We narrowed to 749 results for: SOM

1. Expanding the Targeting Scope and Editing Efficiency of Adenine Base Editors

   Type

   Blog Post

   Published

   March 17, 2020, 1:32 p.m.

   ...before the Cas domain lets go of the DNA. ABEs are somewhat slow and need a strong Cas9 domain to “hold on...

2. Developing a cold tolerant E. coli using specialized chaperones

   Type

   Blog Post

   Published

   Jan. 28, 2020, 2:35 p.m.

   ...who not only survive, but thrive, in the face of some of Earth’s harshest environments: corrosive pH ranges...

3. Behind the scenes: Addgene’s new search engine and more

   Type

   Blog Post

   Published

   Dec. 12, 2019, 2:22 p.m.

   ...directly typing terms in a search bar, by ticking some boxes, by selecting a suggestion — how should these...

4. Opto-Nanobodies: Using Light to Manipulate Cell Signaling and Protein Purification

   Type

   Blog Post

   Published

   Nov. 19, 2019, 2:08 p.m.

   ...endogenous signaling activity in cells.  Let’s shed some light on the key components of OptoNBs, how they...

5. Q&A with Karen Katz and Carl Paratore, the Newest Members of the Addgene Board of Directors

   Type

   Blog Post

   Published

   Feb. 19, 2019, 1:36 p.m.

   ...scenarios. What is the best piece of career advice someone has given you? Katz: Pick up the phone. I think...

6. 7 Tips to Secure a STEAM Internship This Summer

   Type

   Blog Post

   Published

   Feb. 2, 2021, 2:15 p.m.

   ...programs tend to ask similar questions, thus devoting some time to writing a solid personal statement will ...

7. Clear and Accessible Writing

   Type

   Blog Post

   Published

   Feb. 15, 2024, 2:15 p.m.

   ... team, working together to share information. Sometimes it is most helpful to use a lot of jargon and ...

8. Back to Bacteria: CRISPR gRNA Multiplexing Using tRNAs

   Type

   Blog Post

   Published

   June 2, 2015, 6:06 p.m.

   ...described in this post in the graphic below - including some simple comparisons. The easy multiplexing afforded...

9. The time and cost required to make a plasmid

   Type

   Blog Post

   Published

   March 23, 2023, 1:15 p.m.

   ...What about all the reagents you need to order? Sometimes, it feels like an eternity of cloning, waiting...

10. Plasmid Tools for Microbiome Studies

    Type

    Blog Post

    Published

    June 27, 2019, 12:25 p.m.

    ...any RNA sequence. Downstream of the hairpin is a ribosome binding site (RBS) followed by a reporter gene...

11. Antibodies 101: Affinity Reagents

    Type

    Blog Post

    Published

    April 14, 2022, 1:15 p.m.

    ... clinical applications. Most of the time, when someone speaks about an affinity reagent, they’re talking...

12. What's New in CRISPR - November 2021

    Type

    Blog Post

    Published

    Nov. 18, 2021, 2:15 p.m.

    ... Angela Holmes Several labs have recently shared some exciting plasmid tools to optimize prime editing...

13. Announcing the Winners of the 2021 Michael Davidson and Roger Tsien Commemorative Conference Awards

    Type

    Blog Post

    Published

    Aug. 5, 2021, 12:15 p.m.

    ...fluorescent protein tools. This year, we’ve made some changes. In addition to supporting in-person conference...

14. Antibodies 101: Polyclonal Antibodies

    Type

    Blog Post

    Published

    July 14, 2021, 1:15 p.m.

    ... useful in experiments where the availability of some regions of the protein may be masked by crosslinking...

15. New Tool for Lineage Tracing: The ClonTracer Library

    Type

    Blog Post

    Published

    Sept. 22, 2015, 2:30 p.m.

    ...Novartis was actually really research oriented [and] somewhat similar to an academic research environment” with...

16. RaPID Detection of RNA-protein Interactions

    Type

    Blog Post

    Published

    Aug. 16, 2018, 12:40 p.m.

    ...Sometimes it feels like DNA and protein get all the attention.There are numerous ways to detect DNA-protein...

17. Plasmids 101: Cre-lox

    Type

    Blog Post

    Published

    Jan. 13, 2015, 3:47 p.m.

    ...cells or at specified times. Combining this with some of the loxP methods described above, a genetic modification...

18. Working with Nuclear Receptors

    Type

    Blog Post

    Published

    July 15, 2014, 4:03 p.m.

    ... Coregulators Coregulators constitute a group of some 400 molecules that have been shown to be required...

19. Quickest Way to Deposit Plasmids: The Deposit Spreadsheet

    Type

    Blog Post

    Published

    March 8, 2017, 3:15 p.m.

    ...spreadsheet (Figure 2) and are described in Table 1. Some cells have drop-down options for you to choose from...

20. Savvy Advocates Needed to Navigate a Scientific Enterprise in Flux

    Type

    Blog Post

    Published

    Sept. 13, 2016, 2:30 p.m.

    ...Workshop 2016 At past symposia, FoR worked to highlight some of the problems facing postdocs and graduate students...