not...to scientists. Plasmids are oftentimes put to therapeutic uses, and in those cases it's important to identify...

... (SpyTag-GFP nanobody) assembled on beads. C) Micrograph of H1.8-GFP nucleosomes collected with MagIC-...of glutaraldehyde crosslinking: representative micrograph (C), particle orientation distribution and Fourier-shell...

...cell line. This design allows highly localized, rapid and reversible microtubule severing and has very... blue light to generate CRY2-CIB1 oligomers that trap the fusion protein away from its usual location,...

... genes with potentially harmful mutations in therapeutic settings. Silencing of a target gene is achieved...end_module_attribute %}{% module_attribute "wrap_field_tag" is_json="true" %}{% raw %}"div"{% endraw %...

...labeling it. The label can then be visualized by autoradiography and X-ray film for radioactively labeled probes...commonplace in laboratories. As scientific technologies rapidly progress, some common lab techniques we use now...

...universities are trying to compile more comprehensive demographic information about the postdoc work force, problems...sorted out there can be gaps in knowledge of demographics and the information is often confidential (see...

...endogenous protein activity and measure responses to therapeutics in real time. Let's take a closer look at several... on the cell surface. EGF treatment resulted in rapid internalization and diminished luminescence signal...

...mutations, the risk is high. You are generating a gene therapy product with CRISPR to (hopefully) be used in human...for mismatches within the gRNA sequence. Graphic courtesy of Maya Kostman. The most commonly...

...numerous applications, including transgenesis, gene-trap screens, and gene editing. How does the piggyBac...and M. H. Wilson, “piggyBac-ing models and new therapeutic strategies.,” Trends Biotechnol., vol. 33, no...

...and luckily genetics is a sector which has been rapidly growing. These factors left me optimistic that ...would advise you to be wary of companies which are rapidly expanding, as this might not be sustainable. After...

...real challenge. On top of that, in the midst of a rapidly changing, globalized environment re-emerging from...international mentors. Universities from five different geographical locations in Spain were enrolled: the University...

...directly manipulating affect an outcome (age, demographic, diet, etc., in a cancer drug clinical trial,...know type of distribution you are working with, graphing data with a histogram is sometimes sufficient ...